PDB entry 6mm8

View 6mm8 on RCSB PDB site
Description: Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 K2879A, S2813D phosphomimetic (2699-2904) crystal form 2
Class: protein binding
Keywords: Kinase, complex, ion channel, enzyme, PROTEIN BINDING
Deposited on 2018-09-29, released 2019-05-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-08, with a file datestamp of 2020-01-03.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'C':
    Compound: cAMP-dependent protein kinase catalytic subunit alpha
    Species: Mus musculus [TaxId:10090]
    Gene: Prkaca, Pkaca
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05132 (3-338)
      • expression tag (2)
    Domains in SCOPe 2.08: d6mm8c1, d6mm8c2
  • Chain 'D':
    Compound: Ryanodine receptor 2
    Species: Mus musculus [TaxId:10090]
    Gene: Ryr2
    Database cross-references and differences (RAF-indexed):
    • Uniprot E9Q401 (3-208)
      • engineered mutation (117)
      • engineered mutation (183)
  • Heterogens: ANP, PEG, ACY, EDO, CL, HOH

PDB Chain Sequences:

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6mm8C (C:)
snavkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyam
kildkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfsh
lrrigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrv
kgrtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekiv
sgkvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkve
apfipkfkgpgdtsnfddyeeeeirvsinekcgkeftef

    Sequence, based on observed residues (ATOM records): (download) 
    >6mm8C (C:)
avkeflakakedflkkwetpsqntaqldqfdriktlgtgsfgrvmlvkhkesgnhyamki
ldkqkvvklkqiehtlnekrilqavnfpflvklefsfkdnsnlymvmeyvaggemfshlr
rigrfsepharfyaaqivltfeylhsldliyrdlkpenllidqqgyiqvtdfgfakrvkg
rtwtlcgtpeylapeiilskgynkavdwwalgvliyemaagyppffadqpiqiyekivsg
kvrfpshfssdlkdllrnllqvdltkrfgnlkngvndiknhkwfattdwiaiyqrkveap
fipkfyeeeeirvsinekcgkeftef

  • Chain 'D':
    No sequence available.