PDB entry 6my0

View 6my0 on RCSB PDB site
Description: Structure of 53BP1 Tandem Tudor domains with E1549P and D1550N mutations
Class: protein binding
Keywords: 53BP1, DNA damage response, DNA double-strand breaks, Tudor domain, Protein binding
Deposited on 2018-10-31, released 2019-11-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-11-27, with a file datestamp of 2019-11-22.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: TP53-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TP53BP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12888 (3-122)
      • expression tag (1-2)
      • engineered mutation (68-69)
    Domains in SCOPe 2.08: d6my0a1, d6my0a2, d6my0a3
  • Chain 'B':
    Compound: TP53-binding protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: TP53BP1
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q12888
      • engineered mutation (68-69)
    Domains in SCOPe 2.08: d6my0b1, d6my0b2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6my0A (A:)
ghmnsfvglrvvakwssngyfysgkitrdvgagkykllfddgyecdvlgkdillcdpipl
dtevtalspneyfsagvvkghrkesgelyysiekegqrkwykrmavilsleqgnrlreqy
glg

    Sequence, based on observed residues (ATOM records): (download) 
    >6my0A (A:)
hmnsfvglrvvakwssngyfysgkitrdvgagkykllfddgyecdvlgkdillcdpipld
tevtalspneyfsagvvkghrkesgelyysiekegqrkwykrmavilsleqgnrlreqyg
lg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6my0B (B:)
ghmnsfvglrvvakwssngyfysgkitrdvgagkykllfddgyecdvlgkdillcdpipl
dtevtalspneyfsagvvkghrkesgelyysiekegqrkwykrmavilsleqgnrlreqy
glg

    Sequence, based on observed residues (ATOM records): (download) 
    >6my0B (B:)
sfvglrvvakwssngyfysgkitrdvgagkykllfddgyecdvlgkdillcdpipldtev
talspneyfsagvvkghrkesgelyysiekegqrkwykrmavilsleqgnrlreqygl