PDB entry 6nu6

View 6nu6 on RCSB PDB site
Description: crystal structure of mycobacterium tuberculosis dethiobiotin synthetase in complex with fragment analogue 5
Deposited on 2019-01-31, released 2020-02-05
The last revision was dated 2020-02-05, with a file datestamp of 2020-01-31.
Experiment type: XRAY
Resolution: 2.44 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-232)
      • expression tag (6-7)
  • Chain 'B':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-End)
      • expression tag (6-7)
  • Chain 'C':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-232)
      • expression tag (5-7)
  • Chain 'D':
    Compound: ATP-dependent dethiobiotin synthetase BioD
    Species: Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [TaxId:83332]
    Gene: bioD, Rv1570, MTCY336.33c
    Database cross-references and differences (RAF-indexed):
    • Uniprot P9WPQ5 (8-End)
      • expression tag (5-7)
  • Heterogens: L1V, L1Y, SO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6nu6A (A:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nu6A (A:)
ggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagv
tqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelae
pgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglva
asnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6nu6B (B:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nu6B (B:)
ggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlagv
tqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvelae
pgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglva
asnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6nu6C (C:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nu6C (C:)
hggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlag
vtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvela
epgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglv
aasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6nu6D (D:)
hhhhhhggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaev
grlagvtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggl
lvelaepgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpd
ppglvaasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglvg

    Sequence, based on observed residues (ATOM records):
    >6nu6D (D:)
hggtilvvtgtgtgvgktvvcaalasaarqagidvavckpvqtgtargdddlaevgrlag
vtqlaglarypqpmapaaaaehagmalpardqivrliadldrpgrltlvegaggllvela
epgvtlrdvavdvaaaalvvvtadlgtlnhtkltlealaaqqvscaglvigswpdppglv
aasnrsalariamvraalpagaasldagdfaamsaaafdrnwvaglv