PDB entry 6med

View 6med on RCSB PDB site
Description: Crystal structure of broadly neutralizing antibody HEPC3
Class: immune system
Keywords: HCV glycoprotein, broadly neutralizing antibodies, IMMUNE SYSTEM
Deposited on 2018-09-06, released 2018-11-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-18, with a file datestamp of 2019-12-13.
Experiment type: XRAY
Resolution: 2.04 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: antibody HEPC3 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MED (0-End)
    Domains in SCOPe 2.08: d6meda_
  • Chain 'B':
    Compound: antibody HEPC3 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MED (0-End)
    Domains in SCOPe 2.08: d6medb1, d6medb2
  • Chain 'C':
    Compound: antibody HEPC3 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MED (0-End)
    Domains in SCOPe 2.08: d6medc_
  • Chain 'D':
    Compound: antibody HEPC3 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MED (0-End)
    Domains in SCOPe 2.08: d6medd1, d6medd2
  • Chain 'G':
    Compound: antibody HEPC3 Heavy Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MED (0-End)
    Domains in SCOPe 2.08: d6medg_
  • Chain 'I':
    Compound: antibody HEPC3 Light Chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6MED (0-End)
    Domains in SCOPe 2.08: d6medi1, d6medi2
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6medA (A:)
qvqlvqsgaevkkpgssvkvsckasggtlnsyeitwvrqapgqglewmggitpifettya
qkfqgrvtitadeststtymelsslrpedtavyycardgvrycgggrcynwfdpwgqgtl
vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6medA (A:)
qvqlvqsgaevkkpgssvkvsckasggtlnsyeitwvrqapgqglewmggitpifettya
qkfqgrvtitadeststtymelsslrpedtavyycardgvrycgggrcynwfdpwgqgtl
vtvssastkgpsvfplapggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssg
lyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvep

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6medB (B:)
diqmtqspsslsasvgdrvtitcragqninnylnwyqqkpgkapkvliyaasnlqsgvps
rfsgsgsgtdftltisslqpedfatyycqqshstvrtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6medB (B:)
diqmtqspsslsasvgdrvtitcragqninnylnwyqqkpgkapkvliyaasnlqsgvps
rfsgsgsgtdftltisslqpedfatyycqqshstvrtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6medC (C:)
qvqlvqsgaevkkpgssvkvsckasggtlnsyeitwvrqapgqglewmggitpifettya
qkfqgrvtitadeststtymelsslrpedtavyycardgvrycgggrcynwfdpwgqgtl
vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6medC (C:)
qvqlvqsgaevkkpgssvkvsckasggtlnsyeitwvrqapgqglewmggitpifettya
qkfqgrvtitadeststtymelsslrpedtavyycardgvrycgggrcynwfdpwgqgtl
vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6medD (D:)
diqmtqspsslsasvgdrvtitcragqninnylnwyqqkpgkapkvliyaasnlqsgvps
rfsgsgsgtdftltisslqpedfatyycqqshstvrtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6medD (D:)
diqmtqspsslsasvgdrvtitcragqninnylnwyqqkpgkapkvliyaasnlqsgvps
rfsgsgsgtdftltisslqpedfatyycqqshstvrtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrg

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6medG (G:)
qvqlvqsgaevkkpgssvkvsckasggtlnsyeitwvrqapgqglewmggitpifettya
qkfqgrvtitadeststtymelsslrpedtavyycardgvrycgggrcynwfdpwgqgtl
vtvssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpa
vlqssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdkthhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6medG (G:)
qvqlvqsgaevkkpgssvkvsckasggtlnsyeitwvrqapgqglewmggitpifettya
qkfqgrvtitadeststtymelsslrpedtavyycardgvrycgggrcynwfdpwgqgtl
vtvssastkgpsvfplapssggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkrvepk

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6medI (I:)
diqmtqspsslsasvgdrvtitcragqninnylnwyqqkpgkapkvliyaasnlqsgvps
rfsgsgsgtdftltisslqpedfatyycqqshstvrtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec

    Sequence, based on observed residues (ATOM records): (download) 
    >6medI (I:)
diqmtqspsslsasvgdrvtitcragqninnylnwyqqkpgkapkvliyaasnlqsgvps
rfsgsgsgtdftltisslqpedfatyycqqshstvrtfgqgtkveikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrge