PDB entry 6nmq

View 6nmq on RCSB PDB site
Description: Hypoxia-Inducible Factor (HIF) Prolyl Hydroxylase 2 (PHD2) in Complex with the Carboxamide Analog JNJ43058171
Class: oxidoreductase
Keywords: PHD2, hypoxia-inducible factor prolyl hydroxylase, iron-containing enzyme, cinnoline, OXIDOREDUCTASE
Deposited on 2019-01-11, released 2019-04-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-26, with a file datestamp of 2019-06-21.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Egl nine homolog 1
    Species: Homo sapiens [TaxId:9606]
    Gene: EGLN1, C1orf12, PNAS-118, PNAS-137
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6nmqa_
  • Heterogens: FE2, KU1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6nmqA (A:)
rpngqtkplpalklaleyivpcmnkhgicvvddflgketgqqigdevralhdtgkftdgq
lvsqksdsskdirgdkitwiegkepgcetigllmssmddlirhcngklgsykingrtkam
vacypgngtgyvrhvdnpngdgrcvtciyylnkdwdakvsggilrifpegkaqfadiepk
fdrllffwsdrrnphevqpayatryaitvwyfd

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmqA (A:)
palklaleyivpcmnkhgicvvddflgketgqqigdevralhdtgkftdkitwiegkepg
cetigllmssmddlirhcngklgsykingrtkamvacypgngtgyvrhvdnpngdgrcvt
ciyylnkdwdakvsggilrifpegkaqfadiepkfdrllffwsdrrnphevqpayatrya
itvwyfd