PDB entry 6ni2

View 6ni2 on RCSB PDB site
Description: stabilized beta-arrestin 1-v2t subcomplex of a gpcr-g protein-beta- arrestin mega-complex
Deposited on 2018-12-26, released 2019-11-20
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 4 Å
R-factor: N/A
AEROSPACI score: 0.05 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nanobody 32
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6NI2 (0-End)
  • Chain 'B':
    Compound: beta-arrestin-1
    Species: Bos taurus [TaxId:9913]
    Gene: ARRB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Fab30 heavy chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6NI2
  • Chain 'L':
    Compound: Fab30 light chain
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6NI2 (0-End)
  • Chain 'V':
    Compound: Vasopressin V2 receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: AVPR2, ADHR, DIR, DIR3, V2R
    Database cross-references and differences (RAF-indexed):
  • Heterogens: SEP, TPO

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ni2A (A:)
qvqlqesggglvqaggslrlscvvsgfffdtvtmawyrrapgkhrelvasataggtttya
dsvkdrftisrdnakntvylqmnslkpedtavyycntfvrslswgqgtqvtvsshhhhhh
epea

    Sequence, based on observed residues (ATOM records):
    >6ni2A (A:)
qvqlqesggglvqaggslrlscvvsgfffdtvtmawyrrapgkhrelvasataggtttya
dsvkdrftisrdnakntvylqmnslkpedtavyycntfvrslswgqgtqvtvs

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ni2B (B:)
mgdkgtrvfkkaspngkltvylgkrdfvdhidlvepvdgvvlvdpeylkerrvyvtltca
frygredldvlgltfrkdlfvanvqsfppapedkkpltrlqerlikklgehaypftfeip
pnlpcsvtlqpgpedtgkacgvdyevkafcaenleekihkrnsvrlvirkvqyaperpgp
qptaettrqflmsdkplhleasldkeiyyhgepisvnvhvtnntnktvkkikisvrqyad
iclfntaqykcpvameeaddtvapsstfckvytltpflannrekrglaldgklkhedtnl
asstllreganreilgiivsykvkvklvvsrggllgdlassdvavelpftlmhpkpkeep
phrevpehetpvdtnlieldtndddivfedfar

    Sequence, based on observed residues (ATOM records):
    >6ni2B (B:)
trvfkkaspngkltvylgkrdfvdhidlvepvdgvvlvdpeylkerrvyvtltcafrygr
edldvlgltfrkdlfvanvqsfppapedkkpltrlqerlikklgehaypftfeippnlpc
svtlqpgpedtgkacgvdyevkafcaenleekihkrnsvrlvirkvqyaperpgpqptae
ttrqflmsdkplhleasldkeiyyhgepisvnvhvtnntnktvkkikisvrqyadiclfn
taqykcpvameeaddtvapsstfckvytltpflannrekrglaldgklkhedtnlasstl
lrereilgiivsykvkvklvvsrggllgdlassdvavelpftlmhpkpkeepp

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6ni2H (H:)
eisevqlvesggglvqpggslrlscaasgfnvysssihwvrqapgkglewvasissyygy
tyyadsvkgrftisadtskntaylqmnslraedtavyycarsrqfwysgldywgqgtlvt
vssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavl
qssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdkthhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6ni2H (H:)
vqlvesggglvqpggslrlscaasgfnvysssihwvrqapgkglewvasissyygytyya
dsvkgrftisadtskntaylqmnslraedtavyycarsrqfwysgldywgqgtlvtv

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6ni2L (L:)
sdiqmtqspsslsasvgdrvtitcrasqsvssavawyqqkpgkapklliysasslysgvp
srfsgsrsgtdftltisslqpedfatyycqqykyvpvtfgqgtkveikrtvaapsvfifp
psdsqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstl
tlskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records):
    >6ni2L (L:)
sdiqmtqspsslsasvgdrvtitcrasqsvssavawyqqkpgkapklliysasslysgvp
srfsgsrsgtdftltisslqpedfatyycqqykyvpvtfgqgtkvei

  • Chain 'V':
    Sequence, based on SEQRES records:
    >6ni2V (V:)
argrtppslgpqdescttassslakd

    Sequence, based on observed residues (ATOM records):
    >6ni2V (V:)
descttassslakd