PDB entry 6nml

View 6nml on RCSB PDB site
Description: Ternary structure of the T130K mutant of ANT-4'' with Neomycin and AMPCPP
Class: transferase/ANTIBIOTIC
Keywords: Aminoglycoside nucelotidyl transferase (ANT) Aminoglycoside modifying enzymes (AGMEs) DNA polymerase, ANTIBIOTIC, transferase-ANTIBIOTIC complex
Deposited on 2019-01-11, released 2020-01-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-05-06, with a file datestamp of 2020-05-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: kanamycin nucleotidyltransferase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57514 (3-255)
      • conflict (82)
    Domains in SCOPe 2.08: d6nmla1, d6nmla2
  • Chain 'B':
    Compound: kanamycin nucleotidyltransferase
    Species: Geobacillus stearothermophilus [TaxId:1422]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q57514 (Start-255)
      • conflict (82)
    Domains in SCOPe 2.08: d6nmlb1, d6nmlb2
  • Heterogens: NMY, APC, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6nmlA (A:)
    gshmngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvm
    steeaefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggyle
    kvyqtaksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamli
    glhhricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqew
    terhgyivdvskripf
    

    Sequence, based on observed residues (ATOM records): (download)
    >6nmlA (A:)
    mngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvmste
    eaefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggylekvy
    qtaksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamliglh
    hricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqewter
    hgyivdvskripf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6nmlB (B:)
    gshmngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvm
    steeaefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggyle
    kvyqtaksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamli
    glhhricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqew
    terhgyivdvskripf
    

    Sequence, based on observed residues (ATOM records): (download)
    >6nmlB (B:)
    ngpiimtreermkivheikerildkygddvkaigvygslgrqtdgpysdiemmcvmstee
    aefshewttgewkvevnfdseeilldyasqvesdwplthgqffsilpiydsggylekvyq
    taksveaqkfhdaicaliveelfeyagkwrnirvqgpttflpsltvqvamagamliglhh
    ricyttsasvlteavkqsdlpsgydhlcqfvmsgqlsdseklleslenfwngiqewterh
    gyivdvskripf