PDB entry 6m5y

View 6m5y on RCSB PDB site
Description: Structure of human galectin-1 tandem-repeat mutant with lactose
Class: sugar binding protein
Keywords: Lectin, Beta-Sandwich, Apoptosis, Immune Regulation, SUGAR BINDING PROTEIN
Deposited on 2020-03-12, released 2021-03-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-03-17, with a file datestamp of 2021-03-12.
Experiment type: XRAY
Resolution: 1.38 Å
R-factor: N/A
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Galectin-1,Galectin-1
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P09382 (Start-134)
      • engineered mutation (2)
      • engineered mutation (16)
      • engineered mutation (60)
      • engineered mutation (88)
      • engineered mutation (130)
      • linker (135-137)
    • Uniprot P09382 (138-271)
      • engineered mutation (139)
      • engineered mutation (153)
      • engineered mutation (197)
      • engineered mutation (225)
      • engineered mutation (267)
    Domains in SCOPe 2.08: d6m5ya1, d6m5ya2
  • Heterogens: GAL, BGC, GLC, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6m5yA (A:)
masglvasnlnlkpgeslrvrgevapdaksfvlnlgkdsnnlclhfnprfnahgdantiv
snskdggawgteqreavfpfqpgsvaevsitfdqanltvklpdgyefkfpnrlnleainy
maadgdfkiksvafdgssasglvasnlnlkpgeslrvrgevapdaksfvlnlgkdsnnlc
lhfnprfnahgdantivsnskdggawgteqreavfpfqpgsvaevsitfdqanltvklpd
gyefkfpnrlnleainymaadgdfkiksvafd

    Sequence, based on observed residues (ATOM records): (download) 
    >6m5yA (A:)
sglvasnlnlkpgeslrvrgevapdaksfvlnlgkdsnnlclhfnprfnahgdantivsn
skdggawgteqreavfpfqpgsvaevsitfdqanltvklpdgyefkfpnrlnleainyma
adgdfkiksvafdgssasglvasnlnlkpgeslrvrgevapdaksfvlnlgkdsnnlclh
fnprfnahgdantivsnskdggawgteqreavfpfqpgsvaevsitfdqanltvklpdgy
efkfpnrlnleainymaadgdfkiksvafd