PDB entry 6mkv

View 6mkv on RCSB PDB site
Description: Crystal structure of Retinal-bound holo Q108K:K40L:T51W domain-swapped dimer of human cellular retinol binding protein 2
Class: lipid binding protein
Keywords: iLBP, Protein Switch, CYTOSOLIC PROTEIN, LIPID BINDING PROTEIN
Deposited on 2018-09-26, released 2019-10-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.08: d6mkva_
• Chain 'B':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.08: d6mkvb_
• Chain 'C':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.08: d6mkvc_
• Chain 'D':
  Compound: Retinol-binding protein 2
  Species: Homo sapiens [TaxId:9606]
  Gene: RBP2, CRBP2
  Database cross-references and differences (RAF-indexed):
  • Uniprot P50120 (0-132)
    • engineered mutation (39)
    • engineered mutation (50)
    • engineered mutation (107)
  Domains in SCOPe 2.08: d6mkvd_
• Heterogens: RET, ACT, GOL, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mkvA (A:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkwkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mkvB (B:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkwkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk
  

  
  
• Chain 'C':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mkvC (C:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkwkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk
  

  
  
• Chain 'D':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >6mkvD (D:)
  trdqngtwemesnenfegymkaldidfatrkiavrltqtlvidqdgdnfkwkttstfrny
  dvdftvgvefdeytksldnrhvkalvtwegdvlvcvqkgekenrgwkkwiegdklylelt
  cgdqvcrqvfkkk