PDB entry 6moe

View 6moe on RCSB PDB site
Description: monomeric darpin e2 complex with epor
Deposited on 2018-10-04, released 2019-06-05
The last revision was dated 2019-06-12, with a file datestamp of 2019-06-07.
Experiment type: XRAY
Resolution: 2.09 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E2 DARPin
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MOE
  • Chain 'B':
    Compound: E2 DARPin
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MOE
  • Chain 'C':
    Compound: erythropoietin receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19235 (5-End)
      • expression tag (4)
      • conflict (49)
      • conflict (161)
  • Chain 'D':
    Compound: erythropoietin receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: EPOR
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19235 (5-End)
      • conflict (49)
      • conflict (161)
  • Heterogens: PO4, EDO, EPE, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6moeA (A:)
mgsdlgkkllkaaragqddevrilmangadvnatdiwdatplhlaalighleivevllkn
gadvnasditgttplhlaatmghleivevllkygadvnaydlngatplhlaarmghveiv
evllkygadvnaqdkfgktafdisidngnedlaeilqaaalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6moeA (A:)
gsdlgkkllkaaragqddevrilmangadvnatdiwdatplhlaalighleivevllkng
advnasditgttplhlaatmghleivevllkygadvnaydlngatplhlaarmghveive
vllkygadvnaqdkfgktafdisidngnedlaeilqaaale

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6moeB (B:)
mgsdlgkkllkaaragqddevrilmangadvnatdiwdatplhlaalighleivevllkn
gadvnasditgttplhlaatmghleivevllkygadvnaydlngatplhlaarmghveiv
evllkygadvnaqdkfgktafdisidngnedlaeilqaaalehhhhhh

    Sequence, based on observed residues (ATOM records):
    >6moeB (B:)
gsdlgkkllkaaragqddevrilmangadvnatdiwdatplhlaalighleivevllkng
advnasditgttplhlaatmghleivevllkygadvnaydlngatplhlaarmghveive
vllkygadvnaqdkfgktafdisidngnedlaeilqaaale

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6moeC (C:)
fagsadpkfeskaallaargpeellcfterledlvcfweeaasagvgpgqysfsyqlede
pwklcrlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvlld
apvglvarladesghvvlrwlpppetpmtshiryevdvsagqgagsvqrveilegrtecv
lsnlrgrtrytfavrarmaepsfggfwsawsepvslltpsdldkekaaa

    Sequence, based on observed residues (ATOM records):
    >6moeC (C:)
adpkfeskaallaargpeellcfterledlvcfweeaasagvgpgqysfsyqledepwkl
crlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvlldapvg
lvarladesghvvlrwlpppetpmtshiryevdvsagqgagsvqrveilegrtecvlsnl
rgrtrytfavrarmaepsfggfwsawsepvslltpsd

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6moeD (D:)
fagsadpkfeskaallaargpeellcfterledlvcfweeaasagvgpgqysfsyqlede
pwklcrlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvlld
apvglvarladesghvvlrwlpppetpmtshiryevdvsagqgagsvqrveilegrtecv
lsnlrgrtrytfavrarmaepsfggfwsawsepvslltpsdldkekaaa

    Sequence, based on observed residues (ATOM records):
    >6moeD (D:)
dpkfeskaallaargpeellcfterledlvcfweeaasagvgpgqysfsyqledepwklc
rlhqaptargavrfwcslptadtssfvplelrvtaasgapryhrvihinevvlldapvgl
varladesghvvlrwlpppetpmtshiryevdvsagqgagsvqrveilegrtecvlsnlr
grtrytfavrarmaepsfggfwsawsepvslltpsd