PDB entry 6nvb

View 6nvb on RCSB PDB site
Description: Crystal structure of the inhibitor-free form of the serine protease kallikrein-4
Class: hydrolase
Keywords: protease, klk4, HYDROLASE
Deposited on 2019-02-04, released 2019-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-08-28, with a file datestamp of 2019-08-23.
Experiment type: XRAY
Resolution: 1.64 Å
R-factor: N/A
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kallikrein-4
    Species: Homo sapiens [TaxId:9606]
    Gene: KLK4, EMSP1, PRSS17, PSTS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y5K2 (0-End)
      • variant (165)
    Domains in SCOPe 2.08: d6nvba_
  • Chain 'B':
    Compound: Kallikrein-4
    Species: Homo sapiens [TaxId:9606]
    Gene: KLK4, EMSP1, PRSS17, PSTS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y5K2 (0-223)
      • variant (165)
    Domains in SCOPe 2.08: d6nvbb_
  • Chain 'C':
    Compound: Kallikrein-4
    Species: Homo sapiens [TaxId:9606]
    Gene: KLK4, EMSP1, PRSS17, PSTS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y5K2 (0-End)
      • variant (165)
    Domains in SCOPe 2.08: d6nvbc_
  • Chain 'D':
    Compound: Kallikrein-4
    Species: Homo sapiens [TaxId:9606]
    Gene: KLK4, EMSP1, PRSS17, PSTS
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9Y5K2 (0-223)
      • variant (165)
    Domains in SCOPe 2.08: d6nvbd_
  • Heterogens: GOL, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6nvbA (A:)
iingedcsphsqpwqaalvmenelfcsgvlvhpqwvlsaahcfqnsytiglglhsleadq
epgsqmveaslsvrhpeynrpllandlmlikldesvsesdtirsisiasqcptagnsclv
sgwgllangrmptvlqcvnvsvvseevcsklydplyhpsmfcagggqdqkdscngdsggp
licngylqglvsfgkapcgqvgvpgvytnlckftewiektvqas

    Sequence, based on observed residues (ATOM records): (download) 
    >6nvbA (A:)
iingedcsphsqpwqaalvmenelfcsgvlvhpqwvlsaahcfqnsytiglglhsleadq
epgsqmveaslsvrhpeynrpllandlmlikldesvsesdtirsisiasqcptagnsclv
sgwgllangrmptvlqcvnvsvvseevcsklydplyhpsmfcagggqdqkdscngdsggp
licngylqglvsfgkapcgqvgvpgvytnlckftewiektvqa

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6nvbB (B:)
iingedcsphsqpwqaalvmenelfcsgvlvhpqwvlsaahcfqnsytiglglhsleadq
epgsqmveaslsvrhpeynrpllandlmlikldesvsesdtirsisiasqcptagnsclv
sgwgllangrmptvlqcvnvsvvseevcsklydplyhpsmfcagggqdqkdscngdsggp
licngylqglvsfgkapcgqvgvpgvytnlckftewiektvqas

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6nvbC (C:)
iingedcsphsqpwqaalvmenelfcsgvlvhpqwvlsaahcfqnsytiglglhsleadq
epgsqmveaslsvrhpeynrpllandlmlikldesvsesdtirsisiasqcptagnsclv
sgwgllangrmptvlqcvnvsvvseevcsklydplyhpsmfcagggqdqkdscngdsggp
licngylqglvsfgkapcgqvgvpgvytnlckftewiektvqas

    Sequence, based on observed residues (ATOM records): (download) 
    >6nvbC (C:)
iingedcsphsqpwqaalvmenelfcsgvlvhpqwvlsaahcfqnsytiglglhsleadq
epgsqmveaslsvrhpeynrpllandlmlikldesvsesdtirsisiasqcptagnsclv
sgwgllangrmptvlqcvnvsvvseevcsklydplyhpsmfcagggqdqkdscngdsggp
licngylqglvsfgkapcgqvgvpgvytnlckftewiektvqa

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6nvbD (D:)
iingedcsphsqpwqaalvmenelfcsgvlvhpqwvlsaahcfqnsytiglglhsleadq
epgsqmveaslsvrhpeynrpllandlmlikldesvsesdtirsisiasqcptagnsclv
sgwgllangrmptvlqcvnvsvvseevcsklydplyhpsmfcagggqdqkdscngdsggp
licngylqglvsfgkapcgqvgvpgvytnlckftewiektvqas