PDB entry 6mbp

View 6mbp on RCSB PDB site
Description: GLP Methyltransferase with Inhibitor EML741- P3121 Crystal Form
Class: transferase/transferase inhbitor
Keywords: Histone, H3, Methylation Inhibition, TRANSFERASE, TRANSFERASE-TRANSFERASE INHBITOR complex
Deposited on 2018-08-30, released 2019-02-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone-lysine N-methyltransferase EHMT1
    Species: Homo sapiens [TaxId:9606]
    Gene: EHMT1, EUHMTASE1, GLP, KIAA1876, KMT1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6mbpa_
  • Chain 'B':
    Compound: Histone-lysine N-methyltransferase EHMT1
    Species: Homo sapiens [TaxId:9606]
    Gene: EHMT1, EUHMTASE1, GLP, KIAA1876, KMT1D
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6mbpb_
  • Heterogens: JDG, ZN, SAH, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >6mbpA (A:)
verivsrdiargyeripipcvnavdsepcpsnykyvsqncvtspmnidrnithlqycvci
ddcsssncmcgqlsmrcwydkdgrllpefnmaepplifecnhacscwrncrnrvvqnglr
arlqlyrtrdmgwgvrslqdippgtfvceyvgelisdseadvreedsylfdldnkdgevy
cidarfygnvsrfinhhcepnlvpvrvfmahqdlrfpriaffstrlieageqlgfdyger
fwdikgklfscrcgspkcrhs

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6mbpB (B:)
verivsrdiargyeripipcvnavdsepcpsnykyvsqncvtspmnidrnithlqycvci
ddcsssncmcgqlsmrcwydkdgrllpefnmaepplifecnhacscwrncrnrvvqnglr
arlqlyrtrdmgwgvrslqdippgtfvceyvgelisdseadvreedsylfdldnkdgevy
cidarfygnvsrfinhhcepnlvpvrvfmahqdlrfpriaffstrlieageqlgfdyger
fwdikgklfscrcgspkcrhs

    Sequence, based on observed residues (ATOM records): (download) 
    >6mbpB (B:)
erivsrdiargyeripipcvnavdsepcpsnykyvsqncvtspmnidrnithlqycvcid
dcsssncmcgqlsmrcwydkdgrllpefnmaepplifecnhacscwrncrnrvvqnglra
rlqlyrtrdmgwgvrslqdippgtfvceyvgelisdseadvreedsylfdldnkdgevyc
idarfygnvsrfinhhcepnlvpvrvfmahqdlrfpriaffstrlieageqlgfdygerf
wdikgklfscrcgspkcrhs