PDB entry 6nq3

View 6nq3 on RCSB PDB site
Description: crystal structure of a suz12-rbbp4-phf19-jarid2 heterotetrameric complex
Deposited on 2019-01-19, released 2020-01-29
The last revision was dated 2020-04-08, with a file datestamp of 2020-04-03.
Experiment type: XRAY
Resolution: 2.89 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-binding protein RBBP4
    Species: Homo sapiens [TaxId:9606]
    Gene: RBBP4, RBAP48
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Polycomb protein SUZ12
    Species: Homo sapiens [TaxId:9606]
    Gene: SUZ12, CHET9, JJAZ1, KIAA0160
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: PHD finger protein 19
    Species: Homo sapiens [TaxId:9606]
    Gene: PHF19, PCL3
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Protein Jumonji
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Histone-binding protein RBBP4
    Species: Homo sapiens [TaxId:9606]
    Gene: RBBP4, RBAP48
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Polycomb protein SUZ12
    Species: Homo sapiens [TaxId:9606]
    Gene: SUZ12, CHET9, JJAZ1, KIAA0160
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: PHD finger protein 19
    Species: Homo sapiens [TaxId:9606]
    Gene: PHF19, PCL3
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Protein Jumonji
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6nq3A (A:)
mshhhhhhlvprgsmadkeaafddaveervineeykiwkkntpflydlvmthalewpslt
aqwlpdvtrpegkdfsihrlvlgthtsdeqnhlviasvqlpnddaqfdashydsekgefg
gfgsvsgkieieikinhegevnrarympqnpciiatktpssdvlvfdytkhpskpdpsge
cnpdlrlrghqkegyglswnpnlsghllsasddhticlwdisavpkegkvvdaktiftgh
tavvedvswhllheslfgsvaddqklmiwdtrsnntskpshsvdahtaevnclsfnpyse
filatgsadktvalwdlrnlklklhsfeshkdeifqvqwsphnetilassgtdrrlnvwd
lskigeeqspedaedgppellfihgghtakisdfswnpnepwvicsvsednimqvwqmae
niyndedpegsvdpegqgs

    Sequence, based on observed residues (ATOM records):
    >6nq3A (A:)
afddaveervineeykiwkkntpflydlvmthalewpsltaqwlpdvtrpegkdfsihrl
vlgthtsdeqnhlviasvqlpnddgkieieikinhegevnrarympqnpciiatktpssd
vlvfdytkhpskpdpsgecnpdlrlrghqkegyglswnpnlsghllsasddhticlwdis
avpkvvdaktiftghtavvedvswhllheslfgsvaddqklmiwdtrsnntskpshsvda
htaevnclsfnpysefilatgsadktvalwdlrnlklklhsfeshkdeifqvqwsphnet
ilassgtdrrlnvwdlskigeeqspedaedgppellfihgghtakisdfswnpnepwvic
svsednimqvwqmaeniynde

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6nq3B (B:)
mehvqadhelflqafekptqiyrflrtrnliapiflhrtltymshrnsrtnikrktfkvd
dmlskvekmkgeqeshslsahlqltftgffhkndkpspnseneqnsvtlevllvkvchkk
rkdvscpirqvptgkkqvplnpdlnqtkpgnfpslavssnefepsnshmvksysllfrvt
rpgrrefngmingetnenidvneelparrkrnredgektfvaqmtvfdknrrlqlldgey
evamqemeecpiskkratwetildgkrlppfetfsqgptlqftlrwtgetndkstapiak
platrnseslhqenkpgsvkptqtiavkeslttdlqtrkekdtpnenrqklrifyqflyn
nntrqqtearddlhcpwctlncrklysllkhlklchsrfifnyvyhpkgaridvsinecy
dgsyagnpqdihrqpgfafsrngpvkrtpithilvcrpkrtkasmseflewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6nq3B (B:)
vqadhelflqafekptqiyrflrtrnliapiflhrtltymshrnsrtnikrktfkvddml
skvekmkhlqltftgffhvtlevllvkvchkkrkdvscpirqvptpslavssnefepsns
hmvksysllfrvfvaqmtvfdknrrlqlldgeyevamqekkratwetiqgptlqftlrks
tapiakplaqklrifyqflynnntrqqtearddlhcpwctlncrklysllkhlklchsrf
ifnyvyhpkgaridvsinecyddihrqpgfafsrngpvkrtpithilvcrp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6nq3C (C:)
snasdssaegasvperpdegidshtfesiseddsslshlkssitnyfgaagrlacgekyq
vlarrvtpegkvqylvewegttpy

    Sequence, based on observed residues (ATOM records):
    >6nq3C (C:)
ddsslshlkssitnyfgaagrlacgekyqvlarrvtpegkvqylvewegttpy

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6nq3D (D:)
lskrkpktedfltflclrg

    Sequence, based on observed residues (ATOM records):
    >6nq3D (D:)
krkpktedfltflclrg

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6nq3E (E:)
mshhhhhhlvprgsmadkeaafddaveervineeykiwkkntpflydlvmthalewpslt
aqwlpdvtrpegkdfsihrlvlgthtsdeqnhlviasvqlpnddaqfdashydsekgefg
gfgsvsgkieieikinhegevnrarympqnpciiatktpssdvlvfdytkhpskpdpsge
cnpdlrlrghqkegyglswnpnlsghllsasddhticlwdisavpkegkvvdaktiftgh
tavvedvswhllheslfgsvaddqklmiwdtrsnntskpshsvdahtaevnclsfnpyse
filatgsadktvalwdlrnlklklhsfeshkdeifqvqwsphnetilassgtdrrlnvwd
lskigeeqspedaedgppellfihgghtakisdfswnpnepwvicsvsednimqvwqmae
niyndedpegsvdpegqgs

    Sequence, based on observed residues (ATOM records):
    >6nq3E (E:)
afddaveervineeykiwkkntpflydlvmthalewpsltaqwlpdvtrpegkdfsihrl
vlgthtsdeqnhlviasvqlpnddsgkieieikinhegevnrarympqnpciiatktpss
dvlvfdytkhpskpdpsgecnpdlrlrghqkegyglswnpnlsghllsasddhticlwdi
savpgkvvdaktiftghtavvedvswhllheslfgsvaddqklmiwdtrsnntskpshsv
dahtaevnclsfnpysefilatgsadktvalwdlrnlklklhsfeshkdeifqvqwsphn
etilassgtdrrlnvwdlskigeeqspedaedgppellfihgghtakisdfswnpnepwv
icsvsednimqvwqmaeniynd

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6nq3F (F:)
mehvqadhelflqafekptqiyrflrtrnliapiflhrtltymshrnsrtnikrktfkvd
dmlskvekmkgeqeshslsahlqltftgffhkndkpspnseneqnsvtlevllvkvchkk
rkdvscpirqvptgkkqvplnpdlnqtkpgnfpslavssnefepsnshmvksysllfrvt
rpgrrefngmingetnenidvneelparrkrnredgektfvaqmtvfdknrrlqlldgey
evamqemeecpiskkratwetildgkrlppfetfsqgptlqftlrwtgetndkstapiak
platrnseslhqenkpgsvkptqtiavkeslttdlqtrkekdtpnenrqklrifyqflyn
nntrqqtearddlhcpwctlncrklysllkhlklchsrfifnyvyhpkgaridvsinecy
dgsyagnpqdihrqpgfafsrngpvkrtpithilvcrpkrtkasmseflewshpqfek

    Sequence, based on observed residues (ATOM records):
    >6nq3F (F:)
adhelflqafekptqiyrflrtrnliapiflhrtltymshrnsrtnikrktfkvddmlsk
vekmkgehlqltftgffevllvkvchkkrkdvscpirqvlavssnefepsnshmvksysl
lfrvfvaqmtvfdknrrlqlldgeyevamqekkratweptlqftlkstapiakplaqklr
ifyqflynnntrqqtearddlhcpwctlncrklysllkhlklchsrfifnyvyhpkgari
dvsinecyddihrqpgfafsrngpvkrtpithilvcrp

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6nq3G (G:)
snasdssaegasvperpdegidshtfesiseddsslshlkssitnyfgaagrlacgekyq
vlarrvtpegkvqylvewegttpy

    Sequence, based on observed residues (ATOM records):
    >6nq3G (G:)
sslshlkssitnyfgaagrlacgekyqvlarrvtpegkvqylvewegttpy

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6nq3H (H:)
lskrkpktedfltflclrg

    Sequence, based on observed residues (ATOM records):
    >6nq3H (H:)
krkpktedfltflclrg