PDB entry 6n5d

View 6n5d on RCSB PDB site
Description: Broadly protective antibodies directed to a subdominant influenza hemagglutinin epitope
Class: viral protein/immune system
Keywords: influenza, antibody, complex, hemagglutinin, immunogen design, glycan, VIRAL PROTEIN-IMMUNE SYSTEM complex
Deposited on 2018-11-21, released 2019-06-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03437 (0-281)
      • conflict (151)
    Domains in SCOPe 2.08: d6n5da_
  • Chain 'B':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03437 (0-281)
      • conflict (151)
    Domains in SCOPe 2.08: d6n5db_
  • Chain 'C':
    Compound: antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Gene: HC
    Database cross-references and differences (RAF-indexed):
    • PDB 6N5D
    Domains in SCOPe 2.08: d6n5dc_
  • Chain 'D':
    Compound: Antibody Light Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6N5D
    Domains in SCOPe 2.08: d6n5dd1, d6n5dd2
  • Chain 'E':
    Compound: antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Gene: HC
    Database cross-references and differences (RAF-indexed):
    • PDB 6N5D
    Domains in SCOPe 2.08: d6n5de_
  • Chain 'F':
    Compound: Antibody Light Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6N5D
    Domains in SCOPe 2.08: d6n5df1, d6n5df2
  • Chain 'K':
    Compound: Hemagglutinin
    Species: Influenza A virus [TaxId:11320]
    Gene: HA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03437 (0-281)
      • conflict (151)
    Domains in SCOPe 2.08: d6n5dk_
  • Chain 'L':
    Compound: antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Gene: HC
    Database cross-references and differences (RAF-indexed):
    • PDB 6N5D
    Domains in SCOPe 2.08: d6n5dl_
  • Chain 'N':
    Compound: Antibody Light Chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6N5D
    Domains in SCOPe 2.08: d6n5dn1, d6n5dn2

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6n5dA (A:)
tnatelvqssstgkicnnphrildgidctlidallgdphcdvfqnetwdlfverskafsn
cypydvpdyaslrslvassgtlefitegftwtgvtqnggsnackrgpgsgffsrlnwltk
sgstypvlnvtmpnndnfdklyiwgihhpstdqeqtslyvqasgrvtvstrrsqqtiipn
igsrpwvrglssrisiywtivkpgdvlvinsngnliaprgyfkmrtgkssimrsdapidt
cisecitpngsipndkpfqnvnkitygacpkyvkqntlklat

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6n5dB (B:)
tnatelvqssstgkicnnphrildgidctlidallgdphcdvfqnetwdlfverskafsn
cypydvpdyaslrslvassgtlefitegftwtgvtqnggsnackrgpgsgffsrlnwltk
sgstypvlnvtmpnndnfdklyiwgihhpstdqeqtslyvqasgrvtvstrrsqqtiipn
igsrpwvrglssrisiywtivkpgdvlvinsngnliaprgyfkmrtgkssimrsdapidt
cisecitpngsipndkpfqnvnkitygacpkyvkqntlklat

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6n5dC (C:)
asdvklvesgeglvkpggslklscaasgftfssydmswvrqtpekrlewvayissggdyi
yyadtvkgrftisrdnarntlylqmsslksedtamyyctrvgeydawfaywdqgtlvtvs
gastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkgsslevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6n5dC (C:)
vklvesgeglvkpggslklscaasgftfssydmswvrqtpekrlewvayissggdyiyya
dtvkgrftisrdnarntlylqmsslksedtamyyctrvgeydawfaywdqgtlvtvsgas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscd

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6n5dD (D:)
asqavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlfagliggtknrap
gvparfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpkgapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6n5dD (D:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlfagliggtknrapgv
parfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpkgapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6n5dE (E:)
asdvklvesgeglvkpggslklscaasgftfssydmswvrqtpekrlewvayissggdyi
yyadtvkgrftisrdnarntlylqmsslksedtamyyctrvgeydawfaywdqgtlvtvs
gastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkgsslevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6n5dE (E:)
vklvesgeglvkpggslklscaasgftfssydmswvrqtpekrlewvayissggdyiyya
dtvkgrftisrdnarntlylqmsslksedtamyyctrvgeydawfaywdqgtlvtvsgas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscd

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6n5dF (F:)
asqavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlfagliggtknrap
gvparfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpkgapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6n5dF (F:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlfagliggtknrapgv
parfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpkgapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6n5dK (K:)
tnatelvqssstgkicnnphrildgidctlidallgdphcdvfqnetwdlfverskafsn
cypydvpdyaslrslvassgtlefitegftwtgvtqnggsnackrgpgsgffsrlnwltk
sgstypvlnvtmpnndnfdklyiwgihhpstdqeqtslyvqasgrvtvstrrsqqtiipn
igsrpwvrglssrisiywtivkpgdvlvinsngnliaprgyfkmrtgkssimrsdapidt
cisecitpngsipndkpfqnvnkitygacpkyvkqntlklat

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6n5dL (L:)
asdvklvesgeglvkpggslklscaasgftfssydmswvrqtpekrlewvayissggdyi
yyadtvkgrftisrdnarntlylqmsslksedtamyyctrvgeydawfaywdqgtlvtvs
gastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkgsslevlfq

    Sequence, based on observed residues (ATOM records): (download) 
    >6n5dL (L:)
vklvesgeglvkpggslklscaasgftfssydmswvrqtpekrlewvayissggdyiyya
dtvkgrftisrdnarntlylqmsslksedtamyyctrvgeydawfaywdqgtlvtvsgas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscd

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >6n5dN (N:)
asqavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlfagliggtknrap
gvparfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpkgapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6n5dN (N:)
qavvtqesalttspgetvtltcrsstgavttsnyanwvqekpdhlfagliggtknrapgv
parfsgsligdkaaltitgaqtedeaiyfcalwysnhwvfgggtkltvlgqpkgapsvtl
fppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaassy
lsltpeqwkshrsyscqvthegstvektvapt