PDB entry 6mty

View 6mty on RCSB PDB site
Description: Crystal structure of a human anti-ZIKV-DENV neutralizing antibody MZ4 isolated following ZPIV vaccination
Class: immune system
Keywords: ZIKV-DENV, Antibody, human, Vaccination, ANTIVIRAL PROTEIN, IMMUNE SYSTEM
Deposited on 2018-10-22, released 2019-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-01-06, with a file datestamp of 2021-01-01.
Experiment type: XRAY
Resolution: 2.95 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: MZ4 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IGHV4-59*08
    Database cross-references and differences (RAF-indexed):
    • PDB 6MTY (0-End)
    Domains in SCOPe 2.08: d6mtyh_
  • Chain 'L':
    Compound: MZ4 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IGLV1-44*01
    Database cross-references and differences (RAF-indexed):
    • PDB 6MTY (0-End)
    Domains in SCOPe 2.08: d6mtyl1, d6mtyl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6mtyH (H:)
qvhlqesgpglvrpsetlsltctvsdgsissyywswirqppgkglewigsiyytgstnyn
pslksrvtmsvdtsknqfslrlnsvtaadtamyycagldryswneggdhwgqgilvsvss
astkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqss
glyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepkscdk

    Sequence, based on observed residues (ATOM records): (download) 
    >6mtyH (H:)
qvhlqesgpglvrpsetlsltctvsdgsissyywswirqppgkglewigsiyytgstnyn
pslksrvtmsvdtsknqfslrlnsvtaadtamyycagldryswneggdhwgqgilvsvss
astkgpsvfplapssksttaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgly
slssvvtvpssslgtqtyicnvnhkpsntkvdkkvep

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6mtyL (L:)
qpvltqppsasgtpgqrvsiscsgsrsnlgkntvnwyqqlpgtapklliynhsrrpsgvp
erfsgsksgtsaslaisglqsedeadyfcaawddslnglyvfgtgtkvtvlrqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptec

    Sequence, based on observed residues (ATOM records): (download) 
    >6mtyL (L:)
qpvltqppsasgtpgqrvsiscsgsrsnlgkntvnwyqqlpgtapklliynhsrrpsgvp
erfsgsksgtsaslaisglqsedeadyfcaawddslnglyvfgtgtkvtvlrqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvapt