PDB entry 6m6t

View 6m6t on RCSB PDB site
Description: Amylomaltase from Streptococcus agalactiae in complex with acarbose
Class: transferase
Keywords: amylomaltase, 4-alpha-glucanotransferase, cyclodextrin, acarbose, TRANSFERASE
Deposited on 2020-03-16, released 2021-03-31
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-04-07, with a file datestamp of 2021-04-02.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6m6ta_
  • Chain 'B':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6m6tb1, d6m6tb2
  • Chain 'C':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0E1EIJ0 (2-498)
      • expression tag (1)
      • expression tag (499)
    Domains in SCOPe 2.08: d6m6tc1, d6m6tc2, d6m6tc3
  • Chain 'D':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6m6td_
  • Chain 'E':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed):
    • Uniprot A0A0E1EIJ0 (Start-498)
      • expression tag (499)
    Domains in SCOPe 2.08: d6m6te1, d6m6te2
  • Chain 'F':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6m6tf_
  • Chain 'G':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6m6tg1, d6m6tg2
  • Chain 'H':
    Compound: 4-alpha-glucanotransferase
    Species: STREPTOCOCCUS AGALACTIAE [TaxId:1311]
    Gene: malq
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6m6th_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6m6tA (A:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tA (A:)
    kkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqsf
    savagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknflk
    eeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqkls
    evikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdkq
    plaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgfs
    dyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgfp
    gmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymrr
    lpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlten
    rkaflkeittiynrgn
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6m6tB (B:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tB (B:)
    akkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqs
    fsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknfl
    keeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqkl
    sevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdk
    qplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgf
    sdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgf
    pgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymr
    rlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlte
    nrkaflkeittiynrgn
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6m6tC (C:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tC (C:)
    akkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqs
    fsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknfl
    keeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqkl
    sevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdk
    qplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgf
    sdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgf
    pgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymr
    rlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlte
    nrkaflkeittiynrgnkl
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6m6tD (D:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tD (D:)
    krasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqsfs
    avagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknflke
    eratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqklse
    vikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdkqp
    laiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgfsd
    yweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgfpg
    mkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymrrl
    pnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedltenr
    kaflkeittiynrgnk
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >6m6tE (E:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tE (E:)
    krasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqsfs
    avagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknflke
    eratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqklse
    vikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdkqp
    laiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgfsd
    yweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgfpg
    mkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymrrl
    pnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedltenr
    kaflkeittiynrgnkl
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >6m6tF (F:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tF (F:)
    krasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqsfs
    avagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknflke
    eratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqklse
    vikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdkqp
    laiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgfsd
    yweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgfpg
    mkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymrrl
    pnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedltenr
    kaflkeittiynrgnk
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >6m6tG (G:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tG (G:)
    kkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqsf
    savagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknflk
    eeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqkls
    evikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdkq
    plaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgfs
    dyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgfp
    gmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymrr
    lpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlten
    rkaflkeittiynrgnkl
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >6m6tH (H:)
    makkrasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyq
    sfsavagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknf
    lkeeratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqk
    lsevikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrd
    kqplaiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkg
    fsdyweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtg
    fpgmkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenym
    rrlpnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedlt
    enrkaflkeittiynrgnklehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6m6tH (H:)
    krasgvlmhitslpgdlgigtfgreayafvdflvetdqkfwqilpltttsfgdspyqsfs
    avagnthlidfdlltlegfiskddyqnisfgqdpevvdyaglfekrrpvlekavknflke
    eratrmlsdflqeekwvtdfaefmaikehfgnkalqewddkaiirreeealagyrqklse
    vikyhevtqyffykqwfelkeyandkgiqiigdmpiyvsadsvevwtmpelfkldrdkqp
    laiagvpaddfsddgqlwgnpiynwdyhkesdfdwwiyriqsgvkmydylridhfkgfsd
    yweirgdyqtandgswqpapgpelfatikeklgdlpiiaenlgyideraerllagtgfpg
    mkimefgfydttgnsidiphnytentiayagthdnevingwfenltveqkayaenymrrl
    pnepitetvlrtlyatvsqttitcmqdlldkpadsrmnmpntvggnwqwrmrkedltenr
    kaflkeittiynrgn