PDB entry 6np9
View 6np9 on RCSB PDB site
Description: PD-L1 IgV domain V76T with fragment
Class: immune system
Keywords: Fragment-based screening, Structure-based design, PD-L1 inhibitor, Cancer drug discovery, Immunotherapy, IMMUNE SYSTEM
Deposited on
2019-01-17, released
2019-02-20
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-11-27, with a file datestamp of
2019-11-22.
Experiment type: XRAY
Resolution: 1.27 Å
R-factor: N/A
AEROSPACI score: 0.6
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Programmed cell death 1 ligand 1
Species: Homo sapiens [TaxId:9606]
Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
Database cross-references and differences (RAF-indexed):
- Uniprot Q9NZQ7 (0-116)
- engineered mutation (58)
- expression tag (117-123)
Domains in SCOPe 2.08: d6np9a1, d6np9a2 - Heterogens: SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6np9A (A:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlktq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lhehhhh
Sequence, based on observed residues (ATOM records): (download)
>6np9A (A:)
aftvtvpkdlyvveygsnmtieckfpvqldlaalivywemedkniiqfvhgeedlktqhs
syrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaalh
eh