PDB entry 6mtg

View 6mtg on RCSB PDB site
Description: A Single Reactive Noncanonical Amino Acid is Able to Dramatically Stabilize Protein Structure
Class: transferase
Keywords: noncanonical amino acid, isothiocyanate, crosslink, thiourea, stabilization, TRANSFERASE
Deposited on 2018-10-19, released 2019-06-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Homoserine O-succinyltransferase
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: metAS, metA, b4013, JW3973
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07623 (Start-295)
      • engineered mutation (256)
      • expression tag (296)
    Domains in SCOPe 2.08: d6mtga1, d6mtga2
  • Chain 'B':
    Compound: Homoserine O-succinyltransferase
    Species: Escherichia coli (strain K12) [TaxId:83333]
    Gene: metAS, metA, b4013, JW3973
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07623 (Start-295)
      • engineered mutation (256)
    Domains in SCOPe 2.08: d6mtgb_
  • Heterogens: PEG, FMT, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6mtgA (A:)
mpirvpdelpavnflreenvfvmttsrasgqeirplkvlilnlmpkkietenqflrllsn
splqvdiqllridsresrntpaehlnnfycnfediqdqnfdglivtgaplglvefndvay
wpqikqvlewskdhvtstlfvcwavqaalnilygipkqtrteklsgvyehhilhphallt
rgfddsflaphsryadfpaalirdytdleilaeteegdaylfaskdkriafvtghpeyda
qtlaqeffrdveagldidvpynyfphndpqntpraswrshgnllftnwlnyyvyqihhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >6mtgA (A:)
pirvpdelpavnflreenvfvmttsraqeirplkvlilnlmpkkietenqflrllsnspl
qvdiqllridsretpaehlnnfycnfediqdqnfdglivtgaplglvefndvaywpqikq
vlewskdhvtstlfvcwavqaalnilygipkqtrteklsgvyehhilhphalltrgfdds
flaphsryadfpaalirdytdleilaeteegdaylfaskdkriafvtghpeydaqtlaqe
ffrdveagldidvpynyfphndpqntpraswrshgnllftnwlnyyvyqih

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6mtgB (B:)
mpirvpdelpavnflreenvfvmttsrasgqeirplkvlilnlmpkkietenqflrllsn
splqvdiqllridsresrntpaehlnnfycnfediqdqnfdglivtgaplglvefndvay
wpqikqvlewskdhvtstlfvcwavqaalnilygipkqtrteklsgvyehhilhphallt
rgfddsflaphsryadfpaalirdytdleilaeteegdaylfaskdkriafvtghpeyda
qtlaqeffrdveagldidvpynyfphndpqntpraswrshgnllftnwlnyyvyqihhhh
hh

    Sequence, based on observed residues (ATOM records): (download) 
    >6mtgB (B:)
pirvpdelpavnflreenvfvmttsraeirplkvlilnlmpkkietenqflrllsnsplq
vdiqllridsresrntpaehlnnfycnfediqdqnfdglivtgaplglvefndvaywpqi
kqvlewskdhvtstlfvcwavqaalnilygipkqtrteklsgvyehhilhphalltrgfd
dsflaphsryadfpaalirdytdleilaeteegdaylfaskdkriafvtghpeydaqtla
qeffrdveagldidvpynyfphndpqntpraswrshgnllftnwlnyyvyqi