PDB entry 6n7r

View 6n7r on RCSB PDB site
Description: saccharomyces cerevisiae spliceosomal e complex (act1)
Deposited on 2018-11-28, released 2019-09-18
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: U1 small nuclear ribonucleoprotein 70 kDa homolog
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: u1 small nuclear ribonucleoprotein c
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: U1 small nuclear ribonucleoprotein A
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: U1 small nuclear ribonucleoprotein component PRP42
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Pre-mRNA-processing factor 39
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Protein NAM8
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: 56 kDa U1 small nuclear ribonucleoprotein component
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: U1 small nuclear ribonucleoprotein component SNU71,U1 small nuclear ribonucleoprotein component SNU71,Snu71
    Species: Saccharomyces cerevisiae S288c [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P53207 (0-50)
    • PDB 6N7R (51-88)
  • Chain 'I':
    Compound: Protein LUC7
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: Small nuclear ribonucleoprotein-associated protein B
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Small nuclear ribonucleoprotein Sm D1
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: Small nuclear ribonucleoprotein Sm D2
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: Small nuclear ribonucleoprotein Sm D3
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: Small nuclear ribonucleoprotein E
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: Small nuclear ribonucleoprotein F
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: Small nuclear ribonucleoprotein G
    Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) [TaxId:559292]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: U1 snRNA
    Species: Saccharomyces cerevisiae [TaxId:4932]
  • Chain 'r':
    Compound: ACT1 pre-mRNA
    Species: Saccharomyces cerevisiae S288c, synthetic [TaxId:559292]
  • Heterogens: ZN

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6n7rA (A:)
mnynlskypddvsrlfkprpplsykrptdypyakrqtnpnitgvanllstslkhymeefp
egspnnhlqryediklskiknaqlldrrlqnwnpnvdphikdtdpyrtifigrlpydlde
ielqkyfvkfgeiekirivkdkitqkskgyafivfkdpisskmafkeigvhrgiqikdri
civdiergrtvkyfkprrlggglggrgysnrdsrlpgrfasastsnpaernyaprlprre
tsssaysadrygsstldaryrgnrpllsaatptaavtsvyksrnsrtresqpapkeapdy

    Sequence, based on observed residues (ATOM records):
    >6n7rA (A:)
mnynlskypddvsrlfkprpplsykrptdypyakrqtnpnitgvanllstslkhymeefp
egspnnhlqryediklskiknaqlldrrlqnpnvdphikdtdpyrtifigrlpydldeie
lqkyfvkfgeiekirivkdkitqkskgyafivfkdpisskmafkeigvhrgiqikdrici
vdierg

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6n7rB (B:)
mtryyceychsylthdtlsvrkshlvgknhlritadyyrnkardiinkhnhkrrhigkrg
rkerenssqnetlkvtclsnkekrhimhvkkmnqkelaqtsidtlkllydgspgyskvfv
danrfdigdlvkasklpqraneksahhsfkqtsrsrdetcesnpfprlnnpkkleppkil
sqwsntipktsifysvdilqttikeskkrmhsdgirkpssangykrrrygn

    Sequence, based on observed residues (ATOM records):
    >6n7rB (B:)
ryyceychsylthdtlsvrkshlvgknhlritadyyrnkardiinkhnhkrrhigkrgrk
erenssqnetlkvtclsnkekrhimhvkkmnqkelaqtsidtlkllydgspgyskvfvda
nrfdigdlvkasklpqraneksahhsfkqtsrsrdetcesnpfprlnnpkkleppkilsq
wsntipktsifysvd

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6n7rC (C:)
msalyfqnlpsrpankenytrlllkhinpnnkyainpslplphnklqissqplmllddqm
gllevsisrsskmtnqafltfvtqeeadrflekytttalkvqgrkvrmgkartnsllgls
iemqkkkgndetynldikkvlkarklkrklrsddicakkfrlkrqirrlkhklrsrkvee
aeidrivkefetrrlenmksqqenlkqsqkplkrakvsntmenppnkvlliqnlpsgtte
qllsqilgnealveirlvsvrnlafveyetvadatkiknqlgstyklqnndvtigfakgr
ripglinpwkrrwkknfiavsaanrfkkisssgaldydipttasenlyfq

    Sequence, based on observed residues (ATOM records):
    >6n7rC (C:)
msalyfqnlpsrpankenytrlllkhinpnnkyainpslplphnklllddqmgllevsis
rsskmtnqafltfvtqeeadrflekytttalkvqgrkvrmgkartnsllglsiemqkynl
dikkvlkarklkr

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6n7rD (D:)
mdkytalihdenfstltlnvsrypkslaywekllnyivkasapickstepqllklircty
ssmlnefpylenyyidfalleyklgnvsmshkifqrglqafnqrslllwtsylkfcnnvi
shqkqlfkkyetaeeyvglhffsgefwdlyleqissrctsskkywnvlrkileiplhsfs
kfyalwlqriddimdlkqlsqltskdellkklkidinysgrkgpylqdakkklkkitkem
ymvvqyqvleiysifeskiyinyytspetlvssdeietwikyldytitlqtdslthlnfq
rallplahydlvwikyskwlinskndllgaknvllmglkfslkkteiikllysvicklne
yvllrnllekiessysdnvenvddfeifwdylqfktfcqnslyssrysdsqsngllnkel
fdkvwkrlsckekksgqeillnnlvqfyskdtvefveknifqkiiefgweyylqngmfwn
cycrliyfdtsrsyldkrqyivrkiwpqidkkfaqsvlpsltefcesyfpeemdtleemf
teep

    Sequence, based on observed residues (ATOM records):
    >6n7rD (D:)
mdkytalihdenfstltlnvsrypkslaywekllnyivkasapickstepqllklircty
ssmlnefpylenyyidfalleyklgnvsmshkifqrglqafnqrslllwtsylkfcnnvi
shqkqlfkkyetaeeyvglhffsgefwdlyleqissrctsskkywnvlrkileiplhsfs
kfyalwlqriddimdlkqlsqltskdellkklkidinysgrkgpylqdakkklkkitkem
ymvvqyqvleiysifeskiyinyytspetlvssdeietwikyldytitlqtdslthlnfq
rallplahydlvwikyskwlinskndllgaknvllmglkfslkkteiikllysvicklne
yvllrnllekiessysdnvenvddfeifwdylqfktfcqnslyssrysdsqsngllnkel
fdkvwkrlsckekksgqeillnnlvqfyskdtvefveknifqkiiefgweyylqngmfwn
cycrliyfdtsrsyldkrqyivrkiwpqidkkfaqsvlpsltefcesyfpeemdtleemf
t

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6n7rE (E:)
mpdetnftiedieprpdalrgldtqflqdntalvqayrgldwsdissltqmvdvieqtvv
kygnpndsiklaletilwqilrkypllfgfwkrfatieyqlfglkksiavlatsvkwfpt
slelwcdylnvlcvnnpnetdfirnnfeiakdligkqflshpfwdkfiefevgqknwhnv
qriyeyiievplhqyarfftsykkflneknlkttrnidivlrktqttvneiwqfeskikq
pffnlgqvlnddlenwsrylkfvtdpsksldkefvmsvfdrclipclyhentwmmyikwl
tkknisdevvvdiyqkantflpldfktlrydflrflkrkyrsnntlfnnifnetvsrylk
iwpndillmteylcmlkrhsfknsldqspkeilekqtsftkiletsitnyinnqidakvh
lqtlindknlsivvvelikttwlvlknnmqtrkyfnlyqkniliknsvpfwltyykfeks
nvnftklnkfirelgveiylpttvmndiltdyktfylthsnivtyessiidsntfdpily
pelkmsnpkydpvlnttanvdwhkktewkeaghigitterpqisnsiiecnsgtliqkpi
slpnfrnlekinqvkindlyteeflkegk

    Sequence, based on observed residues (ATOM records):
    >6n7rE (E:)
alrgldtqflqdntalvqayrgldwsdissltqmvdvieqtvvkygnpndsiklaletil
wqilrkypllfgfwkrfatieyqlfglkksiavlatsvkwfptslelwcdylnvlcvnnp
netdfirnnfeiakdligkqflshpfwdkfiefevgqknwhnvqriyeyiievplhqyar
fftsykkflneknlkttrnidivlrktqttvneiwqfeskikqpffnlgqvlnddlenws
rylyhentwmmyikwltkknisdevvvdiyqkantflpldfktlrydflrflkrkyrsnn
tlfnnifnetvsrylkiwpndillmteylcmlkrhsfknsldqspkeilekqtsftkile
tsitnyinnqidakvhlqtlindknlsivvvelikttwlvlknnmqtrkyfnlyqknili
knsvpfwltyykfeksnvnftklnkfirelgveiylpttvmndiltdyktfylthsnivt
yessiidsntfdpilypelkmsnpkydpvdwhkktewkeaghigitterpqisnsiiecn
sgtliqkpislpnfrnlekinqvkindlyteeflke

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6n7rF (F:)
msykqttyypsrgnlvrndsspytntissetnnsstsvlslqgasnvslgttgnqlymgd
ldptwdkntvrqiwaslgeaninvrmmwnntlnngsrssmgpknnqgycfvdfpssthaa
nallkngmlipnfpnkklklnwatssysnsnnslnnvksgnncsifvgdlapnvtesqlf
elfinryastshakivhdqvtgmskgygfvkftnsdeqqlalsemqgvflngraikvgpt
sgqqqhvsgnndynrsssslnnenvdsrflskgqsflsngnnnmgfkrnhmsqfiypvqq
qpslnhftdpnnttvfigglsslvtedelrayfqpfgtivyvkipvgkccgfvqyvdrls
aeaaiagmqgfpiansrvrlswgrsakqtallqqamlsnslqvqqqqpglqqpnygyips
stceapvlpdnnvsstmlpgcqilnysnpyananglgsnnfsfysnnnatntqatsllad
tssmdlsgtggqqvimqgseavvnstnamlnrleqgsngfmfa

    Sequence, based on observed residues (ATOM records):
    >6n7rF (F:)
msqfiypvqqqpslnhftdpnnttvfigglsslvtedelrayfqpfgtivyvkipvgkcc
gfvqyvdrlsaeaaiagmqgfpiansrvrlswgrsakqtallqqamlsnslqvqqqqpgl
qqpnygyipsstceanvsstmlpgcqilnysnpqqvimqgseavvnstnamlnrleqgsn
gfmfa

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6n7rG (G:)
mrprrrglayhhtkpkgqlsqghypttsndgqrrkvgnseafqsfdiwknldrirstkkn
agqfikgsllilpmrtedkqqfdecmdelhkyiskdilrcypqkeqkdegmlfyivlkdf
nildscfvlsvllafqkrlwmapseksyfrvpkninltgsfylpknietgrghiitsyrr
eqpsssivevgfnvvpdfqqfqvkachvskfmnelsnffsqvefgkceanvinyfkreyn
rtysqislalyelpligdglfdiksyisktrpiietskaqmikhisemkayneisglqgd
qfprqqrplsnspssnsisssqtieagatsyqtqpqrhavnkpsnvlnssnrhsgpktfe
dgrysegnkpgfmtqdeikqhcigtikasmdavkkkssyqilktyvrcprqnyidivyqn
lndlrsktncnivvlnlnnlhesqmwleslnttnytifaqaphpstirvisiggvgeyiv
kalelilnileh

    Sequence, based on observed residues (ATOM records):
    >6n7rG (G:)
sfdiwknldrirstkknagqfikgsllilpmrtedkqqfdecmdelhkyiskdilrcypq
kmlfyivlkdfnildscfvlsvllafqkrlwmapseksyfrvpkninltgsfylpkniet
gssivevgfnvvpdfqqfqvkachvskfmnelsnffsqvefgkceanvinyfkreynrty
sqislalyelpligdglfdiksyisktrpiietskaqmikhisemkayneis

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >6n7rH (H:)
mrdivfvspqlylssqegwksdsaksgfipilkndlqrfqdslkhivdarnsxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxx

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6n7rI (I:)
mstmstpaaeqrklveqlmgrdfsfrhnryshqkrdlglhdpkicksylvgecpydlfqg
tkqslgkcpqmhltkhkiqyerevkqgktfpefereylailsrfvnecngqisvalqnlk
htaeermkiqqvteeldvldvriglmgqeidsliradevsmgmlqsvklqeliskrkeva
krvrnitenvgqsaqqklqvcevcgaylsrldtdrrladhflgkihlgyvkmredydrlm
knnrttnasktattlpgrrfv

    Sequence, based on observed residues (ATOM records):
    >6n7rI (I:)
mstpaaeqrklveqlmhdpkicksylvgecpydlfqgtkqslgkcpqmhltkhkiqyere
vkqgktfpefereylailsrfvnecngqisvalqnlkhqklqvcevcgaylsrldtdrrl
adhflgkihlgyvkmredydrlmknnr

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6n7rK (K:)
mskiqvahssrlanlidyklrvltqdgrvyigqlmafdkhmnlvlnecieervpktqldk
lrprkdskdgttlnikvekrvlgltilrgeqilstvvedkpllskkerlvrdkkekkqaq
kqtklrkekekkpgkiakpntanakhtssnsreiaqpsssrynggndniganrsrfnnea
ppqtrkfqpppgfkrk

    Sequence, based on observed residues (ATOM records):
    >6n7rK (K:)
iqvahssrlanlidyklrvltqdgrvyigqlmafdkhmnlvlnecieervpktqldklrp
rgttlnikvekrvlgltilrgeqilstvvedkpllskkerlvrdkkekkqaqkqtklrke
kekk

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6n7rL (L:)
mklvnflkklrneqvtielkngttvwgtlqsvspqmnailtdvkltlpqprlnklnsngi
amaslyltggqqptasdniaslqyinirgntirqiilpdslnldsllvdqkqlnslrrsg
qiandpskkrrrdfgapankrprrgl

    Sequence, based on observed residues (ATOM records):
    >6n7rL (L:)
mklvnflkklrneqvtielkngttvwgtlqsvspqmnailtdvkltlpqprlnklnsngi
amaslyltggqqptasdniaslqyinirgntirqiilpdslnldsllvdqkqlnslrrs

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6n7rM (M:)
mssqiidrpkhelsraeleeleefefkhgpmslindamvtrtpviislrnnhkiiarvka
fdrhcnmvlenvkelwtekkgknvinrerfisklflrgdsvivvlktpve

    Sequence, based on observed residues (ATOM records):
    >6n7rM (M:)
ssqiidrpkhelsraeleeleefefkhgpmslindamvtrtpviislrnnhkiiarvkaf
drhcnmvlenvkelwtekkgknvinrerfisklflrgdsvivvlktp

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6n7rN (N:)
mtmngipvkllneaqghivslelttgatyrgklvesedsmnvqlrdviatepqgavthmd
qifvrgsqikfivvpdllknaplfkknssrpmppirgpkrr

    Sequence, based on observed residues (ATOM records):
    >6n7rN (N:)
gipvkllneaqghivslelttgatyrgklvesedsmnvqlrdviatepqgavthmdqifv
rgsqikfivvpdllknaplfkknssrpmppi

  • Chain 'O':
    Sequence, based on SEQRES records:
    >6n7rO (O:)
msnkvktkamvppincifnflqqqtpvtiwlfeqigirikgkivgfdefmnvvideavei
pvnsadgkedvekgtplgkillkgdnitlitsad

    Sequence, based on observed residues (ATOM records):
    >6n7rO (O:)
amvppincifnflqqqtpvtiwlfeqigirikgkivgfdefmnvvideaveipvekgtpl
gkillkgdnitlits

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6n7rP (P:)
msessdisamqpvnpkpflkglvnhrvgvklkfnsteyrgtlvstdnyfnlqlneaeefv
agvshgtlgeifircnnvlyirelpn

    Sequence, based on observed residues (ATOM records):
    >6n7rP (P:)
pvnpkpflkglvnhrvgvklkfnsteyrgtlvstdnyfnlqlneaeefvagvshgtlgei
fircnnvlyirelp

  • Chain 'Q':
    Sequence, based on SEQRES records:
    >6n7rQ (Q:)
mvstpelkkymdkkillningsrkvagilrgydiflnvvlddameingedpannhqlglq
tvirgnsiislealdai

    Sequence, based on observed residues (ATOM records):
    >6n7rQ (Q:)
vstpelkkymdkkillningsrkvagilrgydiflnvvlddameinnnhqlglqtvirgn
siislealdai

  • Chain 'R':
    No sequence available.

  • Chain 'r':
    No sequence available.