PDB entry 6mpb

View 6mpb on RCSB PDB site
Description: cryo-em structure of the human neutral amino acid transporter asct2
Deposited on 2018-10-05, released 2019-11-06
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: EM
Resolution: 3.84 Å
R-factor: N/A
AEROSPACI score: 0.13 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Neutral amino acid transporter B(0)
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC1A5, ASCT2, M7V1, RDR, RDRC
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Neutral amino acid transporter B(0)
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC1A5, ASCT2, M7V1, RDR, RDRC
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Neutral amino acid transporter B(0)
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC1A5, ASCT2, M7V1, RDR, RDRC
    Database cross-references and differences (RAF-indexed):
  • Heterogens: GLN, NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6mpbA (A:)
mvadpprdskglaaaeptangglalasiedqgaaaggycgsrdqvrrclranllvlltvv
avvagvalglgvsgaggalalgperlsafvfpgelllrllrmiilplvvcsliggaasld
pgalgrlgawallfflvttllasalgvglalalqpgaasaainasvgaagsaenapskev
ldsfldlarnifpsnlvsaafrsysttyeernitgtrvkvpvgqevegmnilglvvfaiv
fgvalrklgpegellirffnsfneatmvlvswimwyapvgimflvagkivemedvgllfa
rlgkyilccllghaihgllvlpliyflftrknpyrflwgivtplatafgtssssatlplm
mkcveenngvakhisrfilpigatvnmdgaalfqcvaavfiaqlsqqsldfvkiitilvt
atassvgaagipaggvltlaiileavnlpvdhislilavdwlvdrsctvlnvegdalgag
llqnyvdrtesrstepeliqvkselpldplpvpteegnpllkhyrgpagdatvasekesv
m

    Sequence, based on observed residues (ATOM records):
    >6mpbA (A:)
dqvrrclranllvlltvvavvagvalglgvsgaggalalgperlsafvfpgelllrllrm
iilplvvcsliggaasldpgalgrlgawallfflvttllasalgvglalalqpgaasaai
nasvgaagsaenapskevldsfldlarnifpsnlvsaafrsysttyeernitgtrvkvpv
gqevegmnilglvvfaivfgvalrklgpegellirffnsfneatmvlvswimwyapvgim
flvagkivemedvgllfarlgkyilccllghaihgllvlpliyflftrknpyrflwgivt
platafgtssssatlplmmkcveenngvakhisrfilpigatvnmdgaalfqcvaavfia
qlsqqsldfvkiitilvtatassvgaagipaggvltlaiileavnlpvdhislilavdwl
vdrsctvlnvegdalgagllqnyvdr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mpbB (B:)
mvadpprdskglaaaeptangglalasiedqgaaaggycgsrdqvrrclranllvlltvv
avvagvalglgvsgaggalalgperlsafvfpgelllrllrmiilplvvcsliggaasld
pgalgrlgawallfflvttllasalgvglalalqpgaasaainasvgaagsaenapskev
ldsfldlarnifpsnlvsaafrsysttyeernitgtrvkvpvgqevegmnilglvvfaiv
fgvalrklgpegellirffnsfneatmvlvswimwyapvgimflvagkivemedvgllfa
rlgkyilccllghaihgllvlpliyflftrknpyrflwgivtplatafgtssssatlplm
mkcveenngvakhisrfilpigatvnmdgaalfqcvaavfiaqlsqqsldfvkiitilvt
atassvgaagipaggvltlaiileavnlpvdhislilavdwlvdrsctvlnvegdalgag
llqnyvdrtesrstepeliqvkselpldplpvpteegnpllkhyrgpagdatvasekesv
m

    Sequence, based on observed residues (ATOM records):
    >6mpbB (B:)
dqvrrclranllvlltvvavvagvalglgvsgaggalalgperlsafvfpgelllrllrm
iilplvvcsliggaasldpgalgrlgawallfflvttllasalgvglalalqpgaasaai
nasvgaagsaenapskevldsfldlarnifpsnlvsaafrsysttyeernitgtrvkvpv
gqevegmnilglvvfaivfgvalrklgpegellirffnsfneatmvlvswimwyapvgim
flvagkivemedvgllfarlgkyilccllghaihgllvlpliyflftrknpyrflwgivt
platafgtssssatlplmmkcveenngvakhisrfilpigatvnmdgaalfqcvaavfia
qlsqqsldfvkiitilvtatassvgaagipaggvltlaiileavnlpvdhislilavdwl
vdrsctvlnvegdalgagllqnyvdr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6mpbC (C:)
mvadpprdskglaaaeptangglalasiedqgaaaggycgsrdqvrrclranllvlltvv
avvagvalglgvsgaggalalgperlsafvfpgelllrllrmiilplvvcsliggaasld
pgalgrlgawallfflvttllasalgvglalalqpgaasaainasvgaagsaenapskev
ldsfldlarnifpsnlvsaafrsysttyeernitgtrvkvpvgqevegmnilglvvfaiv
fgvalrklgpegellirffnsfneatmvlvswimwyapvgimflvagkivemedvgllfa
rlgkyilccllghaihgllvlpliyflftrknpyrflwgivtplatafgtssssatlplm
mkcveenngvakhisrfilpigatvnmdgaalfqcvaavfiaqlsqqsldfvkiitilvt
atassvgaagipaggvltlaiileavnlpvdhislilavdwlvdrsctvlnvegdalgag
llqnyvdrtesrstepeliqvkselpldplpvpteegnpllkhyrgpagdatvasekesv
m

    Sequence, based on observed residues (ATOM records):
    >6mpbC (C:)
dqvrrclranllvlltvvavvagvalglgvsgaggalalgperlsafvfpgelllrllrm
iilplvvcsliggaasldpgalgrlgawallfflvttllasalgvglalalqpgaasaai
nasvgaagsaenapskevldsfldlarnifpsnlvsaafrsysttyeernitgtrvkvpv
gqevegmnilglvvfaivfgvalrklgpegellirffnsfneatmvlvswimwyapvgim
flvagkivemedvgllfarlgkyilccllghaihgllvlpliyflftrknpyrflwgivt
platafgtssssatlplmmkcveenngvakhisrfilpigatvnmdgaalfqcvaavfia
qlsqqsldfvkiitilvtatassvgaagipaggvltlaiileavnlpvdhislilavdwl
vdrsctvlnvegdalgagllqnyvdr