PDB entry 6n9o

View 6n9o on RCSB PDB site
Description: crystal structure of human gsdmd
Deposited on 2018-12-03, released 2019-06-05
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Gasdermin-D
    Species: Homo sapiens [TaxId:9606]
    Gene: GSDMD, DFNA5L, GSDMDC1, FKSG10
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Gasdermin-D
    Species: Homo sapiens [TaxId:9606]
    Gene: GSDMD, DFNA5L, GSDMDC1, FKSG10
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Gasdermin-D
    Species: Homo sapiens [TaxId:9606]
    Gene: GSDMD, DFNA5L, GSDMDC1, FKSG10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P57764 (1-End)
      • conflict (281)
  • Chain 'D':
    Compound: Gasdermin-D
    Species: Homo sapiens [TaxId:9606]
    Gene: GSDMD, DFNA5L, GSDMDC1, FKSG10
    Database cross-references and differences (RAF-indexed):
    • Uniprot P57764
      • conflict (281)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6n9oA (A:)
smgsafervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnl
sikdilepdaaepdvqrgrsfhfydamdgqiqgsvelaapgqakiaggaavsdssstsmn
vyslsvdpntwqtllherhlrqpehkvlqqlrsrgdnvyvvtevlqtqkevevtrthkre
gsgrfslpgatclqgegqghlsqkktvtipsgstlafrvaqlvidsdldvllfpdkkqrt
fqppatghkrstsegawpqlpsglsmmrclhnfltdgvpaelaftedfqglraevetisk
elelldrelcqllleglegvlrdqlalraleealeqgqslgpvepldgpagavleclvls
sgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgplelvgslleqsapwqers
tmslppgllgnswgegapawvlldecglelgedtphvcwepqaqgrmcalyaslallsgl
sqeph

    Sequence, based on observed residues (ATOM records):
    >6n9oA (A:)
safervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnlsik
dilepdaydamdgqiqgsvesmnvyslsvdpntwqtllherhlrqpehkvlqqlrsrgdn
vyvvtevlqtqkevevttvtipsgstlafrvaqlvidsdldvllfpdkkqrtfqtedfqg
lraevetiskelelldrelcqllleglegvlrdqlalraleealeqgqslgpvepldgpa
gavleclvlssgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgplelvgsll
eqsapwqerstmslppgllgnswgegapawvlldecglelgedtphvcwepqaqgrmcal
yaslallsgls

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6n9oB (B:)
smgsafervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnl
sikdilepdaaepdvqrgrsfhfydamdgqiqgsvelaapgqakiaggaavsdssstsmn
vyslsvdpntwqtllherhlrqpehkvlqqlrsrgdnvyvvtevlqtqkevevtrthkre
gsgrfslpgatclqgegqghlsqkktvtipsgstlafrvaqlvidsdldvllfpdkkqrt
fqppatghkrstsegawpqlpsglsmmrclhnfltdgvpaelaftedfqglraevetisk
elelldrelcqllleglegvlrdqlalraleealeqgqslgpvepldgpagavleclvls
sgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgplelvgslleqsapwqers
tmslppgllgnswgegapawvlldecglelgedtphvcwepqaqgrmcalyaslallsgl
sqeph

    Sequence, based on observed residues (ATOM records):
    >6n9oB (B:)
safervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnlsik
dilepdydamdgqiqgssmnvyslsvdpntwqtllherhlrqpehkvlqqlrsrgdnvyv
vtevlqtqkevevtvtipsgstlafrvaqlvidsdldvllfpdkkqrtfqftedfqglra
evetiskelelldrelcqllleglegvlrdqlalraleealeqgqslgpvepldgpagav
leclvlssgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgplelvgslleqs
apwqerstmslppgllgnswgegapawvlldecglelgedtphvcwepqaqgrmcalyas
lallsglsq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6n9oC (C:)
smgsafervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnl
sikdilepdaaepdvqrgrsfhfydamdgqiqgsvelaapgqakiaggaavsdssstsmn
vyslsvdpntwqtllherhlrqpehkvlqqlrsrgdnvyvvtevlqtqkevevtrthkre
gsgrfslpgatclqgegqghlsqkktvtipsgstlafrvaqlvidsdldvllfpdkkqrt
fqppatghkrstsegawpqlpsglsmmrclhnfltdgvpaelaftedfqglraevetisk
elelldrelcqllleglegvlrdqlalraleealeqgqslgpvepldgpagavleclvls
sgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgplelvgslleqsapwqers
tmslppgllgnswgegapawvlldecglelgedtphvcwepqaqgrmcalyaslallsgl
sqeph

    Sequence, based on observed residues (ATOM records):
    >6n9oC (C:)
mgsafervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnls
ikdilepdamdgqiqgsvelaapgsmnvyslsvdpntwqtllherhlrqpehkvlqqlrs
rgdnvyvvtevlqtqkevevktvtipsgstlafrvaqlvidsdldvllfpdkkqrtfqel
aftedfqglraevetiskelelldrelcqllleglegvlrdqlalraleealeqgqslgp
vepldgpagavleclvlssgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgp
lelvgslleqsapwqerstmslppgllgnswgegapawvlldecglelgedtphvcwepq
aqgrmcalyaslallsgls

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6n9oD (D:)
smgsafervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnl
sikdilepdaaepdvqrgrsfhfydamdgqiqgsvelaapgqakiaggaavsdssstsmn
vyslsvdpntwqtllherhlrqpehkvlqqlrsrgdnvyvvtevlqtqkevevtrthkre
gsgrfslpgatclqgegqghlsqkktvtipsgstlafrvaqlvidsdldvllfpdkkqrt
fqppatghkrstsegawpqlpsglsmmrclhnfltdgvpaelaftedfqglraevetisk
elelldrelcqllleglegvlrdqlalraleealeqgqslgpvepldgpagavleclvls
sgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgplelvgslleqsapwqers
tmslppgllgnswgegapawvlldecglelgedtphvcwepqaqgrmcalyaslallsgl
sqeph

    Sequence, based on observed residues (ATOM records):
    >6n9oD (D:)
gsafervvrrvvqeldhggefipvtslqsstgfqpyclvvrkpssswfwkprykcvnlsi
kdilepdaydamdgqiqgsvetsmnvyslsvdpntwqtllherhlrqpehkvlqqlrsrg
dnvyvvtevlqtqkevevttvtipsgstlafrvaqlvidsdldvllfpdkkqrtfqplaf
tedfqglraevetiskelelldrelcqllleglegvlrdqlalraleealeqgqslgpve
pldgpagavleclvlssgmlvpelaipvvyllgaltmlsetqhkllaealesqtllgple
lvgslleqsapwqerstmslppgllgnswgegapawvlldecglelgedtphvcwepqaq
grmcalyaslallsgls