PDB entry 6n1t

View 6n1t on RCSB PDB site
Description: toxoplasma gondii ts-dhfr in complex with selective inhibitor 3
Deposited on 2018-11-11, released 2019-01-23
The last revision was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional dihydrofolate reductase-thymidylate synthase
    Species: Toxoplasma gondii [TaxId:5811]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Bifunctional dihydrofolate reductase-thymidylate synthase
    Species: Toxoplasma gondii [TaxId:5811]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BOD, UMP, NDP, CB3

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6n1tA (A:)
mqkpvclvvamtpkrgiginnglpwphlttdfkhfsrvtkttpeeasrfnavvmgrktwe
smprkfrplvdrlnivvssslkeediaaekpqaegqqrvrvcaslpaalslleeeykdsv
dqifvvggaglyeaalslgvashlyitrvarefpcdvffpafpgddilsnkstaaekdne
atyrpifisktfsdngvpydfvvlekrrktddaataepsnamssltstrettpvhglqap
ssaaaiapvlawmdeedrkkreqkeliravphvhfrgheefqyldliadiinngrtmddr
tgvgviskfgctmrysldqafpllttkrvfwkgvleellwfirgdtnanhlsekgvkiwd
knvtrefldsrnlphrevgdigpgygfqwrhfgaaykdmhtdytgqgvdqlknviqmlrt
nptdrrmlmtawnpaaldemalppchllcqfyvndqkelscimyqrscdvglgvpfnias
yslltlmvahvcnlkpkefihfmgnthvytnhvealkeqlrreprpfpivnilnkerike
iddftaedfevvgyvphgriqmemav

    Sequence, based on observed residues (ATOM records):
    >6n1tA (A:)
kpvclvvamtpkrgiginnglpwphlttdfkhfsrvtkttpasrfnavvmgrktwesmpr
kfrplvdrlnivvssslkeediaaekpqaegqqrvrvcaslpaalslleeeykdsvdqif
vvggaglyeaalslgvashlyitrvarefpcdvffpafpgddilsnkatyrpifisktfs
dngvpydfvvlekrrssaaaiapvlawmdeliravphvhfrgheefqyldliadiinngr
tmddrtgvgviskfgctmrysldqafpllttkrvfwkgvleellwfirgdtnanhlsekg
vkiwdknvtrefldsrnlphrevgdigpgygfqwrhfgaaykdmhtdytgqgvdqlknvi
qmlrtnptdrrmlmtawnpaaldemalppchllcqfyvndqkelscimyqrscdvglgvp
fniasyslltlmvahvcnlkpkefihfmgnthvytnhvealkeqlrreprpfpivnilnk
erikeiddftaedfevvgyvphgriqmemav

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6n1tB (B:)
mqkpvclvvamtpkrgiginnglpwphlttdfkhfsrvtkttpeeasrfnavvmgrktwe
smprkfrplvdrlnivvssslkeediaaekpqaegqqrvrvcaslpaalslleeeykdsv
dqifvvggaglyeaalslgvashlyitrvarefpcdvffpafpgddilsnkstaaekdne
atyrpifisktfsdngvpydfvvlekrrktddaataepsnamssltstrettpvhglqap
ssaaaiapvlawmdeedrkkreqkeliravphvhfrgheefqyldliadiinngrtmddr
tgvgviskfgctmrysldqafpllttkrvfwkgvleellwfirgdtnanhlsekgvkiwd
knvtrefldsrnlphrevgdigpgygfqwrhfgaaykdmhtdytgqgvdqlknviqmlrt
nptdrrmlmtawnpaaldemalppchllcqfyvndqkelscimyqrscdvglgvpfnias
yslltlmvahvcnlkpkefihfmgnthvytnhvealkeqlrreprpfpivnilnkerike
iddftaedfevvgyvphgriqmemav

    Sequence, based on observed residues (ATOM records):
    >6n1tB (B:)
pvclvvamtpkrgiginnglpwphlttdfkhfsrvtkttpasrfnavvmgrktwesmprk
frplvdrlnivvssslkeediaaekpqaegqqrvrvcaslpaalslleeeykdsvdqifv
vggaglyeaalslgvashlyitrvarefpcdvffpafpgddilsnkatyrpifisktfsd
ngvpydfvvlekrrssaaaiapvlawmdeeliravphvhfrgheefqyldliadiinngr
tmddrtgvgviskfgctmrysldqafpllttkrvfwkgvleellwfirgdtnanhlsekg
vkiwdknvtrefldsrnlphrevgdigpgygfqwrhfgaaykdmhtdytgqgvdqlknvi
qmlrtnptdrrmlmtawnpaaldemalppchllcqfyvndqkelscimyqrscdvglgvp
fniasyslltlmvahvcnlkpkefihfmgnthvytnhvealkeqlrreprpfpivnilnk
erikeiddftaedfevvgyvphgriqmemav