PDB entry 6nig

View 6nig on RCSB PDB site
Description: crystal structure of the human tlr2-diprovocim complex
Deposited on 2018-12-27, released 2019-04-17
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Toll-like receptor 2,Variable lymphocyte receptor B
    Species: Eptatretus stoutii [TaxId:7765]
    Gene: VLRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60603 (Start-506)
      • linker (507)
    • Uniprot Q2YE02 (508-End)
  • Chain 'B':
    Compound: Toll-like receptor 2,Variable lymphocyte receptor B
    Species: Eptatretus stoutii [TaxId:7765]
    Gene: VLRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60603 (Start-506)
      • linker (507)
    • Uniprot Q2YE02 (508-End)
  • Chain 'C':
    Compound: Toll-like receptor 2,Variable lymphocyte receptor B
    Species: Eptatretus stoutii [TaxId:7765]
    Gene: VLRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60603 (Start-506)
      • linker (507)
    • Uniprot Q2YE02 (508-End)
  • Chain 'D':
    Compound: Toll-like receptor 2,Variable lymphocyte receptor B
    Species: Eptatretus stoutii [TaxId:7765]
    Gene: VLRB
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60603 (Start-506)
      • linker (507)
    • Uniprot Q2YE02 (508-End)
  • Heterogens: KQD, NAG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6nigA (A:)
mphtlwmvwvlgviislskeessnqaslscdrngickgssgslnsipsglteavksldls
nnrityisnsdlqrcvnlqalvltsngintieedsfsslgslehldlsynylsnlssswf
kplssltflnllgnpyktlgetslfshltklqilrvgnmdtftkiqrkdfagltfleele
idasdlqsyepkslksiqnvshlilhmkqhillleifvdvtssveclelrdtdldtfhfs
elstgetnslikkftfrnvkitdeslfqvmkllnqisgllelefddctlngvgnfrasdn
drvidpgkvetltirrlhiprfylfydlstlysltervkritvenskvflvpcllsqhlk
sleyldlsenlmveeylknsacedawpslqtlilrqnhlaslektgetlltlknltnidi
sknsfhsmpetcqwpekmkylnlsstrihsvtgcipktleildvsnnnlnlfslnlpqlk
elyisrnklmtlpdasllpmllvlkisrnqlksvpdgifdrltslqkiwlhtnpwdcscp
ridylsrwlnknsqkeqgsakcsgsgkpvrsiicpt

    Sequence, based on observed residues (ATOM records):
    >6nigA (A:)
slscdrngickgssgslnsipsglteavksldlsnnrityisnsdlqrcvnlqalvltsn
gintieedsfsslgslehldlsynylsnlssswfkplssltflnllgnpyktlgetslfs
hltklqilrvgnmdtftkiqrkdfagltfleeleidasdlqsyepkslksiqnvshlilh
mkqhillleifvdvtssveclelrdtdldtfhfselstnslikkftfrnvkitdeslfqv
mkllnqisgllelefddctlngvgnfrasdndrvidpgkvetltirrlhiprfylfydls
tlysltervkritvenskvflvpcllsqhlksleyldlsenlmveeylknsacedawpsl
qtlilrqnhlaslektgetlltlknltnidisknsfhsmpetcqwpekmkylnlsstrih
svtgcipktleildvsnnnlnlfslnlpqlkelyisrnklmtlpdasllpmllvlkisrn
qlksvpdgifdrltslqkiwlhtnpwdcscpridylsrwlnknsqkeqgsakcsgsgkpv
rsiicp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6nigB (B:)
mphtlwmvwvlgviislskeessnqaslscdrngickgssgslnsipsglteavksldls
nnrityisnsdlqrcvnlqalvltsngintieedsfsslgslehldlsynylsnlssswf
kplssltflnllgnpyktlgetslfshltklqilrvgnmdtftkiqrkdfagltfleele
idasdlqsyepkslksiqnvshlilhmkqhillleifvdvtssveclelrdtdldtfhfs
elstgetnslikkftfrnvkitdeslfqvmkllnqisgllelefddctlngvgnfrasdn
drvidpgkvetltirrlhiprfylfydlstlysltervkritvenskvflvpcllsqhlk
sleyldlsenlmveeylknsacedawpslqtlilrqnhlaslektgetlltlknltnidi
sknsfhsmpetcqwpekmkylnlsstrihsvtgcipktleildvsnnnlnlfslnlpqlk
elyisrnklmtlpdasllpmllvlkisrnqlksvpdgifdrltslqkiwlhtnpwdcscp
ridylsrwlnknsqkeqgsakcsgsgkpvrsiicpt

    Sequence, based on observed residues (ATOM records):
    >6nigB (B:)
slscdrngickgssgslnsipsglteavksldlsnnrityisnsdlqrcvnlqalvltsn
gintieedsfsslgslehldlsynylsnlssswfkplssltflnllgnpyktlgetslfs
hltklqilrvgnmdtftkiqrkdfagltfleeleidasdlqsyepkslksiqnvshlilh
mkqhillleifvdvtssveclelrdtdldtfhfselstgetnslikkftfrnvkitdesl
fqvmkllnqisgllelefddctlngvgnfrasdidpgkvetltirrlhiprfylfydlst
lysltervkritvenskvflvpcllsqhlksleyldlsenlmveeylknsacedawpslq
tlilrqnhlaslektgetlltlknltnidisknsfhsmpetcqwpekmkylnlsstrihs
vtgcipktleildvsnnnlnlfslnlpqlkelyisrnklmtlpdasllpmllvlkisrnq
lksvpdgifdrltslqkiwlhtnpwdcscpridylsrwlnknsqkeqgsakcsgsgkpvr
siicp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6nigC (C:)
mphtlwmvwvlgviislskeessnqaslscdrngickgssgslnsipsglteavksldls
nnrityisnsdlqrcvnlqalvltsngintieedsfsslgslehldlsynylsnlssswf
kplssltflnllgnpyktlgetslfshltklqilrvgnmdtftkiqrkdfagltfleele
idasdlqsyepkslksiqnvshlilhmkqhillleifvdvtssveclelrdtdldtfhfs
elstgetnslikkftfrnvkitdeslfqvmkllnqisgllelefddctlngvgnfrasdn
drvidpgkvetltirrlhiprfylfydlstlysltervkritvenskvflvpcllsqhlk
sleyldlsenlmveeylknsacedawpslqtlilrqnhlaslektgetlltlknltnidi
sknsfhsmpetcqwpekmkylnlsstrihsvtgcipktleildvsnnnlnlfslnlpqlk
elyisrnklmtlpdasllpmllvlkisrnqlksvpdgifdrltslqkiwlhtnpwdcscp
ridylsrwlnknsqkeqgsakcsgsgkpvrsiicpt

    Sequence, based on observed residues (ATOM records):
    >6nigC (C:)
slscdrngickgssgslnsipsglteavksldlsnnrityisnsdlqrcvnlqalvltsn
gintieedsfsslgslehldlsynylsnlssswfkplssltflnllgnpyktlgetslfs
hltklqilrvgnmdtftkiqrkdfagltfleeleidasdlqsyepkslksiqnvshlilh
mkqhillleifvdvtssveclelrdtdldtfhfselstgetnslikkftfrnvkitdesl
fqvmkllnqisgllelefddctlngvgnfrasdndrvidpgkvetltirrlhiprfylfy
dlstlysltervkritvenskvflvpcllsqhlksleyldlsenlmveeylknsacedaw
pslqtlilrqnhlaslektgetlltlknltnidisknsfhsmpetcqwpekmkylnlsst
rihsvtgcipktleildvsnnnlnlfslnlpqlkelyisrnklmtlpdasllpmllvlki
srnqlksvpdgifdrltslqkiwlhtnpwdcscpridylsrwlnknsqkeqgsakcsgsg
kpvrsiicp

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6nigD (D:)
mphtlwmvwvlgviislskeessnqaslscdrngickgssgslnsipsglteavksldls
nnrityisnsdlqrcvnlqalvltsngintieedsfsslgslehldlsynylsnlssswf
kplssltflnllgnpyktlgetslfshltklqilrvgnmdtftkiqrkdfagltfleele
idasdlqsyepkslksiqnvshlilhmkqhillleifvdvtssveclelrdtdldtfhfs
elstgetnslikkftfrnvkitdeslfqvmkllnqisgllelefddctlngvgnfrasdn
drvidpgkvetltirrlhiprfylfydlstlysltervkritvenskvflvpcllsqhlk
sleyldlsenlmveeylknsacedawpslqtlilrqnhlaslektgetlltlknltnidi
sknsfhsmpetcqwpekmkylnlsstrihsvtgcipktleildvsnnnlnlfslnlpqlk
elyisrnklmtlpdasllpmllvlkisrnqlksvpdgifdrltslqkiwlhtnpwdcscp
ridylsrwlnknsqkeqgsakcsgsgkpvrsiicpt

    Sequence, based on observed residues (ATOM records):
    >6nigD (D:)
slscdrngickgssgslnsipsglteavksldlsnnrityisnsdlqrcvnlqalvltsn
gintieedsfsslgslehldlsynylsnlssswfkplssltflnllgnpyktlgetslfs
hltklqilrvgnmdtftkiqrkdfagltfleeleidasdlqsyepkslksiqnvshlilh
mkqhillleifvdvtssveclelrdtdldtfhfselstgetnslikkftfrnvkitdesl
fqvmkllnqisgllelefddctlngvgnfrasdvidpgkvetltirrlhiprfylfydls
tlysltervkritvenskvflvpcllsqhlksleyldlsenlmveeylknsacedawpsl
qtlilrqnhlaslektgetlltlknltnidisknsfhsmpetcqwpekmkylnlsstrih
svtgcipktleildvsnnnlnlfslnlpqlkelyisrnklmtlpdasllpmllvlkisrn
qlksvpdgifdrltslqkiwlhtnpwdcscpridylsrwlnknsqkeqgsakcsgsgkpv
rsiicp