PDB entry 6msm

View 6msm on RCSB PDB site
Description: phosphorylated, atp-bound human cystic fibrosis transmembrane conductance regulator (cftr)
Deposited on 2018-10-16, released 2018-11-21
The last revision was dated 2018-12-26, with a file datestamp of 2018-12-21.
Experiment type: EM
Resolution: 3.2 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cystic fibrosis transmembrane conductance regulator
    Species: Homo sapiens [TaxId:9606]
    Gene: CFTR, ABCC7
    Database cross-references and differences (RAF-indexed):
    • Uniprot P13569 (0-End)
      • engineered mutation (1370)
  • Chain 'B':
    Compound: Piece of Molecule-1
    Species: Homo sapiens [TaxId:9606]
    Gene: CFTR, ABCC7
    Database cross-references and differences (RAF-indexed):
    • PDB 6MSM (0-16)
  • Heterogens: MG, ATP, POV, CLR

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6msmA (A:)
mqrsplekasvvsklffswtrpilrkgyrqrlelsdiyqipsvdsadnlseklerewdre
laskknpklinalrrcffwrfmfygiflylgevtkavqplllgriiasydpdnkeersia
iylgiglcllfivrtlllhpaifglhhigmqmriamfsliykktlklssrvldkisigql
vsllsnnlnkfdeglalahfvwiaplqvallmgliwellqasafcglgflivlalfqagl
grmmmkyrdqragkiserlvitsemieniqsvkaycweeamekmienlrqtelkltrkaa
yvryfnssafffsgffvvflsvlpyalikgiilrkifttisfcivlrmavtrqfpwavqt
wydslgainkiqdflqkqeyktleynltttevvmenvtafweegfgelfekakqnnnnrk
tsngddslffsnfsllgtpvlkdinfkiergqllavagstgagktsllmvimgelepseg
kikhsgrisfcsqfswimpgtikeniifgvsydeyryrsvikacqleediskfaekdniv
lgeggitlsggqrarislaravykdadlylldspfgyldvltekeifescvcklmanktr
ilvtskmehlkkadkililhegssyfygtfselqnlqpdfssklmgcdsfdqfsaerrns
iltetlhrfslegdapvswtetkkqsfkqtgefgekrknsilnpinsirkfsivqktplq
mngieedsdeplerrlslvpdseqgeailprisvistgptlqarrrqsvlnlmthsvnqg
qnihrkttastrkvslapqanlteldiysrrlsqetgleiseeineedlkecffddmesi
pavttwntylryitvhkslifvliwclviflaevaaslvvlwllgntplqdkgnsthsrn
nsyaviitstssyyvfyiyvgvadtllamgffrglplvhtlitvskilhhkmlhsvlqap
mstlntlkaggilnrfskdiailddllpltifdfiqlllivigaiavvavlqpyifvatv
pvivafimlrayflqtsqqlkqlesegrspifthlvtslkglwtlrafgrqpyfetlfhk
alnlhtanwflylstlrwfqmriemifviffiavtfisilttgegegrvgiiltlamnim
stlqwavnssidvdslmrsvsrvfkfidmptegkptkstkpykngqlskvmiienshvkk
ddiwpsggqmtvkdltakyteggnailenisfsispgqrvgllgrtgsgkstllsaflrl
lntegeiqidgvswdsitlqqwrkafgvipqkvfifsgtfrknldpyeqwsdqeiwkvad
evglrsvieqfpgkldfvlvdggcvlshghkqlmclarsvlskakillldqpsahldpvt
yqiirrtlkqafadctvilcehrieamlecqqflvieenkvrqydsiqkllnerslfrqa
ispsdrvklfphrnsskckskpqiaalkeeteeevqdtrlsnslevlfq

    Sequence, based on observed residues (ATOM records):
    >6msmA (A:)
mqrsplekasvvsklffswtrpilrkgyrqrlelsdiyqipsvdsadnlseklerewdre
laskknpklinalrrcffwrfmfygiflylgevtkavqplllgriiasydpdnkeersia
iylgiglcllfivrtlllhpaifglhhigmqmriamfsliykktlklssrvldkisigql
vsllsnnlnkfdeglalahfvwiaplqvallmgliwellqasafcglgflivlalfqagl
grmmmkyrdqragkiserlvitsemieniqsvkaycweeamekmienlrqtelkltrkaa
yvryfnssafffsgffvvflsvlpyalikgiilrkifttisfcivlrmavtrqfpwavqt
wydslgainkiqdflqkqeyktleynltttevvmenvtafweegfgelfllgtpvlkdin
fkiergqllavagstgagktsllmvimgelepsegkikhsgrisfcsqfswimpgtiken
iifgvsydeyryrsvikacqleediskfaekdnivlgeggitlsggqrarislaravykd
adlylldspfgyldvltekeifescvcklmanktrilvtskmehlkkadkililhegssy
fygtfselqnlqtwntylryitvhkslifvliwclviflaevaaslvvlwllgntplnns
yaviitstssyyvfyiyvgvadtllamgffrglplvhtlitvskilhhkmlhsvlqapms
tlntlkaggilnrfskdiailddllpltifdfiqlllivigaiavvavlqpyifvatvpv
ivafimlrayflqtsqqlkqlesegrspifthlvtslkglwtlrafgrqpyfetlfhkal
nlhtanwflylstlrwfqmriemifviffiavtfisilttgegegrvgiiltlamnimst
lqwavnssidvdslmrsvsrvfkfidmptegdiwpsggqmtvkdltakyteggnaileni
sfsispgqrvgllgrtgsgkstllsaflrllntegeiqidgvswdsitlqqwrkafgvip
qkvfifsgtfrknldpyeqwsdqeiwkvadevglrsvieqfpgkldfvlvdggcvlshgh
kqlmclarsvlskakillldqpsahldpvtyqiirrtlkqafadctvilcehrieamlec
qqflvieenkvrqydsiqkllnerslfrqaispsdrvklfp

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6msmB (B:)
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