PDB entry 6m1i

View 6m1i on RCSB PDB site
Description: cryoem structure of human pac1 receptor in complex with pacap38
Deposited on 2020-02-26, released 2020-03-11
The last revision was dated 2020-05-27, with a file datestamp of 2020-05-22.
Experiment type: EM
Resolution: 3.5 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pituitary adenylate cyclase-activating polypeptide type I receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6M1I
  • Chain 'B':
    Compound: Pituitary adenylate cyclase-activating polypeptide
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: nanobody 35
    Species: Lama glama [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 6M1I (0-End)
  • Chain 'D':
    Compound: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
    Species: Homo sapiens [TaxId:9606]
    Gene: GNG2
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
    Species: Homo sapiens [TaxId:9606]
    Gene: GNB1
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6M1I (Start-393)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6m1iA (A:)
dykddddkifkkeqamclekiqranelmgfndsspgcpgmwdnitcwkpahvgemvlvsc
pelfrifnpdqdmgvvsrnctedgwsepfphyfdacgfdeyesetgdqdyyylsvkalyt
vgyslslvalllamvilcrfrklhctrnfihmnlfvsfmlraisvfikdwilyaeqdsnh
cfistveckavmvffhycvvsnyfwlfieglylftllvetffperryfywytiigwgapl
vfvtvwatlrlyfddtgcwdmndstalwwvikgpvvgsimvnfvlfigiivilvqklqsp
dmggnessiylrlarstllliplfgihytvfafspenvskrerlvfelglgsfqgfvvav
lycflngevqaeikrkwrswkvnryfavdfkhrhpslasslevlfq

    Sequence, based on observed residues (ATOM records):
    >6m1iA (A:)
ddkifkkeqamclekiqrapgcpgmwdnitcwkpahvgemvlvscpelfrifnpdqdmgv
vsrnctgwsepfphyfdacgfdegdqdyyylsvkalytvgyslslvalllamvilcrfrk
lhctrnfihmnlfvsfmlraisvfikdwilyaeqdsnhcfistveckavmvffhycvvsn
yfwlfieglylftllvetffperryfywytiigwgaplvfvtvwatlrlyfddtgcwdmn
dstalwwvikgpvvgsimvnfvlfigiivilvqklqspdsiylrlarstllliplfgihy
tvfafspenvskrerlvfelglgsfqgfvvavlycflngevqaeikrkwrswk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6m1iB (B:)
hsdgiftdsysryrkqmavkkylaavlgkrykqrvknk

    Sequence, based on observed residues (ATOM records):
    >6m1iB (B:)
hsdgiftdsysryrkqmavkkylaavl

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6m1iC (C:)
qvqlqesggglvqpggslrlscaasgftfsnykmnwvrqapgkglewvsdisqsgasisy
tgsvkgrftisrdnakntlylqmnslkpedtavyycarcpapftrdcfdvtsttyayrgq
gtqvtvsshhhhhh

    Sequence, based on observed residues (ATOM records):
    >6m1iC (C:)
qvqlqesggglvqpggslrlscaasgftfsnykmnwvrqapgkglewvsdisqsgasisy
tgsvkgrftisrdnakntlylqmnslkpedtavyycarcpapftrdcfdvtsttyayrgq
gtqvtv

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6m1iD (D:)
masnntasiaqarklveqlkmeanidrikvskaaadlmayceahakedplltpvpasenp
frekkffcail

    Sequence, based on observed residues (ATOM records):
    >6m1iD (D:)
tasiaqarklveqlkmeanidrikvskaaadlmayceahakedplltpvpasenpfr

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6m1iE (E:)
gmseldqlrqeaeqlknqirdarkacadatlsqitnnidpvgriqmrtrrtlrghlakiy
amhwgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnyvacggldn
icsiynlktregnvrvsrelaghtgylsccrflddnqivtssgdttcalwdietgqqttt
ftghtgdvmslslapdtrlfvsgacdasaklwdvregmcrqtftghesdinaicffpngn
afatgsddatcrlfdlradqelmtyshdniicgitsvsfsksgrlllagyddfncnvwda
lkadragvlaghdnrvsclgvtddgmavatgswdsflkiwn

    Sequence, based on observed residues (ATOM records):
    >6m1iE (E:)
eldqlrqeaeqlknqirdarkacadatlsqitnnidpvgriqmrtrrtlrghlakiyamh
wgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnyvacggldnics
iynlktregnvrvsrelaghtgylsccrflddnqivtssgdttcalwdietgqqtttftg
htgdvmslslapdtrlfvsgacdasaklwdvregmcrqtftghesdinaicffpngnafa
tgsddatcrlfdlradqelmtyshdniicgitsvsfsksgrlllagyddfncnvwdalka
dragvlaghdnrvsclgvtddgmavatgswdsflkiwn

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6m1iF (F:)
mgclgnsktedqrneekaqreankkiekqlqkdkqvyrathrllllgagesgkntivkqm
rilhvngfngeggeedpqaarsnsdgekatkvqdiknnlkeaietivaamsnlvppvela
npenqfrvdyilsvmnvpdfdfppefyehakalwedegvracyersneyqlidcaqyfld
kidvikqadyvpsdqdllrcrvltsgifetkfqvdkvnfhmfdvgaqrderrkwiqcfnd
vtaiifvvasssynmvirednqtnrlqaalklfdsiwnnkwlrdtsvilflnkqdllaek
vlagkskiedyfpefaryttpedatpepgedprvtrakyfirdeflristasgdgrhycy
phftcavdtenirrvfndcrdiiqrmhlrqyell

    Sequence, based on observed residues (ATOM records):
    >6m1iF (F:)
dqrneekaqreankkiekqlqkdkqvyrathrllllgagesgkntivkqsgifetkfqvd
kvnfhmfdvgaqrderrkwiqcfndvtaiifvvanrlqaalklfdsiwnnkwlrdtsvil
flnkqdllaekvlagkskiedyfpefaryttpedatpepgedprvtrakyfirdeflris
tasgdgrhycyphftcavdtenirrvfndcrdiiqrmhlrqyell