PDB entry 6mvx

View 6mvx on RCSB PDB site
Description: navab voltage-gated sodium channel, i217c, in complex with class 1c anti-arrhythmic flecainide
Deposited on 2018-10-28, released 2018-12-05
The last revision was dated 2019-01-02, with a file datestamp of 2018-12-28.
Experiment type: XRAY
Resolution: 3.46 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ion transport protein
    Species: Arcobacter butzleri (strain RM4018) [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5
      • engineered mutation (234)
  • Chain 'B':
    Compound: Ion transport protein
    Species: Arcobacter butzleri (strain RM4018) [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5
      • engineered mutation (234)
  • Chain 'C':
    Compound: Ion transport protein
    Species: Arcobacter butzleri (strain RM4018) [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5
      • engineered mutation (234)
  • Chain 'D':
    Compound: Ion transport protein
    Species: Arcobacter butzleri (strain RM4018) [TaxId:367737]
    Gene: Abu_1752
    Database cross-references and differences (RAF-indexed):
    • Uniprot A8EVM5
      • engineered mutation (234)
  • Heterogens: K4D, PO4

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6mvxA (A:)
mdykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfg
vyttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlr
vlrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgt
lgesfytlfqvmtleswsmgivrplmevypyawvffipfifvvtfvminlvvaicvdama
ilnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records):
    >6mvxA (A:)
lritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftieiil
riyvhrisffkdpwslfdffvvaislvpeilrvlrvlrlfrlvtavpqmrkivsalisvi
pgmlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtleswsmgivrpl
mevypyawvffipfifvvtfvminlvvaicvda

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mvxB (B:)
mdykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfg
vyttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlr
vlrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgt
lgesfytlfqvmtleswsmgivrplmevypyawvffipfifvvtfvminlvvaicvdama
ilnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records):
    >6mvxB (B:)
ylritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftieii
lriyvhrisffkdpwslfdffvvaislvpeilrvlrvlrlfrlvtavpqmrkivsalisv
ipgmlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtleswsmgivrp
lmevypyawvffipfifvvtfvminlvvaic

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6mvxC (C:)
mdykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfg
vyttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlr
vlrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgt
lgesfytlfqvmtleswsmgivrplmevypyawvffipfifvvtfvminlvvaicvdama
ilnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records):
    >6mvxC (C:)
ylritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftieii
lriyvhrisffkdpwslfdffvvaislvpfeilrvlrvlrlfrlvtavpqmrkivsalis
vipgmlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtleswsmgivr
plmevypyawvffipfifvvtfvminlvvaicvd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6mvxD (D:)
mdykddddkgslvprgshmylritnivessfftkfiiylivlngitmgletsktfmqsfg
vyttlfnqivitiftieiilriyvhrisffkdpwslfdffvvaislvptssgfeilrvlr
vlrlfrlvtavpqmrkivsalisvipgmlsvialmtlffyifaimatqlfgerfpewfgt
lgesfytlfqvmtleswsmgivrplmevypyawvffipfifvvtfvminlvvaicvdama
ilnqkeeqhiidevqshedninneiiklreeivelkeliktslkn

    Sequence, based on observed residues (ATOM records):
    >6mvxD (D:)
ylritnivessfftkfiiylivlngitmgletsktfmqsfgvyttlfnqivitiftieii
lriyvhrisffkdpwslfdffvvaislvprvlrvlrlfrlvtavpqmrkivsalisvipg
mlsvialmtlffyifaimatqlfgerfpewfgtlgesfytlfqvmtleswsmgivrplme
vypyawvffipfifvvtfvminlvvaicv