PDB entry 6m4h

View 6m4h on RCSB PDB site
Description: structural mechanism of nucleosome dynamics governed by human histone variants h2a.b and h2a.z.2.2
Deposited on 2020-03-07, released 2020-09-23
The last revision was dated 2021-04-07, with a file datestamp of 2021-04-02.
Experiment type: EM
Resolution: 3.9 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone H3.1
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone H2A-Bbd type 2/3
    Species: Homo sapiens [TaxId:9606]
    Gene: H2AB2, H2AFB2, H2AB3, H2ABBD, H2AFB, H2AFB3
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Histone H2B type 2-E
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST2H2BE, H2BFQ
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Histone H3.1
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: histone h4
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST1H4A, H4/A, H4FA, HIST1H4B, H4/I, H4FI, HIST1H4C, H4/G, H4FG, HIST1H4D, H4/B, H4FB, HIST1H4E, H4/J, H4FJ, HIST1H4F, H4/C, H4FC, HIST1H4H, H4/H, H4FH, HIST1H4I, H4/M, H4FM, HIST1H4J, H4/E, H4FE, HIST1H4K, H4/D, H4FD, HIST1H4L, H4/K, H4FK, HIST2H4A, H4/N, H4F2, H4FN, HIST2H4, HIST2H4B, H4/O, H4FO, HIST4H4
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Histone H2A-Bbd type 2/3
    Species: Homo sapiens [TaxId:9606]
    Gene: H2AB2, H2AFB2, H2AB3, H2ABBD, H2AFB, H2AFB3
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Histone H2B type 2-E
    Species: Homo sapiens [TaxId:9606]
    Gene: HIST2H2BE, H2BFQ
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: DNA (103-mer)
    Species: Homo sapiens [TaxId:9606]
  • Chain 'J':
    Compound: DNA (103-mer)
    Species: Homo sapiens [TaxId:9606]

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6m4hA (A:)
martkqtarkstggkaprkqlatkaarksapatggvkkphryrpgtvalreirryqkste
llirklpfqrlvreiaqdfktdlrfqssavmalqeaceaylvglfedtnlcaihakrvti
mpkdiqlarrirgera

    Sequence, based on observed residues (ATOM records):
    >6m4hA (A:)
llirklpfqrlvreiaqdfktdlrfqssavmalqeaceaylvglfedtnlcaihakrvti
mpkdiqlarrirge

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6m4hB (B:)
msgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlk
vflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records):
    >6m4hB (B:)
niqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtam
dvvyalkrqgrtlygf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6m4hC (C:)
mprrrrrrgssgaggrgrtcsrtvraelsfsvsqverslreghyaqrlsrtapvylaavi
eyltakvlelagneaqnsgernitpllldmvvhndrllstlfntttisqvapged

    Sequence, based on observed residues (ATOM records):
    >6m4hC (C:)
srtvraelsfsvsqverslreghyaqrlsrtapvylaavieyltakvlelagneaqnsge
rnitpllldmvvhndrllstlfntttisqv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6m4hD (D:)
mpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysiyvykvlkqvhpdtgisskam
gimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavt
kytssk

    Sequence, based on observed residues (ATOM records):
    >6m4hD (D:)
sysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiq
tavrlllpgelakhavsegtkavtkyts

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6m4hE (E:)
martkqtarkstggkaprkqlatkaarksapatggvkkphryrpgtvalreirryqkste
llirklpfqrlvreiaqdfktdlrfqssavmalqeaceaylvglfedtnlcaihakrvti
mpkdiqlarrirgera

    Sequence, based on observed residues (ATOM records):
    >6m4hE (E:)
llirklpfqrlvreiaqdfktdlrfqssavmalqeaceaylvglfedtnlcaihakrvti
mpkdiqlarrirge

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6m4hF (F:)
msgrgkggkglgkggakrhrkvlrdniqgitkpairrlarrggvkrisgliyeetrgvlk
vflenvirdavtytehakrktvtamdvvyalkrqgrtlygfgg

    Sequence, based on observed residues (ATOM records):
    >6m4hF (F:)
niqgitkpairrlarrggvkrisgliyeetrgvlkvflenvirdavtytehakrktvtam
dvvyalkrqgrtlygf

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6m4hG (G:)
mprrrrrrgssgaggrgrtcsrtvraelsfsvsqverslreghyaqrlsrtapvylaavi
eyltakvlelagneaqnsgernitpllldmvvhndrllstlfntttisqvapged

    Sequence, based on observed residues (ATOM records):
    >6m4hG (G:)
srtvraelsfsvsqverslreghyaqrlsrtapvylaavieyltakvlelagneaqnsge
rnitpllldmvvhndrllstlfntttisqv

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6m4hH (H:)
mpepaksapapkkgskkavtkaqkkdgkkrkrsrkesysiyvykvlkqvhpdtgisskam
gimnsfvndiferiageasrlahynkrstitsreiqtavrlllpgelakhavsegtkavt
kytssk

    Sequence, based on observed residues (ATOM records):
    >6m4hH (H:)
sysiyvykvlkqvhpdtgisskamgimnsfvndiferiageasrlahynkrstitsreiq
tavrlllpgelakhavsegtkavtkyts

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    No sequence available.