PDB entry 6n6o

View 6n6o on RCSB PDB site
Description: Crystal structure of the human TTK in complex with an inhibitor
Class: signaling protein
Keywords: Protein Kinase Activity Protein Serine/Threonine/Tyrosine kinase activity ATP Binding Protein Phosphorylation Mitotic Cell Cycle Checkpoint Chromosome Separation, SIGNALING PROTEIN
Deposited on 2018-11-26, released 2019-05-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-22, with a file datestamp of 2019-05-17.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase TTK
    Species: Homo sapiens [TaxId:9606]
    Gene: TTK, MPS1, MPS1L1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6n6oa_
  • Heterogens: KE7, 1PE, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6n6oA (A:)
shnecisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrnei
aylnklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknml
eavhtihqhgivhsdlkpanflivdgmlklidfgianqmqpdttsvvkdsqvgtvnympp
eaikdmsssrengkskskispksdvwslgcilyymtygktpfqqiinqisklhaiidpnh
eiefpdipekdlqdvlkcclkrdpkqrisipellahpyvqiqtle

    Sequence, based on observed residues (ATOM records): (download) 
    >6n6oA (A:)
necisvkgriysilkqigsggsskvfqvlnekkqiyaikyvnleeadnqtldsyrneiay
lnklqqhsdkiirlydyeitdqyiymvmecgnidlnswlkkkksidpwerksywknmlea
vhtihqhgivhsdlkpanflivdgmlklidfgiantvnymppeaikdmskispksdvwsl
gcilyymtygktpfqqiinqisklhaiidpnheiefpdipekdlqdvlkcclkrdpkqri
sipellahpyvqiq