PDB entry 6mkn

View 6mkn on RCSB PDB site
Description: structure of the thermus thermophilus 30s ribosomal subunit complexed with an inosine (i34) modified anticodon stem loop (asl) of escherichia coli transfer rna arginine 2 (trnaarg2) bound to an mrna with an cgu-codon in the a-site and paromomycin
Deposited on 2018-09-25, released 2019-04-24
The last revision was dated 2020-03-11, with a file datestamp of 2020-03-06.
Experiment type: XRAY
Resolution: 3.46 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 16s rRNA
    Species: Thermus thermophilus HB8 [TaxId:300852]
  • Chain 'B':
    Compound: 30S ribosomal protein S2
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: 30S ribosomal protein S3
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: 30S ribosomal protein S4
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: 30S ribosomal protein S5
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: 30S ribosomal protein S6
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: 30S ribosomal protein S7
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: 30S ribosomal protein S8
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: 30S ribosomal protein S9
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P80374 (Start-127)
      • conflict (57)
  • Chain 'J':
    Compound: 30S ribosomal protein S10
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: 30S ribosomal protein S11
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: 30S ribosomal protein S12
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: 30S ribosomal protein S13
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: 30s ribosomal protein s14 type z
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: 30S ribosomal protein S15
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: 30S ribosomal protein S16
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: 30S ribosomal protein S17
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0DOY7 (Start-104)
      • conflict (95)
  • Chain 'R':
    Compound: 30S ribosomal protein S18
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q5SLQ0 (Start-87)
      • conflict (59)
  • Chain 'S':
    Compound: 30S ribosomal protein S19
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'T':
    Compound: 30S ribosomal protein S20
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'V':
    Compound: 30S ribosomal protein Thx
    Species: Thermus thermophilus HB8 [TaxId:300852]
    Database cross-references and differences (RAF-indexed):
  • Chain 'W':
    Compound: mRNA A-site fragment
    Species: Escherichia coli, synthetic [TaxId:562]
  • Chain 'X':
    Compound: tRNA ASL Escherichia coli Arg2
    Species: Escherichia coli, synthetic [TaxId:562]
  • Heterogens: PAR, MG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6mknB (B:)
mpveitvkelleagvhfgherkrwnpkfaryiyaerngihiidlqktmeelertfrfied
lamrggtilfvgtkkqaqdivrmeaeragmpyvnqrwlggmltnfktisqrvhrleelea
lfaspeieerpkkeqvrlkhelerlqkylsgfrllkrlpdaifvvdptkeaiavrearkl
fipvialadtdsdpdlvdyiipgnddairsiqlilsravdliiqarggvvepspsyalvq
eaeatetpegesevea

    Sequence, based on observed residues (ATOM records):
    >6mknB (B:)
vkelleagvhfgherkrwnpkfaryiyaerngihiidlqktmeelertfrfiedlamrgg
tilfvgtkkqaqdivrmeaeragmpyvnqrwlggmltnfktisqrvhrleelealfaspe
ieerpkkeqvrlkhelerlqkylsgfrllkrlpdaifvvdptkeaiavrearklfipvia
ladtdsdpdlvdyiipgnddairsiqlilsravdliiqarggvvepspsyalvq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6mknC (C:)
mgnkihpigfrlgitrdwesrwyagkkqyrhllledqrirgllekelysaglarvdiera
adnvavtvhvakpgvvigrggerirvlreelakltgknvalnvqevqnpnlsaplvaqrv
aeqierrfavrraikqavqrvmesgakgakvivsgriggaeqartewaaqgrvplhtlra
nidygfalarttygvlgvkayiflgeviggqkpkarpelpkaeerprrrrpavrvkkee

    Sequence, based on observed residues (ATOM records):
    >6mknC (C:)
gnkihpigfrlgitrdwesrwyagkkqyrhllledqrirgllekelysaglarvdieraa
dnvavtvhvakpgvvigrggerirvlreelakltgknvalnvqevqnpnlsaplvaqrva
eqierrfavrraikqavqrvmesgakgakvivsgriggaeqartewaaqgrvplhtlran
idygfalarttygvlgvkayiflgev

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6mknD (D:)
mgryigpvcrlcrregvklylkgercyspkcamerrpyppgqhgqkrarrpsdyavrlre
kqklrriygiserqfrnlfeeaskkkgvtgsvflgllesrldnvvyrlgfavsrrqarql
vrhghitvngrrvdlpsyrvrpgdeiavaeksrnlelirqnleamkgrkvgpwlsldveg
mkgkflrlpdredlalpvneqlviefysr

    Sequence, based on observed residues (ATOM records):
    >6mknD (D:)
gryigpvcrlcrregvklylkgercyspkcamerrpyppgqhgqkrarrpsdyavrlrek
qklrriygiserqfrnlfeeaskkkgvtgsvflgllesrldnvvyrlgfavsrrqarqlv
rhghitvngrrvdlpsyrvrpgdeiavaeksrnlelirqnleamkgrkvgpwlsldvegm
kgkflrlpdredlalpvneqlviefysr

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6mknE (E:)
mpetdfeekmilirrtarmqaggrrfrfgalvvvgdrqgrvglgfgkapevplavqkagy
yarrnmvevplqngtipheievefgaskivlkpaapgtgviagavprailelagvtdilt
kelgsrnpiniayatmealrqlrtkadverlrkgeahaqaqg

    Sequence, based on observed residues (ATOM records):
    >6mknE (E:)
dfeekmilirrtarmqaggrrfrfgalvvvgdrqgrvglgfgkapevplavqkagyyarr
nmvevplqngtipheievefgaskivlkpaapgtgviagavprailelagvtdiltkelg
srnpiniayatmealrqlrtkadverlrkg

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records:
    >6mknF (F:)
mrryevnivlnpnldqsqlalekeiiqralenygarvekveelglrrlaypiakdpqgyf
lwyqvempedrvndlarelrirdnvrrvmvvksqepflana

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6mknG (G:)
marrrraevrqlqpdlvygdvlvtafinkimrdgkknlaarifydackiiqektgqeplk
vfkqavenvkprmevrsrrvgganyqvpmevsprrqqslalrwlvqaanqrperraavri
ahelmdaaegkggavkkkedvermaeanrayahyrw

    Sequence, based on observed residues (ATOM records):
    >6mknG (G:)
arrrraevrqlqpdlvygdvlvtafinkimrdgkknlaarifydackiiqektgqeplkv
fkqavenvkprmevrsrrvgganyqvpmevsprrqqslalrwlvqaanqrperraavria
helmdaaegkggavkkkedvermaeanrayahyrw

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records:
    >6mknH (H:)
mltdpiadmltrirnatrvykestdvpasrfkeeilrilaregfikgyervdvdgkpylr
vylkygprrqgpdprpeqvihhirriskpgrrvyvgvkeiprvrrglgiailstskgvlt
drearklgvggelicevw

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6mknI (I:)
meqyygtgrrkeavarvflrpgngkvtvngqdfneyfqglvravaaleplravdalgrfd
ayitvrgggksgqidaiklgiaralvqynpdyraklkplgfltrdarvverkkygkhkar
rapqyskr

    Sequence, based on observed residues (ATOM records):
    >6mknI (I:)
eqyygtgrrkeavarvflrpgngkvtvngqdfneyfqglvravaaleplravdalgrfda
yitvrgggksgqidaiklgiaralvqynpdyraklkplgfltrdarvverkkygkhkarr
apqyskr

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6mknJ (J:)
mpkiriklrgfdhktldasaqkiveaarrsgaqvsgpiplptrvrrftvirgpfkhkdsr
ehfelrthnrlvdiinpnrktieqlmtldlptgveieiktvgggr

    Sequence, based on observed residues (ATOM records):
    >6mknJ (J:)
kiriklrgfdhktldasaqkiveaarrsgaqvsgpiplptrvrrftvirgpfkhkdsreh
felrthnrlvdiinpnrktieqlmtldlptgveieikt

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6mknK (K:)
makkpskkkvkrqvasgrayihasynntivtitdpdgnpitwssggvigykgsrkgtpya
aqlaaldaakkamaygmqsvdvivrgtgagreqairalqasglqvksivddtpvphngcr
pkkkfrkas

    Sequence, based on observed residues (ATOM records):
    >6mknK (K:)
krqvasgrayihasynntivtitdpdgnpitwssggvigykgsrkgtpyaaqlaaldaak
kamaygmqsvdvivrgtgagreqairalqasglqvksivddtpvphngcrpkkkfrkas

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6mknL (L:)
mptinqlvrkgrekvrkkskvpalkgapfrrgvctvvrtvtpkkpnsalrkvakvrltsg
yevtayipgeghnlqehsvvlirggrvkdlpgvryhivrgvydaagvkdrkksrskygtk
kpkeaaktaakk

    Sequence, based on observed residues (ATOM records):
    >6mknL (L:)
ptinqlvrkgrekvrkkskvpalkgapfrrgvctvvrtvtpkkpnsalrkvakvrltsgy
evtayipgeghnlqehsvvlirggrvkdlpgvryhivrgvydaagvkdrkksrskygtkk
pkea

  • Chain 'M':
    Sequence, based on SEQRES records:
    >6mknM (M:)
mariagveiprnkrvdvaltyiygigkarakealektginpatrvkdlteaevvrlreyv
entwklegelraevaanikrlmdigcyrglrhrrglpvrgqrtrtnartrkgprktvagk
kkaprk

    Sequence, based on observed residues (ATOM records):
    >6mknM (M:)
ariagveiprnkrvdvaltyiygigkarakealektginpatrvkdlteaevvrlreyve
ntwklegelraevaanikrlmdigcyrglrhrrglpvrgqrtrtnartrkgprktvagkk
kaprk

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6mknN (N:)
markaliekakrtpkfkvraytrcvrcgrarsvyrffglcriclrelahkgqlpgvrkas
w

    Sequence, based on observed residues (ATOM records):
    >6mknN (N:)
arkaliekakrtpkfkvraytrcvrcgrarsvyrffglcriclrelahkgqlpgvrkasw

  • Chain 'O':
    Sequence, based on SEQRES records:
    >6mknO (O:)
mpitkeekqkviqefarfpgdtgstevqvalltlrinrlsehlkvhkkdhhshrgllmmv
gqrrrllrylqredperyralieklgirg

    Sequence, based on observed residues (ATOM records):
    >6mknO (O:)
pitkeekqkviqefarfpgdtgstevqvalltlrinrlsehlkvhkkdhhshrgllmmvg
qrrrllrylqredperyralieklgirg

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6mknP (P:)
mvkirlarfgskhnphyrivvtdarrkrdgkyiekigyydprkttpdwlkvdverarywl
svgaqptdtarrllrqagvfrqearega

    Sequence, based on observed residues (ATOM records):
    >6mknP (P:)
mvkirlarfgskhnphyrivvtdarrkrdgkyiekigyydprkttpdwlkvdverarywl
svgaqptdtarrllrqagvfrqe

  • Chain 'Q':
    Sequence, based on SEQRES records:
    >6mknQ (Q:)
mpkkvltgvvvsdkmqktvtvlverqfphplygkvikrskkylahdpeekyklgdvveii
esrpiskrkrfrvlrlvesgrmdlvekylirrqnyqslskrggka

    Sequence, based on observed residues (ATOM records):
    >6mknQ (Q:)
pkkvltgvvvsdkmqktvtvlverqfphplygkvikrskkylahdpeekyklgdvveiie
srpiskrkrfrvlrlvesgrmdlvekylirrqnyqslskrggka

  • Chain 'R':
    Sequence, based on SEQRES records:
    >6mknR (R:)
mstknakpkkeaqrrpsrkakvkatlgefdlrdyrnvevlkrflsetgkilprrrtglsg
keqrilaktikrarilgllpfteklvrk

    Sequence, based on observed residues (ATOM records):
    >6mknR (R:)
psrkakvkatlgefdlrdyrnvevlkrflsetgkilprrrtglsgkeqrilaktikrari
lgllpfteklvrk

  • Chain 'S':
    Sequence, based on SEQRES records:
    >6mknS (S:)
mprslkkgvfvddhllekvlelnakgekrliktwsrrstivpemvghtiavyngkqhvpv
yitenmvghklgefaptrtyrghgkeakatkkk

    Sequence, based on observed residues (ATOM records):
    >6mknS (S:)
prslkkgvfvddhllekvlelnakgekrliktwsrrstivpemvghtiavyngkqhvpvy
itenmvghklgefaptrtyr

  • Chain 'T':
    Sequence, based on SEQRES records:
    >6mknT (T:)
maqkkpkrnlsalkrhrqslkrrlrnkakksaiktlskkaiqlaqegkaeealkimrkae
slidkaakgstlhknaaarrksrlmrkvrqlleaagapliggglsa

    Sequence, based on observed residues (ATOM records):
    >6mknT (T:)
rnlsalkrhrqslkrrlrnkakksaiktlskkaiqlaqegkaeealkimrkaeslidkaa
kgstlhknaaarrksrlmrkvrqlleaagapliggglsa

  • Chain 'V':
    Sequence, based on SEQRES records:
    >6mknV (V:)
mgkgdrrtrrgkiwrgtygkyrprkkk

    Sequence, based on observed residues (ATOM records):
    >6mknV (V:)
gkgdrrtrrgkiwrgtygkyrprk

  • Chain 'W':
    No sequence available.

  • Chain 'X':
    No sequence available.