SCOPe 2.08: Structural Classification of Proteins

PDB entry 6nay

View 6nay on RCSB PDB site
Description: Crystal structure of Neisseria meningitidis ClpP protease E31A+E58A activated double mutant
Class: hydrolase
Keywords: Serine protease, antibiotic, HYDROLASE
Deposited on 2018-12-06, released 2019-11-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-29, with a file datestamp of 2020-01-24.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Chain 'B':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Chain 'C':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayc_
Chain 'D':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayd_
Chain 'E':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6naye_
Chain 'F':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9 (Start-216)
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayf_
Chain 'G':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayg_
Chain 'H':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayh_
Chain 'I':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayi_
Chain 'J':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayj_
Chain 'K':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayk_
Chain 'L':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayl_
Chain 'M':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6naym_
Chain 'N':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayn_
Chain 'O':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayo_
Chain 'P':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayp_
Chain 'Q':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayq_
Chain 'R':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayr_
Chain 'S':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nays_
Chain 'T':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayt_
Chain 'U':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayu_
Chain 'V':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayv_
Chain 'W':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayw_
Chain 'X':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayx_
Chain 'Y':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayy_
Chain 'Z':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayz_
Chain 'a':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6naya_
Chain 'b':
Compound: ATP-dependent Clp protease proteolytic subunit
Species: Neisseria meningitidis [TaxId:487]
Gene: CLPP
Database cross-references and differences (RAF-indexed):
- Uniprot A0A0H5Q9L9
  - engineered mutation (43)
  - engineered mutation (70)
Domains in SCOPe 2.08: d6nayb_
Heterogens: HOH

PDB Chain Sequences:

Chain 'A':
No sequence available.
Chain 'B':
No sequence available.

Chain 'C':
Sequence, based on SEQRES records: (download)

>6nayC (C:)
hhhhhhenlyfqgmsfdnylvptvieqsgrgerafdiysrllkarivflvgpvtdesanl
vvaqllflesanpdkdiffyinspggsvtagmsiydtmnfikpdvstlclgqaasmgafl
lsagekgkrfalpnsrimihqplisgglggqasdieiharellkikeklnrlmakhcdrd
ladlerdtdrdnfmsaeeakeyglidqilenraslrl