PDB entry 6n13

View 6n13 on RCSB PDB site
Description: UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin
Class: ligase
Keywords: E3 enzyme, protein degradation, mitochondrial protein, LIGASE
Deposited on 2018-11-08, released 2018-11-28
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: NMR
Resolution: N/A
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: phosphoubiquitin
  Species: Homo sapiens [TaxId:9606]
  Gene: UBC
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0CG48 (0-75)
  Domains in SCOPe 2.08: d6n13a_
• Chain 'B':
  Compound: E3 ubiquitin-protein ligase parkin
  Species: Homo sapiens [TaxId:9606]
  Gene: PRKN, PARK2
  Database cross-references and differences (RAF-indexed):
  • Uniprot O60260 (0-321)
    • engineered mutation (203)
• Chain 'C':
  Compound: Ubiquitin-conjugating enzyme E2 L3
  Species: Homo sapiens [TaxId:9606]
  Gene: UBE2L3, UBCE7, UBCH7
  Database cross-references and differences (RAF-indexed):
  • Uniprot P68036 (2-155)
    • engineered mutation (18)
    • engineered mutation (87)
    • engineered mutation (138)
  Domains in SCOPe 2.08: d6n13c_
• Chain 'D':
  Compound: Ubiquitin
  Species: Homo sapiens [TaxId:9606]
  Gene: UBB
  Database cross-references and differences (RAF-indexed):
  • Uniprot P0CG47 (0-75)
  Domains in SCOPe 2.08: d6n13d_
• Heterogens: ZN

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6n13A (A:)
  mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
  iqkestlhlvlrlrgg
  

  
  
• Chain 'B':
  No sequence available.
  
  
• Chain 'C':
  Sequence, based on SEQRES records: (download)
  

  >6n13C (C:)
  ghmaasrrlmkeleeirksgmknfrniqvdeanlltwqglivpdnppydkgafrieinfp
  aeypfkppkitfktkiyhpnidekgqvklpvisaenwkpatktdqviqslialvndpqpe
  hplradlaeeyskdrkkfsknaeeftkkygekrpvd
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6n13C (C:)
  maasrrlmkeleeirksgmknfrniqvdeanlltwqglivpdnppydkgafrieinfpae
  ypfkppkitfktkiyhpnidekgqvklpvisaenwkpatktdqviqslialvndpqpehp
  lradlaeeyskdrkkfsknaeeftkkygekrpvd
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6n13D (D:)
  mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
  iqkestlhlvlrlrgg