PDB entry 6mw7

View 6mw7 on RCSB PDB site
Description: crystal structure of atpase module of smchd1 bound to atp
Deposited on 2018-10-29, released 2019-09-11
The last revision was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Structural maintenance of chromosomes flexible hinge domain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: SMCHD1, KIAA0650
    Database cross-references and differences (RAF-indexed):
    • Uniprot A6NHR9
      • engineered mutation (128)
  • Chain 'B':
    Compound: Structural maintenance of chromosomes flexible hinge domain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: SMCHD1, KIAA0650
    Database cross-references and differences (RAF-indexed):
    • Uniprot A6NHR9
      • engineered mutation (128)
  • Chain 'C':
    Compound: Structural maintenance of chromosomes flexible hinge domain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: SMCHD1, KIAA0650
    Database cross-references and differences (RAF-indexed):
    • Uniprot A6NHR9
      • engineered mutation (128)
  • Chain 'D':
    Compound: Structural maintenance of chromosomes flexible hinge domain-containing protein 1
    Species: Homo sapiens [TaxId:9606]
    Gene: SMCHD1, KIAA0650
    Database cross-references and differences (RAF-indexed):
    • Uniprot A6NHR9
      • engineered mutation (128)
  • Heterogens: ATP, MG, SO4, NA, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6mw7A (A:)
gsaaaghrtvylfdrrekeselgdrplqvgersdyagfracvcqtlgispeekfvittts
rkeitcdnfdetvkdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegq
nplpfalaalidnslsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwa
vyrlskftrqgdfesdhsgyvrpvpvprslnsdisyfgvggkqavffvgqsarmiskpad
sqdvhelvlskedfekkeknkeaiysgyirnrkpsdsvhitndderflhhliieekekds
ftavvitgvqpehiqylknyfhlwtrqlahiyhyyihgpkgneirtskevepfnnidiei
smfekgkvpkivnlreiqddmqtlyvntaadsfefkahvegdgvvegiiryhpflydret
ypddpcfpsklkdeddeddcfilekaargkrpifecfwngrlipytsvedfdwctppkkr
glapiecynrisgalftndkfqvstnkltfmdlelklkdkntlftrilngqeqrmkidre
falwlkdchekydkqikftlfk

    Sequence, based on observed residues (ATOM records):
    >6mw7A (A:)
hrtvylfdrrekeselgdrplqvgersdyagfracvcqtlgispeekfvitttsrkeitc
dnfdetvkdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegqnplpfa
laalidnslsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwavyrlsk
ftryvrpvpvprslnsdisyfgvggkqavffvgqsarmiskpadsqdvhelvlskedfek
keknkeaiysgyirnrkpsdsvhitndderflhhliieekekdsftavvitgvqpehiqy
lknyfhlwtrqlahiyhyyihgpkgneinidieismfekgkvpkivnlreiqddmqtlyv
ntaadsfefkahvegdgvvegiiryhpflydretypddpcfpaargkrpifecfwngrli
pytsvedfdwctppglapiecynrisgalftndkfqvstnkltfmdlelklkdkntlftr
ilngqeqrmkidrefalwlkdchekydkqikftl

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mw7B (B:)
gsaaaghrtvylfdrrekeselgdrplqvgersdyagfracvcqtlgispeekfvittts
rkeitcdnfdetvkdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegq
nplpfalaalidnslsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwa
vyrlskftrqgdfesdhsgyvrpvpvprslnsdisyfgvggkqavffvgqsarmiskpad
sqdvhelvlskedfekkeknkeaiysgyirnrkpsdsvhitndderflhhliieekekds
ftavvitgvqpehiqylknyfhlwtrqlahiyhyyihgpkgneirtskevepfnnidiei
smfekgkvpkivnlreiqddmqtlyvntaadsfefkahvegdgvvegiiryhpflydret
ypddpcfpsklkdeddeddcfilekaargkrpifecfwngrlipytsvedfdwctppkkr
glapiecynrisgalftndkfqvstnkltfmdlelklkdkntlftrilngqeqrmkidre
falwlkdchekydkqikftlfk

    Sequence, based on observed residues (ATOM records):
    >6mw7B (B:)
rtvylfdrrekeselgdrplqvgersdyagfracvcqtlgfvitttsrkeitcdnfdetv
kdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegqnplpfalaalidn
slsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwavyrlskftrrpvp
vprslnsdisyfgvggkqavffvgqsarmiskpadsqdvhelvlskedfekkeknkeaiy
sgyirnrkpsdsvhitndderflhhliieekekdsftavvitgvqpehiqylknyfhlwt
rqlahiyhyyihgpkgnennidieismfekgkvpkivnlreiqddmqtlyvntaadsfef
kahvegdgvvegiiryhpflydretypddpcfpkaargkrpifecfwngrlipytsvedf
dwctppglapiecynrisgalftndkfqvstnkltfmdlelklkdkntlftrilngqeqr
mkidrefalwlkdchekydkqi

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6mw7C (C:)
gsaaaghrtvylfdrrekeselgdrplqvgersdyagfracvcqtlgispeekfvittts
rkeitcdnfdetvkdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegq
nplpfalaalidnslsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwa
vyrlskftrqgdfesdhsgyvrpvpvprslnsdisyfgvggkqavffvgqsarmiskpad
sqdvhelvlskedfekkeknkeaiysgyirnrkpsdsvhitndderflhhliieekekds
ftavvitgvqpehiqylknyfhlwtrqlahiyhyyihgpkgneirtskevepfnnidiei
smfekgkvpkivnlreiqddmqtlyvntaadsfefkahvegdgvvegiiryhpflydret
ypddpcfpsklkdeddeddcfilekaargkrpifecfwngrlipytsvedfdwctppkkr
glapiecynrisgalftndkfqvstnkltfmdlelklkdkntlftrilngqeqrmkidre
falwlkdchekydkqikftlfk

    Sequence, based on observed residues (ATOM records):
    >6mw7C (C:)
hrtvylfdrrekeselgdrplqvgersdyagfracvcqtlgispeekfvitttsrkeitc
dnfdetvkdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegqnplpfa
laalidnslsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwavyrlsk
ftrqgdfhsgyvrpvpvprslnsdisyfgvggkqavffvgqsarmiskpadsqdvhelvl
skedfekkeknkeaiysgyirnrkpsdsvhitndderflhhliieekekdsftavvitgv
qpehiqylknyfhlwtrqlahiyhyyihgpkgneinnidieismfekgkvpkivnlreiq
ddmqtlyvntaadsfefkahvegdgvvegiiryhpflydretypddpcfaargkrpifec
fwngrlipytsvedfdwctpplapiecynrisgalftndkfqvstnkltfmdlelklkdk
ntlftrilngqeqrmkidrefalwlkdchekydkqikft

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6mw7D (D:)
gsaaaghrtvylfdrrekeselgdrplqvgersdyagfracvcqtlgispeekfvittts
rkeitcdnfdetvkdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegq
nplpfalaalidnslsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwa
vyrlskftrqgdfesdhsgyvrpvpvprslnsdisyfgvggkqavffvgqsarmiskpad
sqdvhelvlskedfekkeknkeaiysgyirnrkpsdsvhitndderflhhliieekekds
ftavvitgvqpehiqylknyfhlwtrqlahiyhyyihgpkgneirtskevepfnnidiei
smfekgkvpkivnlreiqddmqtlyvntaadsfefkahvegdgvvegiiryhpflydret
ypddpcfpsklkdeddeddcfilekaargkrpifecfwngrlipytsvedfdwctppkkr
glapiecynrisgalftndkfqvstnkltfmdlelklkdkntlftrilngqeqrmkidre
falwlkdchekydkqikftlfk

    Sequence, based on observed residues (ATOM records):
    >6mw7D (D:)
rtvylfdrrekeselgdrplqvgersdyagfracvcqtlgispeekfvitttsrkeitcd
nfdetvkdgvtlyllqsvnqllltatkeridflphydtlvksgmyeyyasegqnplpfal
aalidnslsatsrnigvrriqikllfdetqgkpavavidngrgmtskqlnnwavyrlskf
trrpvpvprslnsdisyfgvggkqavffvgqsarmiskpadsqdvhelvlskedfekkek
nkeaiysgyirnrkpsdsvhitndderflhhliieekekdsftavvitgvqpehiqylkn
yfhlwtrqlahiyhyyihgpkgnennidieismfekgkvpkivnlreiqddmqtlyvnta
adsfefkahvegdgvvegiiryhpflydretypddpcfpkaargkrpifecfwngrlipy
tsvedfdwctpplapiecynrisgalftndkfqvstnkltfmdlelklkdkntlftriln
gqeqrmkidrefalwlkdchekydk