PDB entry 6mqg

View 6mqg on RCSB PDB site
Description: Crystal structure of KRAS V14I-GDP demonstrating open switch 1 conformation - Form 1
Class: hydrolase
Keywords: gtpase kras hydrolysis, hydrolase
Deposited on 2018-10-09, released 2019-07-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-02, with a file datestamp of 2019-09-27.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: GTPase KRas
  Species: Homo sapiens [TaxId:9606]
  Gene: KRAS, KRAS2, RASK2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P01116 (0-166)
    • engineered mutation (11)
  Domains in SCOPe 2.08: d6mqga_
• Heterogens: GDP, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mqgA (A:)
  eyklvvvgaggigksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtagqe
  eysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlps
  rtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhkek