PDB entry 6mzc

View 6mzc on RCSB PDB site
Description: human tfiid bc core
Deposited on 2018-11-05, released 2018-11-28
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 4.5 Å
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'B':
    Compound: transcription initiation factor tfiid subunit 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Transcription initiation factor TFIID subunit 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Transcription initiation factor TFIID subunit 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15542
    • PDB 6MZC (496-535)
    • PDB 6MZC (536-End)
  • Chain 'H':
    Compound: transcription initiation factor tfiid subunit 6
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: transcription initiation factor tfiid subunit 6
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49848
    • PDB 6MZC (206-210)
    • PDB 6MZC (211-End)
  • Chain 'K':
    Compound: Transcription initiation factor TFIID subunit 8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7Z7C8 (Start-119)
    • PDB 6MZC (120-170)
    • Uniprot Q7Z7C8 (171-End)
  • Chain 'M':
    Compound: Transcription initiation factor TFIID subunit 9
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16594 (Start-108)
    • PDB 6MZC (109-115)
    • Uniprot Q16594
  • Chain 'O':
    Compound: Transcription initiation factor TFIID subunit 10
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: Transcription initiation factor TFIID subunit 12
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Z':
    Compound: Poly(UNK)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MZC (0-237)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mzcB (B:)
mpltgveparmnrkkgdkgfesprpyklthqvvcinninfqrksvvgfveltifptvanl
nriklnskqcriyrvrindleaafiyndptlevchseskqrnlnyfsnayaaavsavdpd
agngelcikvpselwkhvdelkvlkihinfsldqpkgglhfvvpsvegsmaergahvfsc
gyqnstrfwfpcvdsyselctwkleftvdaamvavsngdlvetvythdmrkktfhymlti
ptaasnislaigpfeilvdpymhevthfclpqllpllkhttsylhevfefyeeiltcryp
yscfktvfideayvevaayasmsifstnllhsamiidetpltrrclaqslaqqffgcfis
rmswsdewvlkgisgyiyglwmkktfgvneyrhwikeeldkivayelktggvllhpifgg
gkekdnpashlhfsikhphtlsweyysmfqckahlvmrlienrismefmlqvfnkllsla
stassqkfqshmwsqmlvstsgflksisnvsgkdiqplikqwvdqsgvvkfygsfafnrk
rnvleleikqdytspgtqkyvgplkvtvqeldgsfnhtlqieenslkhdipchsksrrnk
kkkiplmngeevdmdlsamdadspllwiridpdmsvlrkvefeqadfmwqyqlryerdvv
aqqesilalekfptpasrlaltdileqeqcfyrvrmsacfclakiansmvstwtgppamk
slftrmfcckscpnivktnnfmsfqsyflqktmpvamallrdvhnlcpkevltfildlik
yndnrknkfsdnyyraemidalansvtpavsvnnevrtldnlnpdvrlileeitrflnme
kllpsyrhtitvsclrairvlqknghvpsdpalfksyaeyghfvdiriaaleavvdytkv
drsyeelqwllnmiqndpvpyvrhkilnmltknppftknmesplcnealvdqlwklmnsg
tshdwrlrcgavdlyftlfglsrpsclplpelglvlnlkekkavlnptiipesvagnqea
annpsshpqlvgfqnpfsssqdeeeidmdtvhdsqafishhlnmlerpstpglskyrpas
srsalipqhsagcdstpttkpqwslelarkgtgkeqaplemsmhpaasaplsvftkesta
skhsdhhhhhhhehkkkkkkhkhkhkhkhkhdskekdkepftfsspasgrsirspslsd

    Sequence, based on observed residues (ATOM records):
    >6mzcB (B:)
fesprpyklthqvvcinninfqrksvvgfveltifptvanlnriklnskqcriyrvrind
leaafiyndptlevchseskqrnlnyfsnayaaavsavdpdagngelcikvpselwkhvd
elkvlkihinfsldqpkgglhfvvpsvegsmaergahvfscgyqnstrfwfpcvdsysel
ctwkleftvdaamvavsngdlvetvythdmrkktfhymltiptaasnislaigpfeilvd
pymhevthfclpqllpllkhttsylhevfefyeeiltcrypyscfktvfideayvevaay
asmsifstnllhsamiidetpltrrclaqslaqqffgcfisrmswsdewvlkgisgyiyg
lwmkktfgvneyrhwikeeldkivayelktggvllhpifgggkekdnpashlhfsikhph
tlsweyysmfqckahlvmrlienrismefmlqvfnkllslastassqkfqshmwsqmlvs
tsgflksisnvsgkdiqplikqwvdqsgvvkfygsfafnrkrnvleleikqdytspgtqk
yvgplkvtvqeldgsfnhtlqieenslkhdipchsksrrnkkkkiplmngeevdmdlsam
dadspllwiridpdmsvlrkvefeqadfmwqyqlryerdvvaqqesilalekfptpasrl
altdileqeqcfyrvrmsacfclakiansmvstwtgppamkslftrmfcckscpnivktn
nfmsfqsyflqktmpvamallrdvhnlcpkevltfildlikyndnrknkfsdnyyraemi
dalansvtpavsvnnevrtldnlnpdvrlileeitrflnmekllpsyrhtitvsclrair
vlqknghvpsdpalfksyaeyghfvdiriaaleavvdytkvdrsyeelqwllnmiqndpv
pyvrhkilnmltknppftknmesplcnealvdqlwklmnsgtshdwrlrcgavdlyftlf
glsrpscl

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6mzcE (E:)
maagsdlldevffnsevdekvvsdlvgslesqlaasaahhhhlaprtpevraaaagalgn
hvvsgspagaagagpaapaegapgaapepppagrarpggggpqrpgppsprrplvpagpa
ppaaklrpppegsagscapvpaaaavaagpepapagpakpagpaalaaragpgpgpgpgp
gpgpgpgkpagpgaaqtlngsaallnshhaaapavslvnngpaallplpkpaapgtviqt
ppfvgaaappapaapsppaapapaapaaappppppapatlarppghpagpptaapavppp
aaaqnggsagaapapapaaggpagvsgqpgpgaaaaapapgvkaespkrvvqaappaaqt
laasgpastaasmvigptmqgalpspaavpppapgtptglpkgaagavtqslsrtptatt
sgiratltptvlaprlpqppqnptniqnfqlppgmvlvrsengqllmipqqalaqmqaqa
haqpqttmaprpatptsappvqistvqapgtpiiarqvtpttiikqvsqaqttvqpsatl
qrspgvqpqlvlggaaqtaslgtatavqtgtpqrtvpgatttssaatetmenvkkcknfl
stliklassgkqstetaanvkelvqnlldgkieaedftsrlyrelnsspqpylvpflkrs
lpalrqltpdsaafiqqsqqqpppptsqattaltavvlsssvqrtagktaatvtsalqpp
vlsltqptqvgvgkqgqptplviqqppkpgalirppqvtltqtpmvalrqphnrimlttp
qqiqlnplqpvpvvkpavlpgtkalsavsaqaaaaqknklkepgggsfrddddindvasm
agvnlseesarilatnselvgtltrsckdetfllqaplqrrileigkkhgitelhpdvvs
yvshatqqrlqnlvekisetaqqknfsykdddryeqasdvraqlkffeqldqiekqrkde
qereilmraaksrsrqedpeqlrlkqkakemqqqelaqmrqrdanltalaaigprkkrkv
dcpgpgsgaegsgpgsvvpgssgvgtprqftrqritrvnlrdlifcleneretshsllly
kaflk

    Sequence, based on observed residues (ATOM records):
    >6mzcE (E:)
etfllqaplqrrileigkkhgitelhpdvvsyvshatqqrlqnlvekisetaqqknfsyk
dddryeqasdvraqlkffeqldqiekqrkdeqereilmraak

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6mzcG (G:)
maalaeeqtevavklepegpptllppqagdgagegsggttnngpnggggnvaassstggd
ggtpkptvavsaaapagaapvpaaapdagaphdrqtllavlqflrqsklreaeealrrea
glleeavagsgapgevdsagaevtsallsrvtasapgpaapdppgtgasgatvvsgsasg
paapgkvgsvavedqpdvsavlsaynqqgdptmyeeyysglkhfiecsldchraelsqlf
yplfvhmylelvynqheneaksffekfhgdqecyyqddlrvlssltkkehmkgnetmldf
rtskfvlrisrdsyqllkrhlqekqnnqiwnivqehlyidifdgmprskqqidamvgsla
geakreankskvffgllkepeievplddedeegeneegkpkkkkpkkdsigskskkqdpn
appqnriplpelkdsdkldkimnmkettkrvrlgpdclpsicfytflnayqgltavdvtd
dssliaggfadstvrvxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxkily
ghsgpvygasfspdrnyllsssedgtvrlwslqtftclvgykghnypvwdtqfspygyyf
vsgghdrvarlwatdhyqplrifaghladvnctrfhpnsnyvatgsadrtvrlwdvlngn
cvriftghkgpihsltfspngrflatgatdgrvllwdighglmvgelkghtdtvcslrfs
rdgeilasgsmdntvrlwdaikafedletddfttatghinlpensqelllgtymtkstpv
vhlhftrrnlvlaagayspq

    Sequence, based on observed residues (ATOM records):
    >6mzcG (G:)
dptmyeeyysglkhfiecsldchraelsqlfyplfvhmylelvynqheneaksffekfhg
dqecyyqddlrvlssltkkehmkgnetmldfrtskfvlrisrdsyqllkrhlqekqnnqi
wnivqehlyidifdlpsicfytflnayqgltavdvtddssliaggfadstvrvxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxkilyghsgpvygasfspdrnyllssse
dgtvrlwslqtftclvgykghnypvwdtqfspygyyfvsgghdrvarlwatdhyqplrif
aghladvnctrfhpnsnyvatgsadrtvrlwdvlngncvriftghkgpihsltfspngrf
latgatdgrvllwdighglmvgelkghtdtvcslrfsrdgeilasgsmdntvrlwdaika
fedletddfttatghinlpensqelllgtymtkstpvvhlhftrrnlvlaaga

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6mzcH (H:)
maeekklklsntvlpsesmkvvaesmgiaqiqeetcqlltdevsyrikeiaqdalkfmhm
gkrqklttsdidyalklknveplygfhaqefipfrfasgggrelyfyeekevdlsdiint
plprvpldvclkahwlsiegcqpaipenpppapkeqqkaeateplksakpgqeedgplkg
kgqgattadgkgkekkappllegaplrlkprsihelsveqqlyykeiteacvgsceakra
ealqsiatdpglyqmlprfstfisegvrvnvvqnnlalliylmrmvkalmdnptlyleky
vhelipavmtcivsrqlclrpdvdnhwalrdfaarlvaqickhfstttnniqsritktft
kswvdektpwttrygsiaglaelghdviktlilprlqqegerirsvldgpvlsnidriga
dhvqslllkhcapvlaklrpppdnqdayraefgslgpllcsqvvkaraqaalqaqqvnrt
tltitqprptltlsqapqpgprtpgllkvpgsialpvqtlvsaraaappqpsppptkfiv
msssssapstqqvlslstsapgsgstttspvtttvpsvqpivklvstattappstapsgp
gsvqkyivvslpptgegkggptshpspvpppasspsplsgsalcggkqeagdspppapgt
pkangsqpnsgspqpap

    Sequence, based on observed residues (ATOM records):
    >6mzcH (H:)
sveqqlyykeiteacvgsceakraealqsiatdpglyqmlprfstfisegvrvnvvqnnl
alliylmrmvkalmdnptlylekyvhelipavmtcivsrqlclrpdvdnhwalrdfaarl
vaqickhfstttnniqsritktftkswvdektpwttrygsiaglaelghdviktlilprl
qqegerirsvldgpvlsnidrigadhvqslllkhcapvlaklrpppdnqdayraefgslg
pllcsqvvkaraqaalq

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6mzcI (I:)
maeekklklsntvlpsesmkvvaesmgiaqiqeetcqlltdevsyrikeiaqdalkfmhm
gkrqklttsdidyalklknveplygfhaqefipfrfasgggrelyfyeekevdlsdiint
plprvpldvclkahwlsiegcqpaipenpppapkeqqkaeateplksakpgqeedgplkg
kgqgattadgkgkekkappllegaplxxxxxxxxxxsveqqlyykeiteacvgsceakra
ealqsiatdpglyqmlprfstfisegvrvnvvqnnlalliylmrmvkalmdnptlyleky
vhelipavmtcivsrqlclrpdvdnhwalrdfaarlvaqickhfstttnniqsritktft
kswvdektpwttrygsiaglaelghdviktlilprlqqegerirsvldgpvlsnidriga
dhvqslllkhcapvlaklrpppdnqdayraefgslgpllcsqvvkaraqaalqaqqvnrt
tltitqprptltlsqapqpgprtpgllkvpgsialpvqtlvsaraaappqpsppptkfiv
msssssapstqqvlslstsapgsgstttspvtttvpsvqpivklvstattappstapsgp
gsvqkyivvslpptgegkggptshpspvpppasspsplsgsalcggkqeagdspppapgt
pkangsqpnsgspqpap

    Sequence, based on observed residues (ATOM records):
    >6mzcI (I:)
klklsntvlpsesmkvvaesmgiaqiqeetcqlltdevsyrikeiaqdalkfmhmgkrqk
lttsdidyalklxxxxxxxxxxsveqqlyykeiteacvgsceakraealqsiatdpglyq
mlprfstfisegvrvnvvqnnlalliylmrmvkalmdnptlylekyvhelipavmtcivs
rqlclrpdvdnhwalrdfaarlvaqickhfstttnniqsritktftkswvdektpwttry
gsiaglaelghdviktlilprlqqegerirsvldgpvlsnidrigadhvqslllkhcapv
laklrpppdnqdayraefgslgpllcsqvvkaraqaalq

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6mzcK (K:)
madaaatagaggsgtrsgskqstnpadnyhlarrrtlqvvvssllteagfesaekasvet
ltemlqsyiseigrsaksycehtartqptlsdivvtlvemgfnvdtlpayakrsqrmvit
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxyqvlrekaa
sqrrdveraltrfmaktgetqslfkddvstfpliaarpftipyltallpselemqqmeet
dsseqdeqtdtenlalhismedsgaekentsvlqqnpslsgsrngeeniidnpylrpvkk
pkirrkksls

    Sequence, based on observed residues (ATOM records):
    >6mzcK (K:)
nyhlarrrtlqvvvssllteagfesaekasvetltemlqsyiseigrsaksycehtartq
ptlsdivvtlvemgfnvdtlpayakrsqrmvitxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxyqvlrekaasqrrdveraltrfmaktgetqslfkdd
vstfpliaarpftipyltallp

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6mzcM (M:)
mesgktaspksmpkdaqmmaqilkdmgiteyeprvinqmlefafryvttilddakiyssh
akkatvdaddvrlaiqcradqsftsppprdflldiarqrnqtplplikpxxxxxxxpdry
cltapnyrlkslqkkastsagritvprlsvgsvtsrpstptlgtptpqtmsvstkvgtpm
sltgqrftvqmptsqspavkasipatsavqnvlinpsligsknilittnmmssqntanes
snalkrkredddddddddddydnl

    Sequence, based on observed residues (ATOM records):
    >6mzcM (M:)
pkdaqmmaqilkdmgiteyeprvinqmlefafryvttilddakiysshakkatvdaddvr
laiqcradqsftsppprdflldiarqrnqtplplikpxxxxxxx

  • Chain 'O':
    Sequence, based on SEQRES records:
    >6mzcO (O:)
mscsgsgadpeaapasaasapgpappvsapaalpsstaaenkaspagtaggpgagaaagg
tgplaaragepaerrgaapvsaggaappegaisngvyvlpsaangdvkpvvsstplvdfl
mqledytptipdavtgyylnragfeasdpriirlislaaqkfisdiandalqhckmkgta
sgssrskskdrkytltmedltpalseyginvkkphyft

    Sequence, based on observed residues (ATOM records):
    >6mzcO (O:)
stplvdflmqledytptipdavtgyylnragfeasdpriirlislaaqkfisdiandalq
hckmkkytltmedltpalseyg

  • Chain 'R':
    Sequence, based on SEQRES records:
    >6mzcR (R:)
mnqfgpsalinlsnfssikpepastppqgsmanstavvkipgtpgaggrlspennqvltk
kklqdlvrevdpneqldedveemllqiaddfiesvvtaacqlarhrksstlevkdvqlhl
erqwnmwipgfgseeirpykkactteahkqrmalirkttkk

    Sequence, based on observed residues (ATOM records):
    >6mzcR (R:)
nqvltkkklqdlvrevdpneqldedveemllqiaddfiesvvtaacqlarhrksstlevk
dvqlhlerqwnmwi

  • Chain 'Z':
    Sequence; same for both SEQRES and ATOM records:
    >6mzcZ (Z:)
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