PDB entry 6n7e

View 6n7e on RCSB PDB site
Description: crystal structure of the cytosolic domain of human cnnm2 in complex with amp-pnp and mg2+
Deposited on 2018-11-27, released 2019-12-04
The last revision was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metal transporter CNNM2,Metal transporter CNNM2
    Species: Homo sapiens [TaxId:9606]
    Gene: Cnnm2, Acdp2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H8M5
    • Uniprot Q9H8M5 (Start-345)
      • expression tag (346-351)
  • Chain 'B':
    Compound: Metal transporter CNNM2,Metal transporter CNNM2
    Species: Homo sapiens [TaxId:9606]
    Gene: Cnnm2, Acdp2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H8M5
    • Uniprot Q9H8M5 (Start-345)
      • expression tag (346-352)
  • Chain 'C':
    Compound: Metal transporter CNNM2,Metal transporter CNNM2
    Species: Homo sapiens [TaxId:9606]
    Gene: Cnnm2, Acdp2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H8M5 (Start-294)
      • linker (295)
    • Uniprot Q9H8M5 (296-345)
      • expression tag (346-351)
  • Chain 'D':
    Compound: Metal transporter CNNM2,Metal transporter CNNM2
    Species: Homo sapiens [TaxId:9606]
    Gene: Cnnm2, Acdp2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9H8M5 (Start-294)
      • linker (295)
    • Uniprot Q9H8M5 (Start-345)
      • expression tag (346-349)
  • Heterogens: ANP, MG, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6n7eA (A:)
mkeelniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfege
rsnivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlai
vqrvnnegegdpfyevlgivtledvieeiikseildetdlytdnrtkkkvahrerkqdfs
afkqtdsemkvkispqlllamhrflateveafspsqmsekillrllkhpnviqelkydek
nkkapeyylyqrnkpvdyfvlilqgkveveagkegmkfeasafsyygvmaltaspvidav
tptlgssnnqlnssllqvyipdysvralsdlqfvkisrqqyqnalmlehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6n7eA (A:)
elniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfegersn
ivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlaivqy
evlgivtledvieeiikseildetdlytdnrtkfsafkqtdsemkvkispqlllamhrfl
ateveafspsqmsekillrllkhpnviqelkydeknkkapeyylyqrnkpvdyfvlilqg
kveveagkegmkfeasafsyygvmaltasqvyipdysvralsdlqfvkisrqqyqnalml
ehhhh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6n7eB (B:)
mkeelniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfege
rsnivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlai
vqrvnnegegdpfyevlgivtledvieeiikseildetdlytdnrtkkkvahrerkqdfs
afkqtdsemkvkispqlllamhrflateveafspsqmsekillrllkhpnviqelkydek
nkkapeyylyqrnkpvdyfvlilqgkveveagkegmkfeasafsyygvmaltaspvidav
tptlgssnnqlnssllqvyipdysvralsdlqfvkisrqqyqnalmlehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6n7eB (B:)
eelniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfegers
nivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlaivq
fyevlgivtledvieeiikseildetdlyfsafkqtdsemkvkispqlllamhrflatev
eafspsqmsekillrllkhpnviqelkydeknkkapeyylyqrnkpvdyfvlilqgkvev
eagkegmkfeasafsyygvmaltavyipdysvralsdlqfvkisrqqyqnalmlehhhhh

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6n7eC (C:)
mkeelniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfege
rsnivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlai
vqrvnnegegdpfyevlgivtledvieeiikseildetdlytdnrtkkkvahrerkqdfs
afkqtdsemkvkispqlllamhrflateveafspsqmsekillrllkhpnviqelkydek
nkkapeyylyqrnkpvdyfvlilqgkveveagkegmkfeasafsyygvmaltaspvidav
tptlgssnnqlnssllqvyipdysvralsdlqfvkisrqqyqnalmlehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6n7eC (C:)
elniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfegersn
ivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlaiivt
ledvieeiikseildetdlyafkqtdsemkvkispqlllamhrflateveafspsqmsek
illrllkhpnviqelkydeknkkapeyylyqrnkpvdyfvlilqgkveveagkegmkfea
safsyygvmaltaspvidnqlnssllqvyipdysvralsdlqfvkisrqqyqnalmlehh
hh

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6n7eD (D:)
mkeelniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfege
rsnivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlai
vqrvnnegegdpfyevlgivtledvieeiikseildetdlytdnrtkkkvahrerkqdfs
afkqtdsemkvkispqlllamhrflateveafspsqmsekillrllkhpnviqelkydek
nkkapeyylyqrnkpvdyfvlilqgkveveagkegmkfeasafsyygvmaltaspvidav
tptlgssnnqlnssllqvyipdysvralsdlqfvkisrqqyqnalmlehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6n7eD (D:)
elniiqgalelrtktvedvmtplrdcfmitgeaildfntmseimesgytripvfegersn
ivdllfvkdlafvdpddctplktitkfynhplhfvfndtkldamleefkkgkshlaivqf
yevlgivtledvieeiikseildetdlytdnrtkkkvahrerkqdfsafkqtdsemkvki
spqlllamhrflateveafspsqmsekillrllkhpnviqelkydeknkkapeyylyqrn
kpvdyfvlilqgkveveagkegmkfeasafsyygvmaltaspvllqvyipdysvralsdl
qfvkisrqqyqnalmlehh