PDB entry 6n8x

View 6n8x on RCSB PDB site
Description: Hsp90-alpha bound to PU-11-trans
Class: chaperone/chaperone inhibitor
Keywords: HSP90, Inhibitor, Cancer, Cytosol, CHAPERONE, chaperone-chaperone inhibitor complex
Deposited on 2018-11-30, released 2019-07-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-04, with a file datestamp of 2019-11-29.
Experiment type: XRAY
Resolution: 1.49 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Heat shock protein HSP 90-alpha
    Species: Homo sapiens [TaxId:9606]
    Gene: HSP90AA1, HSP90A, HSPC1, HSPCA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6n8xa_
  • Heterogens: KFY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6n8xA (A:)
mgsshhhhhhssglvprgshmpeetqtqdqpmeeeevetfafqaeiaqlmsliintfysn
keiflrelisnssdaldkiryesltdpskldsgkelhinlipnkqdrtltivdtgigmtk
adlinnlgtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvitkhnddeqy
awessaggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsqfigypitl
fvekerdkevsddeae

    Sequence, based on observed residues (ATOM records): (download) 
    >6n8xA (A:)
evetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgke
lhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqfg
vgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqt
eyleerrikeivkkhsqfigypitlfveke