PDB entry 6nvd

View 6nvd on RCSB PDB site
Description: crystal structure of mycobacterium tuberculosis dethiobiotin synthetase in complex with triazole linked compound 9
Deposited on 2019-02-05, released 2020-02-12
The last revision was dated 2020-02-12, with a file datestamp of 2020-02-07.
Experiment type: XRAY
Resolution: 2.44 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-232)
      • expression tag (6-7)
  • Chain 'B':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-End)
      • expression tag (6-7)
  • Chain 'C':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-End)
      • expression tag (6-7)
  • Chain 'D':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-End)
      • expression tag (6-7)
  • Heterogens: L4S, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6nvdA (A:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nvdA (A:)
ggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagv
tqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelae
pgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglva
asnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6nvdB (B:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nvdB (B:)
ggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagv
tqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelae
pgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglva
asnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6nvdC (C:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nvdC (C:)
ggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagv
tqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelae
pgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglva
asnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6nvdD (D:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nvdD (D:)
ggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagv
tqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelae
pgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglva
asnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv