PDB entry 6mo1

View 6mo1 on RCSB PDB site
Description: structure of dengue virus protease with an allosteric inhibitor that blocks replication
Deposited on 2018-10-03, released 2019-05-15
The last revision was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 3 Å
R-factor: N/A
AEROSPACI score: 0.12 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: FLAVIVIRUS_NS2B/Peptidase S7
    Species: DENGUE VIRUS 2 [TaxId:11060]
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3RFT3 (6-End)
      • expression tag (5)
    • Uniprot Q91H74
      • conflict (228)
  • Chain 'B':
    Compound: FLAVIVIRUS_NS2B/Peptidase S7
    Species: DENGUE VIRUS 2 [TaxId:11060]
    Database cross-references and differences (RAF-indexed):
    • Uniprot B3RFT3 (6-End)
      • expression tag (5)
    • Uniprot Q91H74
      • conflict (228)
  • Heterogens: I16

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6mo1A (A:)
gshmlmadleleraadvrweeqaeisgsspilsitisedgsmsikneeeeqtlggggsgg
ggagvlwdvpspppvgkaeledgayrikqkgilgysqigagvykegtfhtmwhvtrgavl
mhkgkriepswadvkkdlisygggwklegewkegeevqvlalepgknpravqtkpglfkt
ntgtigavsldfspgtsgspivdkkgkvvglygngvvtrsgayvsaianteksiednpei
eddifrk

    Sequence, based on observed residues (ATOM records):
    >6mo1A (A:)
madleleraadvrweeqaeisgssledgayrikqkgilgysqigagvykegtfhtmwhvt
rgavlmhkgkriepswadvkkdlisygggwklegewkegeevqvlalepgknpravqtkp
glfktntgtigavsldfspgtsgspivdkkgkvvglygiantek

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mo1B (B:)
gshmlmadleleraadvrweeqaeisgsspilsitisedgsmsikneeeeqtlggggsgg
ggagvlwdvpspppvgkaeledgayrikqkgilgysqigagvykegtfhtmwhvtrgavl
mhkgkriepswadvkkdlisygggwklegewkegeevqvlalepgknpravqtkpglfkt
ntgtigavsldfspgtsgspivdkkgkvvglygngvvtrsgayvsaianteksiednpei
eddifrk

    Sequence, based on observed residues (ATOM records):
    >6mo1B (B:)
madleleraadvrweeqaeisgssledgayrikqkgilgysqigagvykegtfhtmwhvt
rgavlmhkgkriepswadvkkdlisygggwklegewkegeevqvlalepgknpravqtkp
glfktntgtigavsldfspgtsgspivdkkgkvvglygiantek