PDB entry 6ngz

View 6ngz on RCSB PDB site
Description: Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: nitric oxide synthase inhibitor complex heme enzyme, OXIDOREDUCTASE, oxidoreductase-oxidoreductase inhibitor complex
Deposited on 2018-12-21, released 2019-03-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nitric oxide synthase, brain
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Nos1, Bnos
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ngza_
  • Chain 'B':
    Compound: Nitric oxide synthase, brain
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Nos1, Bnos
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ngzb_
  • Heterogens: HEM, H4B, KPJ, ACT, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ngzA (A:)
cprflkvknwetdvvltdtlhlkstletgctehicmgsimlpsqhtrkpedvrtkdqlfp
lakefldqyyssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcv
griqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwn
sqliryagykqpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqi
ppelvlevpirhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvr
dycdnsrynileevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsate
sfikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvw
kg

    Sequence, based on observed residues (ATOM records): (download) 
    >6ngzA (A:)
rflkvknwetdvvltdtlhlkstletgctehicmgsimlpsqhtrvrtkdqlfplakefl
dqyyssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgriqws
klqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliry
agykqpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqippelvl
evpirhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdycdns
rynileevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhm
eneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvw

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ngzB (B:)
cprflkvknwetdvvltdtlhlkstletgctehicmgsimlpsqhtrkpedvrtkdqlfp
lakefldqyyssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcv
griqwsklqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwn
sqliryagykqpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqi
ppelvlevpirhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvr
dycdnsrynileevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsate
sfikhmeneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvw
kg

    Sequence, based on observed residues (ATOM records): (download) 
    >6ngzB (B:)
rflkvknwetdvvltdtlhlkstletgctehicmgsimlpsqhtrvrtkdqlfplakefl
dqyyssikrfgskahmdrleevnkeieststyqlkdteliygakhawrnasrcvgriqws
klqvfdardcttahgmfnyicnhvkyatnkgnlrsaitifpqrtdgkhdfrvwnsqliry
agykqpdgstlgdpanvqfteiciqqgwkaprgrfdvlplllqangndpelfqippelvl
evpirhpkfdwfkdlglkwyglpavsnmlleigglefsacpfsgwymgteigvrdycdns
rynileevakkmdldmrktsslwkdqalveiniavlysfqsdkvtivdhhsatesfikhm
eneyrcrggcpadwvwivppmsgsitpvfhqemlnyrltpsfeyqpdpwnthvwkg