PDB entry 6mvp

View 6mvp on RCSB PDB site
Description: HCV NS5B 1b N316 bound to Compound 18
Class: viral protein
Keywords: Hepatitus C, NS5B, VIRAL PROTEIN
Deposited on 2018-10-26, released 2019-09-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-04, with a file datestamp of 2019-08-30.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Genome polyprotein
    Species: Hepatitis C virus genotype 1b (isolate BK) [TaxId:11105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26663 (2-End)
      • conflict (48)
      • conflict (102)
      • conflict (115)
      • conflict (330)
    Domains in SCOPe 2.08: d6mvpa_
  • Chain 'B':
    Compound: Genome polyprotein
    Species: Hepatitis C virus genotype 1b (isolate BK) [TaxId:11105]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P26663 (2-End)
      • conflict (48)
      • conflict (102)
      • conflict (115)
      • conflict (330)
    Domains in SCOPe 2.08: d6mvpb_
  • Heterogens: K4S, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6mvpA (A:)
masmsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsagqrqkkvtfdrlq
vlddhyrdvlkemkakastvkakllsveeackltpphsakskygygakdvrnlssravnh
ihsvwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydv
vstlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirvees
iyqccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylk
asaacraaklqdctmlvngddlvvicesagvqedaaslrvfteamtrysappgdppqpey
dlelitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyapt
lwarmilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsys
pgeinrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltp
ipaasrldlsgwfvagysggdiyhslsrarprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6mvpA (A:)
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsagqrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskygygakdvrnlssravnhih
svwkdlledtvtpidttimaknevfcvqprkparlivfpdlgvrvcekmalydvvstlpq
vvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccd
lapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacr
aaklqdctmlvngddlvvicesagvqedaaslrvfteamtrysappgdppqpeydlelit
scssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmi
lmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinr
vasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipvagy
sggdiyhs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6mvpB (B:)
masmsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsagqrqkkvtfdrlq
vlddhyrdvlkemkakastvkakllsveeackltpphsakskygygakdvrnlssravnh
ihsvwkdlledtvtpidttimaknevfcvqpekggrkparlivfpdlgvrvcekmalydv
vstlpqvvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirvees
iyqccdlapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylk
asaacraaklqdctmlvngddlvvicesagvqedaaslrvfteamtrysappgdppqpey
dlelitscssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyapt
lwarmilmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsys
pgeinrvasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltp
ipaasrldlsgwfvagysggdiyhslsrarprlehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6mvpB (B:)
smsytwtgalitpcaaeesklpinalsnsllrhhnmvyattsrsagqrqkkvtfdrlqvl
ddhyrdvlkemkakastvkakllsveeackltpphsakskygygakdvrnlssravnhih
svwkdlledtvtpidttimaknevfcvqprkparlivfpdlgvrvcekmalydvvstlpq
vvmgssygfqyspgqrveflvntwkskknpmgfsydtrcfdstvtendirveesiyqccd
lapearqaikslterlyiggpltnskgqncgyrrcrasgvlttscgntltcylkasaacr
aaklqdctmlvngddlvvicesagvqedaaslrvfteamtrysappgdppqpeydlelit
scssnvsvahdasgkrvyyltrdpttplaraawetarhtpvnswlgniimyaptlwarmi
lmthffsillaqeqlekaldcqiygacysiepldlpqiierlhglsafslhsyspgeinr
vasclrklgvpplrvwrhrarsvrarllsqggraatcgkylfnwavktklkltpipwfva
gysggdiyhs