PDB entry 6m18

View 6m18 on RCSB PDB site
Description: ace2-b0at1 complex
Deposited on 2020-02-25, released 2020-03-11
The last revision was dated 2020-11-04, with a file datestamp of 2020-10-30.
Experiment type: EM
Resolution: 2.9 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Sodium-dependent neutral amino acid transporter B(0)AT1
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC6A19, B0AT1
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Angiotensin-converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2, UNQ868/PRO1885
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Sodium-dependent neutral amino acid transporter B(0)AT1
    Species: Homo sapiens [TaxId:9606]
    Gene: SLC6A19, B0AT1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Angiotensin-converting enzyme 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACE2, UNQ868/PRO1885
    Database cross-references and differences (RAF-indexed):
  • Heterogens: 3PH, NAG, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6m18A (A:)
madykddddksgpdevdasgrvrlvlpnpgldaripslaeletieqeeassrpkwdnkaq
ymltclgfcvglgnvwrfpylcqshgggafmipflillvlegipllylefaigqrlrrgs
lgvwssihpalkglglasmltsfmvglyyntiiswimwylfnsfqeplpwsdcplnenqt
gyvdecarsspvdyfwyretlnistsisdsgsiqwwmllclacawsvlymctirgiettg
kavyitstlpyvvltiflirgltlkgatngivflftpnvtelaqpdtwldagaqvffsfs
lafgglisfssynsvhnncekdsvivsiingftsvyvaivvysvigfratqryddcfstn
iltlingfdlpegnvtqenfvdmqqrcnasdpaayaqlvfqtcdinaflseavegtglaf
ivfteaitkmplsplwsvlffimlfclglssmfgnmegvvvplqdlrvippkwpkevltg
liclgtfligfiftlnsgqywlslldsyagsiplliiafcemfsvvyvygvdrfnkdief
mighkpnifwqvtwrvvspllmliiflfffvvevsqeltysiwdpgyeefpksqkisypn
wvyvvvvivagvpsltipgyaiyklirnhcqkpgdhqglvstlstasmngdlky

    Sequence, based on observed residues (ATOM records):
    >6m18A (A:)
vlpnpgldaripslaeletieqeeassrpkwdnkaqymltclgfcvglgnvwrfpylcqs
hgggafmipflillvlegipllylefaigqrlrrgslgvwssihpalkglglasmltsfm
vglyyntiiswimwylfnsfqeplpwsdcplnenqtgyvdecarsspvdyfwyretlnis
tsisdsgsiqwwmllclacawsvlymctirgiettgkavyitstlpyvvltiflirgltl
kgatngivflftpnvtelaqpdtwldagaqvffsfslafgglisfssynsvhnncekdsv
ivsiingftsvyvaivvysvigfratqryddcfstniltlingfdlpegnvtqenfvdmq
qrcnasdpaayaqlvfqtcdinaflseavegtglafivfteaitkmplsplwsvlffiml
fclglssmfgnmegvvvplqdlrvippkwpkevltgliclgtfligfiftlnsgqywlsl
ldsyagsiplliiafcemfsvvyvygvdrfnkdiefmighkpnifwqvtwrvvspllmli
iflfffvvevsqeltysiwdpgyeefpksqkisypnwvyvvvvivagvpsltipgyaiyk
lirnh

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6m18B (B:)
mrsssswlllslvavtaawshpqfekqstieeqaktfldkfnheaedlfyqsslaswnyn
tniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngssvlsed
kskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrse
vgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfe
eikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpni
dvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkavchptawdl
gkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimsls
aatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkd
qwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcq
aakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfepl
ftwlkdqnknsfvgwstdwspyadqsikvrislksalgdkayewndnemylfrssvayam
rqyflkvknqmilfgeedvrvanlkprisfnffvtapknvsdiiprtevekairmsrsri
ndafrlndnsleflgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk
nkarsgenpyasidiskgennpgfqntddvqtsf

    Sequence, based on observed residues (ATOM records):
    >6m18B (B:)
tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstl
aqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpq
eclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedy
gdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispi
gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvg
lpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghi
qydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinfl
lkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd
paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlr
lgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyadqsik
vrislksalgdkayewndnemylfrssvayamrqyflkvknqmilfgeedvrvanlkpri
sfnffvtapknvsdiiprtevekairmsrsrindafrlndnsleflgiqptlgppnqppv
siwlivfgvvmgvivvgiviliftgirdr

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6m18C (C:)
madykddddksgpdevdasgrvrlvlpnpgldaripslaeletieqeeassrpkwdnkaq
ymltclgfcvglgnvwrfpylcqshgggafmipflillvlegipllylefaigqrlrrgs
lgvwssihpalkglglasmltsfmvglyyntiiswimwylfnsfqeplpwsdcplnenqt
gyvdecarsspvdyfwyretlnistsisdsgsiqwwmllclacawsvlymctirgiettg
kavyitstlpyvvltiflirgltlkgatngivflftpnvtelaqpdtwldagaqvffsfs
lafgglisfssynsvhnncekdsvivsiingftsvyvaivvysvigfratqryddcfstn
iltlingfdlpegnvtqenfvdmqqrcnasdpaayaqlvfqtcdinaflseavegtglaf
ivfteaitkmplsplwsvlffimlfclglssmfgnmegvvvplqdlrvippkwpkevltg
liclgtfligfiftlnsgqywlslldsyagsiplliiafcemfsvvyvygvdrfnkdief
mighkpnifwqvtwrvvspllmliiflfffvvevsqeltysiwdpgyeefpksqkisypn
wvyvvvvivagvpsltipgyaiyklirnhcqkpgdhqglvstlstasmngdlky

    Sequence, based on observed residues (ATOM records):
    >6m18C (C:)
vlpnpgldaripslaeletieqeeassrpkwdnkaqymltclgfcvglgnvwrfpylcqs
hgggafmipflillvlegipllylefaigqrlrrgslgvwssihpalkglglasmltsfm
vglyyntiiswimwylfnsfqeplpwsdcplnenqtgyvdecarsspvdyfwyretlnis
tsisdsgsiqwwmllclacawsvlymctirgiettgkavyitstlpyvvltiflirgltl
kgatngivflftpnvtelaqpdtwldagaqvffsfslafgglisfssynsvhnncekdsv
ivsiingftsvyvaivvysvigfratqryddcfstniltlingfdlpegnvtqenfvdmq
qrcnasdpaayaqlvfqtcdinaflseavegtglafivfteaitkmplsplwsvlffiml
fclglssmfgnmegvvvplqdlrvippkwpkevltgliclgtfligfiftlnsgqywlsl
ldsyagsiplliiafcemfsvvyvygvdrfnkdiefmighkpnifwqvtwrvvspllmli
iflfffvvevsqeltysiwdpgyeefpksqkisypnwvyvvvvivagvpsltipgyaiyk
lirnh

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6m18D (D:)
mrsssswlllslvavtaawshpqfekqstieeqaktfldkfnheaedlfyqsslaswnyn
tniteenvqnmnnagdkwsaflkeqstlaqmyplqeiqnltvklqlqalqqngssvlsed
kskrlntilntmstiystgkvcnpdnpqeclllepglneimansldynerlwaweswrse
vgkqlrplyeeyvvlknemaranhyedygdywrgdyevngvdgydysrgqliedvehtfe
eikplyehlhayvraklmnaypsyispigclpahllgdmwgrfwtnlysltvpfgqkpni
dvtdamvdqawdaqrifkeaekffvsvglpnmtqgfwensmltdpgnvqkavchptawdl
gkgdfrilmctkvtmddfltahhemghiqydmayaaqpfllrnganegfheavgeimsls
aatpkhlksigllspdfqedneteinfllkqaltivgtlpftymlekwrwmvfkgeipkd
qwmkkwwemkreivgvvepvphdetycdpaslfhvsndysfiryytrtlyqfqfqealcq
aakhegplhkcdisnsteagqklfnmlrlgksepwtlalenvvgaknmnvrpllnyfepl
ftwlkdqnknsfvgwstdwspyadqsikvrislksalgdkayewndnemylfrssvayam
rqyflkvknqmilfgeedvrvanlkprisfnffvtapknvsdiiprtevekairmsrsri
ndafrlndnsleflgiqptlgppnqppvsiwlivfgvvmgvivvgiviliftgirdrkkk
nkarsgenpyasidiskgennpgfqntddvqtsf

    Sequence, based on observed residues (ATOM records):
    >6m18D (D:)
tieeqaktfldkfnheaedlfyqsslaswnyntniteenvqnmnnagdkwsaflkeqstl
aqmyplqeiqnltvklqlqalqqngssvlsedkskrlntilntmstiystgkvcnpdnpq
eclllepglneimansldynerlwaweswrsevgkqlrplyeeyvvlknemaranhyedy
gdywrgdyevngvdgydysrgqliedvehtfeeikplyehlhayvraklmnaypsyispi
gclpahllgdmwgrfwtnlysltvpfgqkpnidvtdamvdqawdaqrifkeaekffvsvg
lpnmtqgfwensmltdpgnvqkavchptawdlgkgdfrilmctkvtmddfltahhemghi
qydmayaaqpfllrnganegfheavgeimslsaatpkhlksigllspdfqedneteinfl
lkqaltivgtlpftymlekwrwmvfkgeipkdqwmkkwwemkreivgvvepvphdetycd
paslfhvsndysfiryytrtlyqfqfqealcqaakhegplhkcdisnsteagqklfnmlr
lgksepwtlalenvvgaknmnvrpllnyfeplftwlkdqnknsfvgwstdwspyadqsik
vrislksalgdkayewndnemylfrssvayamrqyflkvknqmilfgeedvrvanlkpri
sfnffvtapknvsdiiprtevekairmsrsrindafrlndnsleflgiqptlgppnqppv
siwlivfgvvmgvivvgiviliftgirdr