PDB entry 6meg

View 6meg on RCSB PDB site
Description: Crystal structure of human monoclonal antibody HEPC46
Class: immune system
Keywords: HCV glycoprotein, broadly neutralizing antibodies, IMMUNE SYSTEM
Deposited on 2018-09-06, released 2018-11-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 1.41 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: antibody HEPC46 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MEG (0-End)
    Domains in SCOPe 2.08: d6megh_
  • Chain 'L':
    Compound: antibody HEPC46 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MEG (0-End)
    Domains in SCOPe 2.08: d6megl1, d6megl2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6megH (H:)
qvqlvqsgaevkkpgasvkvsckasgyiftshgiswvrqapgqglewmgwisvyngytny
aqnlqgrvtmttdtststaymelrslrsddtavyfcarasqirgvdywgqgtlvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6megH (H:)
qvqlvqsgaevkkpgasvkvsckasgyiftshgiswvrqapgqglewmgwisvyngytny
aqnlqgrvtmttdtststaymelrslrsddtavyfcarasqirgvdywgqgtlvtvssas
tkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssgl
yslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6megL (L:)
qsvltqppsasgtpgqrvtiscsgsssnigsnyvywyqqfpgtapklliygnnqrpsgvp
drfsgsksgtsaslaisglrsedeadyycaawddslsgpwvfgggtqvtvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvaptecs

    Sequence, based on observed residues (ATOM records): (download) 
    >6megL (L:)
qsvltqppsasgtpgqrvtiscsgsssnigsnyvywyqqfpgtapklliygnnqrpsgvp
drfsgsksgtsaslaisglrsedeadyycaawddslsgpwvfgggtqvtvlgqpkaapsv
tlfppsseelqankatlvclisdfypgavtvawkadsspvkagvetttpskqsnnkyaas
sylsltpeqwkshrsyscqvthegstvektvap