PDB entry 6nj5

View 6nj5 on RCSB PDB site
Description: Thermostable variant of human carbonic anhydrase II with disordered tetrazine 2.0 at site 233
Class: lyase
Keywords: genetic code expansion, thermostability, protein engineering, LYASE
Deposited on 2019-01-02, released 2019-10-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-28, with a file datestamp of 2020-10-23.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.7 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: CA2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00918 (2-259)
      • expression tag (1)
      • engineered mutation (64)
      • engineered mutation (99)
      • engineered mutation (152)
      • engineered mutation (222)
      • engineered mutation (232)
      • engineered mutation (238)
      • engineered mutation (246)
      • expression tag (260-265)
    Domains in SCOPe 2.08: d6nj5a1, d6nj5a2, d6nj5a3
  • Heterogens: ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6nj5A (A:)
mahhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslril
nnghtfnvefddsqdkavlkggpldgtyrliqfhfhwgshdgqgsehtvdkkkyaaelhl
vhwntkygdfgkavqqpdglavlgiflkvgsanpglqkvvdvldsiktkgksadftnfdp
rgllpesldywtypgslttppllecvtwivlkepisvsseqvskfrklnfngxgepeepm
vdnwrptqplknrqikasfkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6nj5A (A:)
ahhwgygkhngpehwhkdfpiakgerqspvdidthtakydpslkplsvsydqatslriln
nghtfnvefddsqdkavlkggpldgtyrliqfhfhwgshdgqgsehtvdkkkyaaelhlv
hwntkygdfgkavqqpdglavlgiflkvgsanpglqkvvdvldsiktkgksadftnfdpr
gllpesldywtypgslttppllecvtwivlkepisvsseqvskfrklnfngxgepeepmv
dnwrptqplknrqikasfkhhhhhh