PDB entry 6nnv

View 6nnv on RCSB PDB site
Description: pd-l1 igv domain complex with macro-cyclic peptide
Deposited on 2019-01-15, released 2019-02-20
The last revision was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 1.92 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • engineered mutation (58)
      • expression tag (117-118)
  • Chain 'B':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • engineered mutation (58)
      • expression tag (117-122)
  • Chain 'C':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • engineered mutation (58)
      • expression tag (117-124)
  • Chain 'D':
    Compound: Programmed cell death 1 ligand 1
    Species: Homo sapiens [TaxId:9606]
    Gene: CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9NZQ7 (0-116)
      • engineered mutation (58)
      • expression tag (117-122)
  • Chain 'I':
    Compound: macrocyclic peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6NNV
  • Chain 'J':
    Compound: macrocyclic peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6NNV
  • Chain 'K':
    Compound: macrocyclic peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6NNV
  • Chain 'L':
    Compound: macrocyclic peptide
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6NNV
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6nnvA (A:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlktq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lhehhhh

    Sequence, based on observed residues (ATOM records):
    >6nnvA (A:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlktq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaa

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6nnvB (B:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlktq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lhehhhh

    Sequence, based on observed residues (ATOM records):
    >6nnvB (B:)
aftvtvpkdlyvveygsnmtieckfpveldlaalivywemedkniiqfvhgeedlktqhs
syrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaalh
e

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6nnvC (C:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlktq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lhehhhh

    Sequence, based on observed residues (ATOM records):
    >6nnvC (C:)
aftvtvpkdlyvveygsnmtieckfpveldlaalivywemedkniiqfvhgeedlktqhs
syrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaalh
ehh

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6nnvD (D:)
aftvtvpkdlyvveygsnmtieckfpvekqldlaalivywemedkniiqfvhgeedlktq
hssyrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaa
lhehhhh

    Sequence, based on observed residues (ATOM records):
    >6nnvD (D:)
aftvtvpkdlyvveygsnmtieckfpveldlaalivywemedkniiqfvhgeedlktqhs
syrqrarllkdqlslgnaalqitdvklqdagvyrcmisyggadykritvkvnapyaaalh
e

  • Chain 'I':
    Sequence; same for both SEQRES and ATOM records:
    >6nnvI (I:)
ffxgdvfygwylck

  • Chain 'J':
    Sequence; same for both SEQRES and ATOM records:
    >6nnvJ (J:)
ffxgdvfygwylck

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records:
    >6nnvK (K:)
ffxgdvfygwylck

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records:
    >6nnvL (L:)
ffxgdvfygwylck