PDB entry 6n7d

View 6n7d on RCSB PDB site
Description: Structure of the human JAK1 kinase domain with compound 54
Class: immune system
Keywords: jak1, il13, il-13, jak2, jak3, tyk2, immune system
Deposited on 2018-11-27, released 2019-04-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase JAK1
    Species: Homo sapiens [TaxId:9606]
    Gene: JAK1, JAK1A, JAK1B
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6n7da_
  • Heterogens: KF4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6n7dA (A:)
gdivsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkp
esggnhiadlkkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknk
nkinlkqqlkyavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdk
eyytvkddrdspvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmi
gpthgqmtvtrlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeal
lk

    Sequence, based on observed residues (ATOM records): (download) 
    >6n7dA (A:)
vdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkphiadlkkeieil
rnlyhenivkykgictgiklimeflpsgslkeylpknknkinlkqqlkyavqickgmdyl
gsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrdspvfwyapeclm
qskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvtrlvntlkegkrl
pcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk