PDB entry 6mwx

View 6mwx on RCSB PDB site
Description: cryoem structure of chimeric eastern equine encephalitis virus with fab of eeev-69 antibody
Deposited on 2018-10-30, released 2018-12-19
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: EM
Resolution: 8.2 Å
R-factor: N/A
AEROSPACI score: -0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: e1
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: e2
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: EEEV-69 antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MWX
  • Chain 'D':
    Compound: EEEV-69 antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: e1
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: e2
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: EEEV-69 antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MWX
  • Chain 'H':
    Compound: EEEV-69 antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: e1
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: e2
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: EEEV-69 antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MWX
  • Chain 'L':
    Compound: EEEV-69 antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: e1
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: e2
    Species: Eastern equine encephalitis virus [TaxId:11021]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: EEEV-69 antibody heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MWX (0-217)
  • Chain 'P':
    Compound: EEEV-69 antibody light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MWX (0-96)
    • Uniprot G0YP42 (97-End)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6mwxA (A:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesftsaisatawswlkvlvggtsa
fivlgliatavvalvlffhrh

    Sequence, based on observed residues (ATOM records):
    >6mwxA (A:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesft

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mwxB (B:)
dldthftqyklarpyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgv
dlaymsfmngktqksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrh
tctvahkvefrpvgrekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsi
hsakvkitvpsgaqvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrl
prgegdtfkgklhvpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsd
anptrqwierpttvnftvtgegleytwgnhppkrvwaqesgegnphgwphevvvyyynry
plttiiglctcvaiimvscvtsvwllcrtrnlcitpyklapnaqvpillallccikptra

    Sequence, based on observed residues (ATOM records):
    >6mwxB (B:)
pyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgvdlaymsfmngktq
ksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrhtctvahkvefrpv
grekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsihsakvkitvpsga
qvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrlprgegdtfkgklh
vpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsdanptrqwierptt
vnftvtgegleytwgnhppkrvwaq

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6mwxC (C:)
qiqlvqsgrevknpgetvkisckasgytfteypmlwvkqapgkgfrwmgliytntgepty
aeefkgrfvfsleisastaylqinnltnedtatyfcvrdyfisldywgqgttltvssakt
tapsvyplapvcggttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpallqsglyt
lsssvtvtsntwpsqtitcnvahpasstkvdkkiesrr

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6mwxD (D:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsradc

    Sequence, based on observed residues (ATOM records):
    >6mwxD (D:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsr

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6mwxE (E:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesftsaisatawswlkvlvggtsa
fivlgliatavvalvlffhrh

    Sequence, based on observed residues (ATOM records):
    >6mwxE (E:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesft

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6mwxF (F:)
dldthftqyklarpyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgv
dlaymsfmngktqksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrh
tctvahkvefrpvgrekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsi
hsakvkitvpsgaqvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrl
prgegdtfkgklhvpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsd
anptrqwierpttvnftvtgegleytwgnhppkrvwaqesgegnphgwphevvvyyynry
plttiiglctcvaiimvscvtsvwllcrtrnlcitpyklapnaqvpillallccikptra

    Sequence, based on observed residues (ATOM records):
    >6mwxF (F:)
pyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgvdlaymsfmngktq
ksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrhtctvahkvefrpv
grekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsihsakvkitvpsga
qvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrlprgegdtfkgklh
vpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsdanptrqwierptt
vnftvtgegleytwgnhppkrvwaq

  • Chain 'G':
    Sequence; same for both SEQRES and ATOM records:
    >6mwxG (G:)
qiqlvqsgrevknpgetvkisckasgytfteypmlwvkqapgkgfrwmgliytntgepty
aeefkgrfvfsleisastaylqinnltnedtatyfcvrdyfisldywgqgttltvssakt
tapsvyplapvcggttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpallqsglyt
lsssvtvtsntwpsqtitcnvahpasstkvdkkiesrr

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6mwxH (H:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsradc

    Sequence, based on observed residues (ATOM records):
    >6mwxH (H:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsr

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6mwxI (I:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesftsaisatawswlkvlvggtsa
fivlgliatavvalvlffhrh

    Sequence, based on observed residues (ATOM records):
    >6mwxI (I:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesft

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6mwxJ (J:)
dldthftqyklarpyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgv
dlaymsfmngktqksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrh
tctvahkvefrpvgrekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsi
hsakvkitvpsgaqvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrl
prgegdtfkgklhvpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsd
anptrqwierpttvnftvtgegleytwgnhppkrvwaqesgegnphgwphevvvyyynry
plttiiglctcvaiimvscvtsvwllcrtrnlcitpyklapnaqvpillallccikptra

    Sequence, based on observed residues (ATOM records):
    >6mwxJ (J:)
pyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgvdlaymsfmngktq
ksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrhtctvahkvefrpv
grekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsihsakvkitvpsga
qvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrlprgegdtfkgklh
vpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsdanptrqwierptt
vnftvtgegleytwgnhppkrvwaq

  • Chain 'K':
    Sequence; same for both SEQRES and ATOM records:
    >6mwxK (K:)
qiqlvqsgrevknpgetvkisckasgytfteypmlwvkqapgkgfrwmgliytntgepty
aeefkgrfvfsleisastaylqinnltnedtatyfcvrdyfisldywgqgttltvssakt
tapsvyplapvcggttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpallqsglyt
lsssvtvtsntwpsqtitcnvahpasstkvdkkiesrr

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6mwxL (L:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsradc

    Sequence, based on observed residues (ATOM records):
    >6mwxL (L:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsr

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6mwxM (M:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesftsaisatawswlkvlvggtsa
fivlgliatavvalvlffhrh

    Sequence, based on observed residues (ATOM records):
    >6mwxM (M:)
yehtavmpnkvgipykalverpgyapvhlqiqlvntriipstnleyitckyktkvpspvv
kccgatqctskphpdyqcqvftgvypfmwggaycfcdtentqmseayverseecsidhak
aykvhtgtvqamvnitygsvswrsadvyvngetpakigdakliigplssawspfdnkvvv
yghevynydfpeygtgkagsfgdlqsrtstsndlyantnlklqrpqagivhtpftqapsg
ferwkrdkgaplndvapfgcsialeplraencavgsipisidipdaaftrisetptvsdl
eckitectyasdfggiatvayksskagncpihspsgvavikendvtlaesgsftfhfsta
nihpafklqvctsavtckgdckppkdhivdypaqhtesft

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6mwxN (N:)
dldthftqyklarpyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgv
dlaymsfmngktqksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrh
tctvahkvefrpvgrekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsi
hsakvkitvpsgaqvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrl
prgegdtfkgklhvpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsd
anptrqwierpttvnftvtgegleytwgnhppkrvwaqesgegnphgwphevvvyyynry
plttiiglctcvaiimvscvtsvwllcrtrnlcitpyklapnaqvpillallccikptra

    Sequence, based on observed residues (ATOM records):
    >6mwxN (N:)
pyiadcpncghsrcdspiaieevrgdahagviriqtsamfglktdgvdlaymsfmngktq
ksikidnlhvrtsapcslvshhgyyilaqcppgdtvtvgfhdgpnrhtctvahkvefrpv
grekyrhppehgvelpcnrythkradqghyvemhqpglvadhsllsihsakvkitvpsga
qvkyyckcpdvregitssdhtttctdvkqcraylidnkkwvynsgrlprgegdtfkgklh
vpfvpvkakciatlapeplvehkhrtlilhlhpdhptllttrslgsdanptrqwierptt
vnftvtgegleytwgnhppkrvwaq

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records:
    >6mwxO (O:)
qiqlvqsgrevknpgetvkisckasgytfteypmlwvkqapgkgfrwmgliytntgepty
aeefkgrfvfsleisastaylqinnltnedtatyfcvrdyfisldywgqgttltvssakt
tapsvyplapvcggttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpallqsglyt
lsssvtvtsntwpsqtitcnvahpasstkvdkkiesrr

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6mwxP (P:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsradc

    Sequence, based on observed residues (ATOM records):
    >6mwxP (P:)
qavvtqesalttspgetvtltcrsnigavtssncanwvqekpdhfftgligdtnnrrsgv
parfsgsligdkaaltitgaqtedeaiyfcalwynnlwvfgggtkltvlgqpksspsvtl
fppsseeletnkatlvctitdfypgvvtvdwkvdgtpvtqgmettqpskqsnnkymassy
ltltarawerhssyscqvtheghtvekslsr