PDB entry 6n53

View 6n53 on RCSB PDB site
Description: Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidouridine monophosphate
Class: cytosolic protein
Keywords: Uridine-cytidine kinase 2, UCK2, Kinase, Complex, Azide, CYTOSOLIC PROTEIN
Deposited on 2018-11-21, released 2019-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-03-18, with a file datestamp of 2020-03-13.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Uridine-cytidine kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: UCK2, UMPK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6n53a_
  • Chain 'B':
    Compound: Uridine-cytidine kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: UCK2, UMPK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6n53b_
  • Heterogens: PO4, MG, GOL, UZR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6n53A (A:)
    gplgsmagdseqtlqnhqqpnggepfligvsggtasgkssvcakivqllgqnevdyrqkq
    vvilsqdsfyrvltseqkakalkgqfnfdhpdafdnelilktlkeitegktvqipvydfv
    shsrkeetvtvypadvvlfegilafysqevrdlfqmklfvdtdadtrlsrrvlrdiserg
    rdleqilsqyitfvkpafeefclptkkyadviiprgadnlvainlivqhiqdilnggpsk
    rqtngclngytpsrk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6n53A (A:)
    epfligvsggtasgkssvcakivqllgqnqkqvvilsqdsfyrvltseqkakalkgqfnf
    dhpdafdnelilktlkeitegktvqipvydfvshsrkeetvtvypadvvlfegilafysq
    evrdlfqmklfvdtdadtrlsrrvlrdisergrdleqilsqyitfvkpafeefclptkky
    adviiprgadnlvainlivqhiqdiln
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6n53B (B:)
    gplgsmagdseqtlqnhqqpnggepfligvsggtasgkssvcakivqllgqnevdyrqkq
    vvilsqdsfyrvltseqkakalkgqfnfdhpdafdnelilktlkeitegktvqipvydfv
    shsrkeetvtvypadvvlfegilafysqevrdlfqmklfvdtdadtrlsrrvlrdiserg
    rdleqilsqyitfvkpafeefclptkkyadviiprgadnlvainlivqhiqdilnggpsk
    rqtngclngytpsrk
    

    Sequence, based on observed residues (ATOM records): (download)
    >6n53B (B:)
    gepfligvsggtasgkssvcakivqllgqnevqkqvvilsqdsfyrvltseqkakalkgq
    fnfdhpdafdnelilktlkeitegktvqipvydfvshsrkeetvtvypadvvlfegilaf
    ysqevrdlfqmklfvdtdadtrlsrrvlrdisergrdleqilsqyitfvkpafeefclpt
    kkyadviiprgadnlvainlivqhiqdilng