PDB entry 6mml

View 6mml on RCSB PDB site
Description: diheteromeric nmda receptor glun1/glun2a in the '2-knuckle-asymmetric' conformation, in complex with glycine and glutamate, in the presence of 1 micromolar zinc chloride, and at ph 7.4
Deposited on 2018-09-30, released 2018-11-28
The last revision was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: EM
Resolution: 7.14 Å
R-factor: N/A
AEROSPACI score: 0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor ionotropic, NMDA 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin1, Nmdar1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Glutamate receptor ionotropic, NMDA 2A
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin2a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00959 (Start-836)
      • conflict (757)
  • Chain 'C':
    Compound: Glutamate receptor ionotropic, NMDA 1
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin1, Nmdar1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Glutamate receptor ionotropic, NMDA 2A
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Grin2a
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00959 (Start-836)
      • conflict (757)
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6mmlA (A:)
mstmhlltfallfscsfaraacdpkivnigavlstrkheqmfreavnqankrhgswkiql
natsvthkpnaiqmalsvcedlissqvyailvshpptpndhftptpvsytagfyripvlg
lttrmsiysdksihlsflrtvppyshqssvwfemmrvynwnhiillvsddhegraaqkrl
etlleereskaekvlqfdpgtknvtallmearelearviilsaseddaatvyraaamlnm
tgsgyvwlvgereisgnalryapdgiiglqlingknesahisdavgvvaqavhelleken
itdpprgcvgntniwktgplfkrvlmsskyadgvtgrvefnedgdrkfanysimnlqnrk
lvqvgiyngthvipndrkiiwpggetekprgyqmstrlkivtihqepfvyvkptmsdgtc
keeftvngdpvkkvictgpndtspgsprhtvpqccygfcidlliklartmnftyevhlva
dgkfgtqervnnsnkkewngmmgellsgqadmivapltinneraqyiefskpfkyqglti
lvkkeiprstldsfmqpfqstlwllvglsvhvvavmlylldrfspfgrfkvnseeeeeda
ltlssamwfswgvllnsgigegaprsfsarilgmvwagfamiivasytanlaaflvldrp
eeritgindprlrnpsdkfiyatvkqssvdiyfrrqvelstmyrhmekhnyesaaeaiqa
vrdnklhafiwdsavlefeasqkcdlvttgelffrsgfgigmrkdspwkqnvslsilksh
engfmedldktwvryqecdsrsnapatltfenmagvfmlvaggivagiflifieiayk

    Sequence, based on observed residues (ATOM records):
    >6mmlA (A:)
kivnigavlstrkheqmfreavnqankrhgswkiqlnatsvthkpnaiqmalsvcedlis
sqvyailvshpptpndhftptpvsytagfyripvlglttrmsiysdksihlsflrtvppy
shqssvwfemmrvynwnhiillvsddhegraaqkrletlleereskaekvlqfdpgtknv
tallmearelearviilsaseddaatvyraaamlnmtgsgyvwlvgereisgnalryapd
giiglqlingknesahisdavgvvaqavhellekenitdpprgcvgntniwktgplfkrv
lmsskyadgvtgrvefnedgdrkfanysimnlqnrklvqvgiyngthvipndrkiiwpgg
etekprgyqmstrlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtsp
gsprhtvpqccygfcidlliklartmnftyevhlvadgkfgtqervnnsnkkewngmmge
llsgqadmivapltinneraqyiefskpfkyqgltilvkkstlwllvglsvhvvavmlyl
ldrfspltlssamwfswgvllnfsarilgmvwagfamiivasytanlaaflvldrpeeri
tgindprlrnpsdkfiyatvkqssvdiyfrrqvelstmyrhmekhnyesaaeaiqavrdn
klhafiwdsavlefeasqkcdlvttgelffrsgfgigmrkdspwkqnvslsilkshengf
medldktwvryqetltfenmagvfmlvaggivagiflifieiayk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mmlB (B:)
mgrlgywtllvlpallvwrdpaqnaaaekgppalniavllghshdvterelrnlwgpeqa
tglpldvnvvallmnrtdpkslithvcdlmsgarihglvfgddtdqeavaqmldfissqt
fipilgihggasmimadkdptstffqfgasiqqqatvmlkimqdydwhvfslvttifpgy
rdfisfikttvdnsfvgwdmqnvitldtsfedaktqvqlkkihssvillycskdeavlil
searslgltgydffwivpslvsgntelipkefpsglisvsyddwdyslearvrdglgilt
taassmlekfsyipeakascygqaekpetplhtlhqfmvnvtwdgkdlsfteegyqvhpr
lvvivlnkdrewekvgkwenqtlslrhavwpryksfsdcepddnhlsivtleeapfvive
didpltetcvrntvpcrkfvkinnstnegmnvkkcckgfcidilkklsrtvkftydlylv
tngkhgkkvnnvwngmigevvyqravmavgsltineersevvdfsvpfvetgisvmvsrs
ngtvspsaflepfsasvwvmmfvmllivsaiavfvfeyfspvgynrnlakgkaphgpsft
igkaiwllwglvfnnsvpvqnpkgttskimvsvwaffaviflasytanlaafmiqeefvd
qvtglsdkkfqrphdysppfrfgtvpngsternirnnypymhqymtrfnqrgvedalvsl
ktgkldafiydaavlnykagrdegcklvtigsgyifattgygialqkgspwkrqidlall
qfvgdgemeeletlwltgichneknevmssqldidnmagvfymlaaamalslitfiw

    Sequence, based on observed residues (ATOM records):
    >6mmlB (B:)
lniavllghshdvterelrnlwgpeqatglpldvnvvallmnrtdpkslithvcdlmsga
rihglvfgddtdqeavaqmldfissqtfipilgihggasmimadkdptstffqfgasiqq
qatvmlkimqdydwhvfslvttifpgyrdfisfikttvdnsfvgwdmqnvitldtsfeda
ktqvqlkkihssvillycskdeavlilsearslgltgydffwivpslvsgntelipkefp
sglisvsyddwdyslearvrdglgilttaassmlekfsyipeakascygqplhtlhqfmv
nvtwdgkdlsfteegyqvhprlvvivlnkdrewekvgkwenqtlslrhavwpryksfsdc
epddnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckgf
cidilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineers
evvdfsvpfvetgisvmvsasvwvmmfvmllivsaiavfvfeyfsftigkaiwllwglvf
nnsvpvqnpkgttskimvsvwaffaviflasytanlaafmiqeefvdqvtglsdkkfqrp
hdysppfrfgtvpngsternirnnypymhqymtrfnqrgvedalvslktgkldafiydaa
vlnykagrdegcklvtigsgyifattgygialqkgspwkrqidlallqfvgdgemeelet
lwltgicssqldidnmagvfymlaaamalslitfiw

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6mmlC (C:)
mstmhlltfallfscsfaraacdpkivnigavlstrkheqmfreavnqankrhgswkiql
natsvthkpnaiqmalsvcedlissqvyailvshpptpndhftptpvsytagfyripvlg
lttrmsiysdksihlsflrtvppyshqssvwfemmrvynwnhiillvsddhegraaqkrl
etlleereskaekvlqfdpgtknvtallmearelearviilsaseddaatvyraaamlnm
tgsgyvwlvgereisgnalryapdgiiglqlingknesahisdavgvvaqavhelleken
itdpprgcvgntniwktgplfkrvlmsskyadgvtgrvefnedgdrkfanysimnlqnrk
lvqvgiyngthvipndrkiiwpggetekprgyqmstrlkivtihqepfvyvkptmsdgtc
keeftvngdpvkkvictgpndtspgsprhtvpqccygfcidlliklartmnftyevhlva
dgkfgtqervnnsnkkewngmmgellsgqadmivapltinneraqyiefskpfkyqglti
lvkkeiprstldsfmqpfqstlwllvglsvhvvavmlylldrfspfgrfkvnseeeeeda
ltlssamwfswgvllnsgigegaprsfsarilgmvwagfamiivasytanlaaflvldrp
eeritgindprlrnpsdkfiyatvkqssvdiyfrrqvelstmyrhmekhnyesaaeaiqa
vrdnklhafiwdsavlefeasqkcdlvttgelffrsgfgigmrkdspwkqnvslsilksh
engfmedldktwvryqecdsrsnapatltfenmagvfmlvaggivagiflifieiayk

    Sequence, based on observed residues (ATOM records):
    >6mmlC (C:)
kivnigavlstrkheqmfreavnqankrhgswkiqlnatsvthkpnaiqmalsvcedlis
sqvyailvshpptpndhftptpvsytagfyripvlglttrmsiysdksihlsflrtvppy
shqssvwfemmrvynwnhiillvsddhegraaqkrletlleereskaekvlqfdpgtknv
tallmearelearviilsaseddaatvyraaamlnmtgsgyvwlvgereisgnalryapd
giiglqlingknesahisdavgvvaqavhellekenitdpprgcvgntniwktgplfkrv
lmsskyadgvtgrvefnedgdrkfanysimnlqnrklvqvgiyngthvipndrkiiwpgg
etekprgyqmstrlkivtihqepfvyvkptmsdgtckeeftvngdpvkkvictgpndtsp
gsprhtvpqccygfcidlliklartmnftyevhlvadgkfgtqervnnsnkkewngmmge
llsgqadmivapltinneraqyiefskpfkyqgltilvkkstlwllvglsvhvvavmlyl
ldrfspltlssamwfswgvllnsfsarilgmvwagfamiivasytanlaaflvldrpeer
itgindprlrnpsdkfiyatvkqssvdiyfrrqvelstmyrhmekhnyesaaeaiqavrd
nklhafiwdsavlefeasqkcdlvttgelffrsgfgigmrkdspwkqnvslsilksheng
fmedldktwvryqeltfenmagvfmlvaggivagiflifieiayk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6mmlD (D:)
mgrlgywtllvlpallvwrdpaqnaaaekgppalniavllghshdvterelrnlwgpeqa
tglpldvnvvallmnrtdpkslithvcdlmsgarihglvfgddtdqeavaqmldfissqt
fipilgihggasmimadkdptstffqfgasiqqqatvmlkimqdydwhvfslvttifpgy
rdfisfikttvdnsfvgwdmqnvitldtsfedaktqvqlkkihssvillycskdeavlil
searslgltgydffwivpslvsgntelipkefpsglisvsyddwdyslearvrdglgilt
taassmlekfsyipeakascygqaekpetplhtlhqfmvnvtwdgkdlsfteegyqvhpr
lvvivlnkdrewekvgkwenqtlslrhavwpryksfsdcepddnhlsivtleeapfvive
didpltetcvrntvpcrkfvkinnstnegmnvkkcckgfcidilkklsrtvkftydlylv
tngkhgkkvnnvwngmigevvyqravmavgsltineersevvdfsvpfvetgisvmvsrs
ngtvspsaflepfsasvwvmmfvmllivsaiavfvfeyfspvgynrnlakgkaphgpsft
igkaiwllwglvfnnsvpvqnpkgttskimvsvwaffaviflasytanlaafmiqeefvd
qvtglsdkkfqrphdysppfrfgtvpngsternirnnypymhqymtrfnqrgvedalvsl
ktgkldafiydaavlnykagrdegcklvtigsgyifattgygialqkgspwkrqidlall
qfvgdgemeeletlwltgichneknevmssqldidnmagvfymlaaamalslitfiw

    Sequence, based on observed residues (ATOM records):
    >6mmlD (D:)
lniavllghshdvterelrnlwgpeqatglpldvnvvallmnrtdpkslithvcdlmsga
rihglvfgddtdqeavaqmldfissqtfipilgihggasmimadkdptstffqfgasiqq
qatvmlkimqdydwhvfslvttifpgyrdfisfikttvdnsfvgwdmqnvitldtsfeda
ktqvqlkkihssvillycskdeavlilsearslgltgydffwivpslvsgntelipkefp
sglisvsyddwdyslearvrdglgilttaassmlekfsyipeakascygqplhtlhqfmv
nvtwdgkdlsfteegyqvhprlvvivlnkdrewekvgkwenqtlslrhavwpryksfsdc
epddnhlsivtleeapfvivedidpltetcvrntvpcrkfvkinnstnegmnvkkcckgf
cidilkklsrtvkftydlylvtngkhgkkvnnvwngmigevvyqravmavgsltineers
evvdfsvpfvetgisvmvsasvwvmmfvmllivsaiavfvfeyfsftigkaiwllwglvf
nnsvpvqnpkgttskimvsvwaffaviflasytanlaafmiqeefvdqvtglsdkkfqrp
hdysppfrfgtvpngsternirnnypymhqymtrfnqrgvedalvslktgkldafiydaa
vlnykagrdegcklvtigsgyifattgygialqkgspwkrqidlallqfvgdgemeelet
lwltgicqldidnmagvfymlaaamalslitfiw