PDB entry 6nmm

View 6nmm on RCSB PDB site
Description: Ternary complex structure of the T130K mutant of ANT-4 with Neomycin, AMPCPP and Pyrophosphate
Class: transferase/ANTIBIOTIC
Keywords: Aminoglycoside nucelotidyl transferase (ANT) Aminoglycoside modifying enzymes (AGMEs) DNA polymerase, ANTIBIOTIC, transferase-ANTIBIOTIC complex
Deposited on 2019-01-11, released 2020-01-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-06, with a file datestamp of 2020-05-01.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: kanamycin nucleotidyltransferase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57514 (Start-255)
      • conflict (82)
    Domains in SCOPe 2.08: d6nmma1, d6nmma2
  • Chain 'B':
    Compound: kanamycin nucleotidyltransferase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57514 (Start-255)
      • conflict (82)
    Domains in SCOPe 2.08: d6nmmb1, d6nmmb2
  • Chain 'C':
    Compound: kanamycin nucleotidyltransferase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57514 (Start-255)
      • conflict (82)
    Domains in SCOPe 2.08: d6nmmc1, d6nmmc2
  • Chain 'D':
    Compound: kanamycin nucleotidyltransferase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57514 (Start-255)
      • conflict (82)
    Domains in SCOPe 2.08: d6nmmd1, d6nmmd2
  • Heterogens: NMY, A, PPV, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6nmmA (A:)
gshmngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvm
steeaefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggyle
kvyqtaksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamli
glhhricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqew
terhgyivdvskripf

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmmA (A:)
ngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvmstee
aefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggylekvyq
taksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamliglhh
ricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqewterh
gyivdvskripf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6nmmB (B:)
gshmngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvm
steeaefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggyle
kvyqtaksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamli
glhhricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqew
terhgyivdvskripf

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmmB (B:)
ngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvmstee
aefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggylekvyq
taksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamliglhh
ricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqewterh
gyivdvskripf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6nmmC (C:)
gshmngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvm
steeaefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggyle
kvyqtaksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamli
glhhricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqew
terhgyivdvskripf

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmmC (C:)
ngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvmstee
aefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggylekvyq
taksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamliglhh
ricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqewterh
gyivdvskripf

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6nmmD (D:)
gshmngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvm
steeaefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggyle
kvyqtaksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamli
glhhricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqew
terhgyivdvskripf

    Sequence, based on observed residues (ATOM records): (download) 
    >6nmmD (D:)
ngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvmstee
aefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggylekvyq
taksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamliglhh
ricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqewterh
gyivdvskripf