PDB entry 6mlb

View 6mlb on RCSB PDB site
Description: Crystal structure of the holo retinal-bound domain-swapped dimer Q108K:K40L:T51F mutant of human cellular retinol binding protein II
Class: lipid binding protein
Keywords: iLBP, Protein Switch, LIPID BINDING PROTEIN
Deposited on 2018-09-27, released 2019-10-16
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-10-16, with a file datestamp of 2019-10-11.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.07: d6mlba_
• Chain 'B':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.07: d6mlbb_
• Chain 'C':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.07: d6mlbc_
• Chain 'D':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.07: d6mlbd_
• Heterogens: GOL, ACT, RET, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mlbA (A:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkfkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mlbB (B:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkfkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mlbC (C:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkfkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mlbD (D:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkfkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk